Detailed information of TA system TA149597

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tacT-ataR/DUF1778(antitoxin)
• Location: 1493848..1494666
• Replicon: chromosome
• Accession: NZ_CP048536
• Organism: Agrobacterium tumefaciens strain SJ003

Toxin (Protein)

• Gene name: tacT
• Uniprot ID: -
• Locus tag: FY140_RS06605
• Protein ID: WP_174070414.1
• Coordinates: 1494151..1494666 (+)
• Length: 172 a.a.

Antitoxin (Protein)

• Gene name: ataR
• Uniprot ID: -
• Locus tag: FY140_RS06600
• Protein ID: WP_174070412.1
• Coordinates: 1493848..1494147 (+)
• Length: 100 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FY140_RS06595 (FY140_06560)	1491669..1493324	-	1656	WP_174070788.1	recombinase family protein	-
FY140_RS06600 (FY140_06570)	1493848..1494147	+	300	WP_174070412.1	DUF1778 domain-containing protein	Antitoxin
FY140_RS06605 (FY140_06575)	1494151..1494666	+	516	WP_174070414.1	GNAT family N-acetyltransferase	Toxin
FY140_RS06610 (FY140_06580)	1494673..1496043	-	1371	WP_174070416.1	thiamine biosynthesis protein ThiF	-
FY140_RS06615 (FY140_06585)	1496057..1496578	-	522	WP_174070418.1	hypothetical protein	-
FY140_RS06620 (FY140_06590)	1496526..1496999	-	474	WP_174070420.1	hypothetical protein	-
FY140_RS06625 (FY140_06595)	1496996..1497505	-	510	WP_174070422.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (44-143)

Antitoxin

• Vibrio phage ICP1, Orf50 (12-87)

Sequences

Toxin

Protein

• Length: 172 a.a.
• Molecular weight: 18133.83 Da
• Isoelectric Point: 6.9578

>T149597 WP_174070414.1 NZ_CP048536:1494151-1494666 [Agrobacterium tumefaciens]
VALSAPELLTAAHDVSEFSCGTPTLDHWLKTRALSNQQKGFTVVLVVHEAGRVVGYYGLAPTAVVPAILPRSIRTGQPPD
PVPCLLLGQLATDEAWAGQGIGTGLVKHALQRCVQAANLIGGRALMVNAIDDEAARFWQRRGFMSSKDDPLVLFRSIADI
AASFAEAHAPA

Nucleotide

• Length: 516 bp

>T149597 NZ_CP064174:572192-572725 [Klebsiella pneumoniae]
ATGGAGCAGCAACTGACGATTGAGATGATTGCCGATGCGTTCAGCTACGATATCACTGGATTTGATTGCGGCGAGGAAGC
GCTGAATACGTTTTTAAAAGAGCACCTCAAGCGGCAGCACGATGGACAAATCTTAAGGGGTTATGCGCTGGTCTCCGGGG
ATACCGTTCCCAGGTTGCTGGGTTATTACACCTTATCGGGGAGTTGTTTCGAGCGAGGCATGTTGCCGTCTAAAACTCAG
CAAAAGAAAATCCCGTATCAAAATGCGCCAAGCGTAACCCTCGGGCGGCTGGCCATTGATAAATCTGTTCAGGGGCAGGG
CTGGGGAGAGATGTTGGTTGCCCATGTGATGCGAGTGGTGTGGGGAGCGTCTAAAGCCGTTGGCATCTACGGATTGTTTG
TTGAAGCCCTTAATGAGAAAGCTAAAGCATTCTATCTTCGTCTGGGGTTTATACAGCTCGTGGATGAAAATAGTAACTTA
CTGTTTTATCCGACCAAATCGATTGAACAGCTCTTTACTGACGATGAGTCATAA

Antitoxin

Protein

• Length: 100 a.a.
• Molecular weight: 11120.83 Da
• Isoelectric Point: 4.7174

>AT149597 WP_174070412.1 NZ_CP048536:1493848-1494147 [Agrobacterium tumefaciens]
MATIVERKEYPISMRLPEADVAMIDRAATLRGRSRTDFVRDAAVRAAEDVLMENRLIRMSPEGFAEFMDVLAAPAAPVAE
MVELAQRPAPWETGYEPKR

Nucleotide

• Length: 300 bp

>AT149597 NZ_CP064174:571915-572181 [Klebsiella pneumoniae]
ATGCCCGCACTTAAAAAGCAGCGTATAGATTTGAGATTAACCGATGATGATAAGAGCATCATCGAGGAAGCTGCGGCAAT
TTCGAATCAGACGATTACCCAGTTTGTGGTTGCCAGTGCCTCAGAACGTGCTGCGGAAGTGATTGAGCAGCACCGCAGAA
TGGTCCTCAATGAGCAATCATGGAGCCTGGTGATGGAGGCGATTACCCAACCGCCAGCCCCGAATGATCGACTGAAACGT
GCAGCGAAGCGTCTACAAACCAGGTAA