Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 1965112..1965604 Replicon chromosome
Accession NZ_CP048558
Organism Agrobacterium fabrum strain Kin001

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag FY134_RS09730 Protein ID WP_080807612.1
Coordinates 1965335..1965604 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag FY134_RS09725 Protein ID WP_080807616.1
Coordinates 1965112..1965354 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FY134_RS09705 (FY134_09660) 1960362..1961354 + 993 WP_080811835.1 glutathione S-transferase family protein -
FY134_RS09710 (FY134_09665) 1961372..1961863 - 492 WP_010972183.1 NUDIX domain-containing protein -
FY134_RS09715 (FY134_09670) 1961930..1962880 + 951 WP_080807622.1 metallophosphoesterase -
FY134_RS09720 (FY134_09675) 1963085..1964794 - 1710 WP_080807619.1 2-isopropylmalate synthase -
FY134_RS09725 (FY134_09680) 1965112..1965354 - 243 WP_080807616.1 CopG family antitoxin Antitoxin
FY134_RS09730 (FY134_09685) 1965335..1965604 - 270 WP_080807612.1 BrnT family toxin Toxin
FY134_RS09735 (FY134_09690) 1965639..1966817 - 1179 WP_080807609.1 benzoate/H(+) symporter BenE family transporter -
FY134_RS09740 (FY134_09695) 1967080..1968162 + 1083 WP_080807606.1 esterase-like activity of phytase family protein -
FY134_RS09745 (FY134_09700) 1968235..1968879 - 645 WP_111807594.1 NrsF family protein -
FY134_RS09750 (FY134_09705) 1968876..1969391 - 516 WP_262518817.1 sigma-70 family RNA polymerase sigma factor -
FY134_RS09755 (FY134_09710) 1969610..1969867 + 258 WP_111807598.1 pentapeptide MXKDX repeat protein -
FY134_RS09760 (FY134_09715) 1969974..1970555 - 582 WP_006314627.1 ATP-dependent Clp protease proteolytic subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-80)

Antitoxin

CopG antitoxin

(7-71)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10820.24 Da        Isoelectric Point: 8.0187

>T149616 WP_080807612.1 NZ_CP048558:c1965604-1965335 [Agrobacterium fabrum]
MDFEFDPAKSESNKDKHGIDFVEARGLWLDEKRLVVPLETTLEERYIMIAQLRGKCWSAVYTYRHDRVRIISVRRSRDKE
KQRYEDDQR

Download         Length: 270 bp

>T149616 NZ_CP064187:4058347-4058904 [Rhizobium sp. 007]
ATTAAGAAGTCTAGTTACACAGTCATCCTTGATGCTTGCGTCTTGTATCCCGCGCCGCTGCGAGATTTCCTTATGGAACT
CGCTGCGGCGGGACAATTCAGAGCAAAGTGGTCAGATGAGATCCACGATGAATGGACACGAAACGTACTGAAAAACCGTG
ACGACCTTACAATTGAGCAACTCGGTCGCACCAAGGATTTGATGAACGCAGCGGTGCCAGACAGTGTGGTCGATGGCTAT
AGTGATCTTGTGCCTGCGCTTGCGCTTCCGGACCCAGACGATCGGCATGTCCTGGCAGCGGCGATAGTCTCAGCGAGCGA
CGCCATAGTCACGTTTAATCTCTCAGACTTTCCTAGGAAGACCGTTTCACAGTACGATATCGAAGTCCTCCACCCGGACG
ATTTCATCCATCACCAATTTGGCCTGAACAATGCCGGCGTGATAATCGCCGCGCAACATTGTCGAGCTCGTTTGAAAAAC
CCGCCTAAGACGGCATCCGAATATTTAGAAACACTAGAGCGTCAGGGGTTAGCAAAGAGCTGCAACGGGAACTCTTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9110.32 Da        Isoelectric Point: 4.5626

>AT149616 WP_080807616.1 NZ_CP048558:c1965354-1965112 [Agrobacterium fabrum]
MKTISAEEFDRKFDEGEDIDDYLDWSKASRPGLEMVHVDVDLPEKVLRRVDAEAARLGMTRQSLMAKWIAESLEAGRVGK

Download         Length: 243 bp

>AT149616 NZ_CP064187:4057905-4058351 [Rhizobium sp. 007]
ATGTCGCAACTGCTAGAACGCCCAATCCTGCCGTCGGCGGACGATACTGAATTGGCCGCCGAGGCCAGTCGCTACATTTC
ACGTGCGAAGCATGAAGGTGCTGAACTTCGAGTTCAAGTTGATGGCGGGGAGCTCCTAAAGCTTCCCAAGGCTGTCAGCG
AGTTACTGTATCATCTCCTAACTGAAATGGCTCAGGGTAATGCTGTAACTTTGATACCCGTCCATGCTGAGCTGACAACT
CAGGAGGCGGCAGATCATCTTAATGTGTCGCGGCCCTACCTGATCAAACTTTTGGAAGAGGGGAAAATCCCATTCCATAT
GGTTGGAAGCCATCGCCGAATAAAGTTTAGCGACCTGGACGGTTTCCGTCGAAAGGCTGAGGACGAAAGAAAACGGCTCA
TGGACGAGCTGGCGAGCCAGGCCCAAGATTTGGGGATGGGCTATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References