Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 254750..255420 Replicon plasmid pAt
Accession NZ_CP048471
Organism Agrobacterium tumefaciens strain Yub001

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FY156_RS28730 Protein ID WP_262528616.1
Coordinates 254750..255169 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FY156_RS28735 Protein ID WP_262528617.1
Coordinates 255166..255420 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FY156_RS28710 (FY156_28505) 250442..251188 - 747 WP_262528612.1 SDR family oxidoreductase -
FY156_RS28715 (FY156_28510) 251258..252469 - 1212 WP_262528613.1 ABC transporter substrate-binding protein -
FY156_RS28720 (FY156_28515) 252753..253988 + 1236 WP_262528614.1 CaiB/BaiF CoA-transferase family protein -
FY156_RS28725 (FY156_28520) 254176..254628 - 453 WP_262528615.1 MarR family transcriptional regulator -
FY156_RS28730 (FY156_28525) 254750..255169 - 420 WP_262528616.1 type II toxin-antitoxin system VapC family toxin Toxin
FY156_RS28735 (FY156_28530) 255166..255420 - 255 WP_262528617.1 plasmid stabilization protein Antitoxin
FY156_RS28740 (FY156_28535) 255705..255965 + 261 WP_262528618.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
FY156_RS28745 (FY156_28540) 255955..256362 + 408 Protein_266 hypothetical protein -
FY156_RS28750 (FY156_28545) 256655..257167 + 513 WP_262528619.1 ATP-binding cassette domain-containing protein -
FY156_RS28755 (FY156_28550) 257518..258660 + 1143 WP_262528620.1 Fic family protein -
FY156_RS28760 (FY156_28555) 258671..259690 - 1020 WP_262528621.1 hemagglutinin repeat-containing protein -
FY156_RS28765 (FY156_28560) 259757..260038 + 282 WP_262528622.1 type II toxin-antitoxin system ParD family antitoxin -
FY156_RS28770 (FY156_28565) 260028..260345 + 318 WP_262528623.1 type II toxin-antitoxin system RelE/ParE family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - htpB / htpB 1..401476 401476


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 14996.33 Da        Isoelectric Point: 5.6211

>T149559 WP_262528616.1 NZ_CP048471:c255169-254750 [Agrobacterium tumefaciens]
MILLDTNVISEPWKPAPDPAVLTWLDAQAIETLFISAISIAELRFGIASMPVGKRQAILHDRLESEVLPLFDGRILPFSV
GTSHFYAALMADGRKSGKAIARADGYIAATAAENHLAVVTRDTSPFEAAGLRVINPWVA

Download         Length: 420 bp

>T149559 NZ_CP064129:4166227-4167144 [Klebsiella pneumoniae]
ATGGATATACAGGCGCCTTATTATCGGCAGGTTGCTCTGCTAATGCAGGTTTTACCCTATGTTGCTGTCGAACGGGAATT
TGCGCTGAAAGGTGGCACTGCCATCAATCTCTTTATCCGCGATTTCCCTCGATTATCGGTGGATATCGACCTCGCCTGGG
TGCCCCAGGAAAGCAGAGCCATCGCTTTACCTCATATACGGGATGCGCTTGCACGTATTGCCGCCAATCTGCAACAACAG
GCAGGTATGAGCGCTGTATTACAAGCTAATCGTTCAGATGAGATGCGTGTCATTGTTACTACCGATAGCGCGCAAATAAA
GATAGAGGTTTCACCGGTCGCCCGGGGAACATTATATCCACCACAGGAGCGAGAAGTGGTGGGGGCGGTAGAGGACGTTT
TTGGCTATGCCAGCCTTCCAGTGGTTTCGTTGCCTGACCTCTACGGTGGAAAATTATGCGCGGCGCTGGATCGCCAGCAT
CCCAGAGATTTTTATGACGTGAAATTACTTCTTGATGCGCAGGAGCTTGACCGTCCCATTTTCAATGGGTTTATCGCGTA
TTTACTGAGCCATAATCGGCCTCTGGCTGAAGTGCTGAATCCTCGCTGGAAAGATATTGCTGAACCTTTTTACCGTGAAT
TCAGCGGGATGACATTTGAGACGATAGCCCTGGAGGAACTGACAGCAGTCCCCAACAGGATGATTGCTGCGTTAAAATCC
TGTTTCACACAACAGGATGTCGATTTTTTACTGTCATTTAAACGAGGCGAACCAGACTGGCGTTTAGCGCCGGAAATGCG
TATTCAGGATTTGCCTGCCGTGCAGTGGAAATTGCGCAATATTCATCAGATGCCAGCGATAAAACGCGCTGAGTCATTAG
ATAAACTGGAAAAGGTGCTGGCCGAGTGGCGCAGTTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9212.31 Da        Isoelectric Point: 6.8809

>AT149559 WP_262528617.1 NZ_CP048471:c255420-255166 [Agrobacterium tumefaciens]
MAAVTIRNISDETHRALRARAAHHGRSTEAEIRDILEAAVRPSGRVKLGSLLAAIGRDAELSNSDVEALHQQRDRTPAEP
MTFE

Download         Length: 255 bp

>AT149559 NZ_CP064129:4165463-4166221 [Klebsiella pneumoniae]
ATGGCAACAAAATTAAACTGGCTGCTGCAAAACAGCGCTCCCGGAGATGTGATCCTTCAGTCCTGGTTAAGCCAGCATGC
CATCTCTCCCTCTCTGGCCTTTAAATACGCGCAAAGTGGCTGGTTAAAAAAAAGAGGCAACGGCGTATATGCGCGTGCGG
GACGTGAGCCGGAGTGGAACGATGCATTAGCATGTTTGCAAAATCAGCTTGCCGCTCCGGTGTATGTTGCGGGGCTCAGT
AGCTTAGTCTGGCAGGGCCGTTCACACTATCTACAGCTAAAACAAAACCAGTGCTGGCTTAGTGTGGAAAATAAAGCGCT
GCTGCCGAAATGGTTCAGGGAATTCCCGGGTGTGGAGTGGATAGTCATATCGGGGAAAAAACTGCCGGTGCTGGATGATA
GATACCGTGTAACGCTTGATATAAAAGGGAAAAAACTCATCGGCAGTGCGCCAGAACTGGCTGCTTACGAGTTGCTGAGC
GCGGTGCCGGGGACCCTCTCATTTAACCACGCTGCAGAGCTTTTCCAGGGGCTGGTTAATCTTAATCCTCGTAAAGTAGA
GTATCTTCTTTCCGTCAGCCAGTCCGTGCAGGCCAAGCGTTTGTATCTCTTCTTCGCCAGTTTTTACGAGCATGGCTGGC
TCAAACGAATCGATAGCCAAAAAATCGATCTGGGAGCGGGCAAGCGGCAAATCGTGGAAAATGGAAAGTTCAATGCTCAA
TACCAAATCACAGTGCCTGAACGCTTTCAAAAGGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References