Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-DUF971
Location 205124..205709 Replicon chromosome
Accession NZ_CP048552
Organism Agrobacterium tumefaciens strain Kin002

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag FY136_RS15560 Protein ID WP_206913913.1
Coordinates 205124..205426 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag FY136_RS15565 Protein ID WP_206913914.1
Coordinates 205419..205709 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FY136_RS15535 (FY136_15435) 200167..200895 - 729 WP_262517276.1 ABC transporter ATP-binding protein -
FY136_RS15540 (FY136_15440) 200892..201800 - 909 WP_262517277.1 branched-chain amino acid ABC transporter permease -
FY136_RS15545 (FY136_15445) 201797..202669 - 873 WP_262517278.1 branched-chain amino acid ABC transporter permease -
FY136_RS15550 (FY136_15450) 202740..203954 - 1215 WP_262517279.1 amino acid ABC transporter substrate-binding protein -
FY136_RS15555 (FY136_15455) 204089..204961 + 873 WP_262517280.1 helix-turn-helix transcriptional regulator -
FY136_RS15560 (FY136_15460) 205124..205426 + 303 WP_206913913.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FY136_RS15565 (FY136_15465) 205419..205709 + 291 WP_206913914.1 putative addiction module antidote protein Antitoxin
FY136_RS15570 (FY136_15470) 205710..206525 - 816 WP_262517281.1 ABC transporter ATP-binding protein -
FY136_RS15575 (FY136_15475) 206522..207562 - 1041 WP_262517282.1 iron ABC transporter permease -
FY136_RS15580 (FY136_15480) 207559..208602 - 1044 WP_262517283.1 iron ABC transporter permease -
FY136_RS15585 (FY136_15485) 208599..209609 - 1011 WP_262517284.1 iron-siderophore ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(2-95)

Antitoxin

Uncharacterized protein HI1420

(4-95)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11185.74 Da        Isoelectric Point: 9.5496

>T149610 WP_206913913.1 NZ_CP048552:205124-205426 [Agrobacterium tumefaciens]
MQLKQSATFQKWFGKLKDERGKALITSRLNRLFFGHAGDVAPVGNGISELRIHYGPGYRVYFVRSGDVIIVLLCGGDKST
QEKDIKAARQIAAQWSDDDE

Download         Length: 303 bp

>T149610 NZ_CP064180:2307757-2308035 [Citrobacter amalonaticus]
ATGATCATGAATTTCAGGCACAAGGGATTACGCGACCTGTTTCTTCACGGTAAAACGTCAGGCGTGCTGGCAAAGCACGT
CAAACGTTTGCGACACCGCCTCGCCGTGATTGACGCCGCAGGCTGCGTGAACGATATCAACATGCCCGGTTATCGGCTGC
ATCCTCTGAGCGGCGATCGTGATGGCGTCTGGTCAATATCGGTTTCAGGCAACTGGCGTATGACGTTCGAATTCGTCAAT
GGCGATGCGTATATTTTGGATGACGAGGATTATCACTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10427.71 Da        Isoelectric Point: 5.0873

>AT149610 WP_206913914.1 NZ_CP048552:205419-205709 [Agrobacterium tumefaciens]
MSEKFTNFDPAEHLRSDEAIEVFLEDAFATNDAAYIANALGVIARAKGMTQVARETGLAREHLYKSLSETGNPTLETTIA
VLNSLGFQLTSKHKAA

Download         Length: 291 bp

>AT149610 NZ_CP064180:2308035-2308319 [Citrobacter amalonaticus]
ATGAAAATGGCGAATCATCCCCGCCCAGGGGATATCATTCAGGAAGCGCTGGACGAACTGAACGTAAGTTTGCGTGAATT
TGCCAGAGCAATGGAGATTGCGCCCTCAACCGCCAGCCGGTTACTCACGGGCAAAGCGGCACTCACCCCGGAAATGGCGA
TCAAACTCTCGGTGGTGATCGGCAGCTCCCCGGAGATGTGGCTAAATCTGCAAAATACCTGGAGTCTGGCACAAGCGCAA
AAAAGCGTGGACGTGTCCCGTCTGCGCCGTCTGGCGGTGCAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References