Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-dinJ/YafQ-RelB
Location 647387..647994 Replicon chromosome
Accession NZ_CP048551
Organism Agrobacterium tumefaciens strain Kin002

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FY136_RS03270 Protein ID WP_262516746.1
Coordinates 647387..647722 (-) Length 112 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag FY136_RS03275 Protein ID WP_110757494.1
Coordinates 647719..647994 (-) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FY136_RS03255 (FY136_03250) 643440..645632 - 2193 WP_065115178.1 transglycosylase domain-containing protein -
FY136_RS03260 (FY136_03255) 645889..646368 + 480 WP_065115179.1 YcgN family cysteine cluster protein -
FY136_RS03265 (FY136_03260) 646536..647360 + 825 WP_065115180.1 class D beta-lactamase -
FY136_RS03270 (FY136_03265) 647387..647722 - 336 WP_262516746.1 type II toxin-antitoxin system YafQ family toxin Toxin
FY136_RS03275 (FY136_03270) 647719..647994 - 276 WP_110757494.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
FY136_RS03280 (FY136_03275) 648110..648718 + 609 WP_262516747.1 class I SAM-dependent methyltransferase -
FY136_RS03285 (FY136_03280) 648880..651477 + 2598 WP_262516748.1 heavy metal translocating P-type ATPase -
FY136_RS03290 (FY136_03285) 651474..651896 + 423 WP_262516749.1 Cu(I)-responsive transcriptional regulator -
FY136_RS03295 (FY136_03290) 651952..652152 + 201 WP_065115186.1 heavy-metal-associated domain-containing protein -
FY136_RS03300 (FY136_03295) 652229..652498 + 270 WP_065115187.1 type II toxin-antitoxin system ParD family antitoxin -
FY136_RS03305 (FY136_03300) 652488..652853 + 366 WP_262516750.1 type II toxin-antitoxin system RelE/ParE family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(23-110)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-86)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 12836.57 Da        Isoelectric Point: 8.1030

>T149608 WP_262516746.1 NZ_CP048551:c647722-647387 [Agrobacterium tumefaciens]
VTDGKGSEKPAASKRTTLPRSSDFTRQFLKDWQRLNNSGRYDMDKLKKIMLLLVANEGPLPPQFHDHELTGDWRDHRECH
VGGDFLLIYILDEKQNLVVFTRAGTHAELFR

Download         Length: 336 bp

>T149608 NZ_CP064180:c1256536-1256318 [Citrobacter amalonaticus]
ATGTCCGATAAACCATTAACTAAAACTGATTATTTGATGCGCTTGCGACGCTGTCAGACAATTGACACACTTGAACGCGT
GATTGAGAAAAATAAATATGAATTATCTGACAATGAATTGGCTGTATTTTACTCAGCCGCCGATCACCGTCTTGCAGAAT
TGACGATGAATAAACTTTACGACAAGATCCCCTCCTCCGTCTGGAAATTCATTCGTTAA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 9941.54 Da        Isoelectric Point: 8.6850

>AT149608 WP_110757494.1 NZ_CP048551:c647994-647719 [Agrobacterium tumefaciens]
MTANAYVRARIDQAIKDDATAVLDSLGLTVSDVMRMMLTRIAREKALPIELTRPNAETLAAIEEARAIAAARRPRFETAE
AMLTALAGDKR

Download         Length: 276 bp

>AT149608 NZ_CP064180:c1256938-1256564 [Citrobacter amalonaticus]
ATGGATGAATACTCACCCAAAAGACATGATATAGCGCAGCTTAAATTTCTTTGTGAAACGCTTTATCACGACTGTCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTTAACGACCCAACCTCGGCGATCAACCTTCAACTCAACGAACTGATAGAGC
ATATTGCAACCTTCGCACTTAATTATAAAATTAAGTATAATGAGGACAATAAGCTGATTGAGCAGATTGATGAATATCTG
GACGACACATTTATGTTGTTCAGCAGTTATGGCATTAATGCGCAGGATCTGCAGAAATGGCGGAAATCAGGTAATCGCTT
GTTCCGTTGCTTTGTGAATGCCACCAGAGCTAACCCTGTTAGTTTGTCTTGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References