Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapC-relB/VapC(toxin)
Location 12230..12828 Replicon plasmid pAt3
Accession NZ_CP048556
Organism Agrobacterium tumefaciens strain Kin002

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FY136_RS29135 Protein ID WP_023150606.1
Coordinates 12403..12828 (-) Length 142 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FY136_RS29130 Protein ID WP_023150605.1
Coordinates 12230..12406 (-) Length 59 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FY136_RS29115 (FY136_28950) 7456..8541 + 1086 WP_262518609.1 type IV secretion system protein -
FY136_RS29120 (FY136_28955) 10340..11254 - 915 WP_262518610.1 replication protein RepA -
FY136_RS29125 (FY136_28960) 11766..12140 - 375 WP_023150604.1 hypothetical protein -
FY136_RS29130 (FY136_28965) 12230..12406 - 177 WP_023150605.1 hypothetical protein Antitoxin
FY136_RS29135 (FY136_28970) 12403..12828 - 426 WP_023150606.1 type II toxin-antitoxin system VapC family toxin Toxin
FY136_RS29140 (FY136_28975) 12825..13082 - 258 WP_023150607.1 Arc family DNA-binding protein -
FY136_RS29145 (FY136_28980) 13293..13892 + 600 WP_023150609.1 recombinase family protein -
FY136_RS29150 (FY136_28985) 13852..14037 - 186 WP_162751165.1 hypothetical protein -
FY136_RS29155 (FY136_28990) 14050..14748 - 699 WP_023150610.1 hypothetical protein -
FY136_RS29160 (FY136_29000) 15084..15293 - 210 WP_023150612.1 plasmid partition protein ParG -
FY136_RS29165 (FY136_29005) 15306..15935 - 630 WP_262518599.1 ParA family partition ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..16995 16995


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15261.63 Da        Isoelectric Point: 4.6677

>T149611 WP_023150606.1 NZ_CP048556:c12828-12403 [Agrobacterium tumefaciens]
MILLDTNVISEPQRQAPNPRVLDWIDAQALETLYLSSITVAELRAGIALMPAGKRRDGLHENLEKRLLPMFANRVLPFDM
ACTKAYAELLANSRAAGLAVETADAFIAAVALANGFIVATRDTSPFQAAGLEVINPWEASL

Download         Length: 426 bp

>T149611 NZ_CP064180:c2684896-2684793 [Citrobacter amalonaticus]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 59 a.a.        Molecular weight: 6386.06 Da        Isoelectric Point: 4.2096

>AT149611 WP_023150605.1 NZ_CP048556:c12406-12230 [Agrobacterium tumefaciens]
MKQCEQHDAYSRWLAAEIQAAIDDPRPSIPHEEVMAELNATIAGLKERGDPENAAEAP

Download         Length: 177 bp

>AT149611 NZ_CP064180:2684789-2684936 [Citrobacter amalonaticus]
AGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTG
GCATTAATGCAGGCTAAGTCGCCTTGCCTTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTCTGCG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References