Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | pasABC/RelE-HTH |
| Location | 330479..330965 | Replicon | chromosome |
| Accession | NZ_CP048518 | ||
| Organism | Agrobacterium tumefaciens strain Sta005 | ||
Toxin (Protein)
| Gene name | pasB | Uniprot ID | A0A846L580 |
| Locus tag | FY144_RS01570 | Protein ID | WP_003503189.1 |
| Coordinates | 330479..330748 (-) | Length | 90 a.a. |
Antitoxin (Protein)
| Gene name | pasA | Uniprot ID | - |
| Locus tag | FY144_RS01575 | Protein ID | WP_121592166.1 |
| Coordinates | 330732..330965 (-) | Length | 78 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FY144_RS01535 (FY144_01540) | 325501..326130 | + | 630 | WP_060722951.1 | DNA-3-methyladenine glycosylase I | - |
| FY144_RS01540 (FY144_01545) | 326127..326573 | + | 447 | WP_060722952.1 | hypothetical protein | - |
| FY144_RS01545 (FY144_01550) | 326589..327632 | - | 1044 | WP_065694890.1 | YeiH family protein | - |
| FY144_RS01550 (FY144_01555) | 327714..328631 | + | 918 | WP_026363679.1 | LysR substrate-binding domain-containing protein | - |
| FY144_RS01555 (FY144_01560) | 328842..329216 | - | 375 | WP_060722954.1 | DUF305 domain-containing protein | - |
| FY144_RS01560 (FY144_01565) | 329274..329666 | - | 393 | WP_003503191.1 | hypothetical protein | - |
| FY144_RS01565 (FY144_01570) | 329708..330472 | - | 765 | WP_003503190.1 | hypothetical protein | - |
| FY144_RS01570 (FY144_01575) | 330479..330748 | - | 270 | WP_003503189.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| FY144_RS01575 (FY144_01580) | 330732..330965 | - | 234 | WP_121592166.1 | DUF6290 family protein | Antitoxin |
| FY144_RS01580 (FY144_01585) | 331123..332646 | + | 1524 | WP_003503187.1 | histidine--tRNA ligase | - |
| FY144_RS01585 (FY144_01590) | 332651..333019 | + | 369 | WP_121592167.1 | VOC family protein | - |
| FY144_RS01590 (FY144_01595) | 333036..334163 | + | 1128 | WP_003503185.1 | ATP phosphoribosyltransferase regulatory subunit | - |
| FY144_RS01595 (FY144_01600) | 334160..334852 | + | 693 | WP_060722955.1 | ATP phosphoribosyltransferase | - |
| FY144_RS01600 (FY144_01605) | 334915..335361 | - | 447 | WP_003503183.1 | DoxX family protein | - |
| FY144_RS01605 (FY144_01610) | 335518..335937 | - | 420 | WP_233282985.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 90 a.a. Molecular weight: 10341.95 Da Isoelectric Point: 10.6086
>T149584 WP_003503189.1 NZ_CP048518:c330748-330479 [Agrobacterium tumefaciens]
MIWKIEFQRAAVKQLGALTKSDANRIVSFLTDRIARDGNPRRTGAALQGSELGNFWRYRVGDYRIICDIQDHKLVVLVVE
IGHRREIYR
MIWKIEFQRAAVKQLGALTKSDANRIVSFLTDRIARDGNPRRTGAALQGSELGNFWRYRVGDYRIICDIQDHKLVVLVVE
IGHRREIYR
Download Length: 270 bp
>T149584 NZ_CP064167:c3793849-3793385 [Escherichia coli O157:H7]
ATGGATTTTCCACAAAGGGTTAATGGTTGGGCGCTATATGCTCATCCCTGTTTTCAGGAAACCTACGACGCTTTAGTTGC
CGAAGTCGAGACATTAAAGGGAAAAGATCCTGAAAATTATCAGAGAAAAGCTGCCACAAAGTTATTGGCGGTGGTCCATA
AAGTGATTGAGGAGCATATCACGGTCAATCCATCATCACCGGCATTCCGTCATGGCAAGTCGTTAGGCTCTGGGAAAAAT
AAAGACTGGTCACGGGTAAAATTTGGTGCTGGTCGCTATCGTCTCTTCTTTCGTTACAGTGAAAAAGAGAAAGTCATCAT
TCTGGGATGGATGAACGATGAAAACACGCTGCGCACCTACGGTAAAAAAACAGATGCCTATACCGTATTCAGCAAAATGT
TAAAAAGAGGACATCCTCCTGCCGACTGGGAAACCCTCACCCGAGAGACAGAAGAAACCCATTGA
ATGGATTTTCCACAAAGGGTTAATGGTTGGGCGCTATATGCTCATCCCTGTTTTCAGGAAACCTACGACGCTTTAGTTGC
CGAAGTCGAGACATTAAAGGGAAAAGATCCTGAAAATTATCAGAGAAAAGCTGCCACAAAGTTATTGGCGGTGGTCCATA
AAGTGATTGAGGAGCATATCACGGTCAATCCATCATCACCGGCATTCCGTCATGGCAAGTCGTTAGGCTCTGGGAAAAAT
AAAGACTGGTCACGGGTAAAATTTGGTGCTGGTCGCTATCGTCTCTTCTTTCGTTACAGTGAAAAAGAGAAAGTCATCAT
TCTGGGATGGATGAACGATGAAAACACGCTGCGCACCTACGGTAAAAAAACAGATGCCTATACCGTATTCAGCAAAATGT
TAAAAAGAGGACATCCTCCTGCCGACTGGGAAACCCTCACCCGAGAGACAGAAGAAACCCATTGA
Antitoxin
Download Length: 78 a.a. Molecular weight: 9198.28 Da Isoelectric Point: 4.6044
>AT149584 WP_121592166.1 NZ_CP048518:c330965-330732 [Agrobacterium tumefaciens]
MSKQTAIRLPDETYERLKALSERTGRTSAYYIREAIEKHIEDMEDLYLAEEATRQRVANKERTYTLEEVMRDLDLEN
MSKQTAIRLPDETYERLKALSERTGRTSAYYIREAIEKHIEDMEDLYLAEEATRQRVANKERTYTLEEVMRDLDLEN
Download Length: 234 bp
>AT149584 NZ_CP064167:c3794184-3793849 [Escherichia coli O157:H7]
ATGCCCGCTAATGCTCGCTCTCACGCTGTACTGACCACTGAATCAAAGGTCACGATACGCGGACAAACAACTATCCCCGC
GCCAGTGCGTGAGGCCTTAAAACTGAAGCCAGGCCAGGACAGCATTCATTACGAAATTCTGCCTGGTGGGCAAGTATTTA
TGTGCCGACTGGGAGATGAGCAGGAGGATCATACTATGAATGCATTTTTGCGTTTTCTGGATACAGATATCCAGAACAAC
CCGCAAAAAACTCGTCCATTCAACATTCAACAAGGAAAGAAACTTGTCGCTGGCATGGACGTCAACATTGATGATGAGAT
TGGCGACGACGAATAA
ATGCCCGCTAATGCTCGCTCTCACGCTGTACTGACCACTGAATCAAAGGTCACGATACGCGGACAAACAACTATCCCCGC
GCCAGTGCGTGAGGCCTTAAAACTGAAGCCAGGCCAGGACAGCATTCATTACGAAATTCTGCCTGGTGGGCAAGTATTTA
TGTGCCGACTGGGAGATGAGCAGGAGGATCATACTATGAATGCATTTTTGCGTTTTCTGGATACAGATATCCAGAACAAC
CCGCAAAAAACTCGTCCATTCAACATTCAACAAGGAAAGAAACTTGTCGCTGGCATGGACGTCAACATTGATGATGAGAT
TGGCGACGACGAATAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|