Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 157016..157605 Replicon plasmid pAt
Accession NZ_CP048471
Organism Agrobacterium tumefaciens strain Yub001

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FY156_RS28295 Protein ID WP_262528962.1
Coordinates 157016..157300 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FY156_RS28300 Protein ID WP_262528963.1
Coordinates 157297..157605 (-) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FY156_RS28265 (FY156_28090) 152372..152581 + 210 WP_046802383.1 cold-shock protein -
FY156_RS28270 (FY156_28095) 152712..152936 + 225 WP_262528848.1 hypothetical protein -
FY156_RS28275 (FY156_28100) 153069..153878 + 810 WP_262528960.1 transglutaminase family protein -
FY156_RS28280 (FY156_28105) 153983..154105 - 123 Protein_173 ATP-binding protein -
FY156_RS28285 (FY156_28110) 154336..155439 - 1104 WP_262528961.1 GSU2403 family nucleotidyltransferase fold protein -
FY156_RS28290 (FY156_28115) 156311..156894 + 584 Protein_175 hypothetical protein -
FY156_RS28295 (FY156_28120) 157016..157300 - 285 WP_262528962.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FY156_RS28300 (FY156_28125) 157297..157605 - 309 WP_262528963.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
FY156_RS28305 (FY156_28130) 157936..159828 - 1893 WP_262528965.1 molecular chaperone HtpG -
FY156_RS28310 (FY156_28135) 160259..161173 - 915 WP_262528967.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - htpB / htpB 1..401476 401476


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-53)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10377.84 Da        Isoelectric Point: 5.0190

>T149557 WP_262528962.1 NZ_CP048471:c157300-157016 [Agrobacterium tumefaciens]
VNLAWSAFALSDRDTIFTYIEADNPAAAVLIDERIVSATRRLLDFPASGRVGRIAGTLELVINGTPYIAAYTTTEATVRI
LRVLHGAREWPEYL

Download         Length: 285 bp

>T149557 NZ_CP064129:c3564169-3563684 [Klebsiella pneumoniae]
GTGGGACGTATAACCGCGCCCGAGCCGTTATCCAGCGCTCATCAGCTGGCTGAGTTCGTCAGTGGAGAGACAGTCCTCGA
TGAATGGCTAAAACAGAGAGGTTTAAAAAATCAAGCTCTTGGCGCTGCCCGAACGTTCGTTGTTTGCAAGAAGGGTACGA
AGCAAGTAGCTGGTTTTTACTCTTTGGCCACCGGTAGCGTTAACCATACGGAAGCGACAGGCAGTCTTCGGCGTAACATG
CCAGATCCTATACCGGTGATTATACTCGCTCGCCTGGCGGTAGATGTCTCATTGCGCGGAAAAGGGCTTGGCGCTGATTT
ACTTCATGATGCAGTACTTCGTTGCTATCGGGTTGCCGAGAATATAGGTGTACGTGCAATCATGGTTCATGCGCTCACAG
AAGAAGCCAAAAATTTCTACATTCACCATGGTTTCAAACCATCACAAACTCAGCCGCGGACACTGTTCCTCAGACTCCCT
CAGTAA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11160.61 Da        Isoelectric Point: 5.7471

>AT149557 WP_262528963.1 NZ_CP048471:c157605-157297 [Agrobacterium tumefaciens]
MAANALVQTRIDAKIRDRASEVLESMGLTVSDAVRIMLTRTANEGALPLELLSGSEAHDAWFRTKVLEALNDTRPDLSDD
EVEAHFAKRRAAARLKAGARES

Download         Length: 309 bp

>AT149557 NZ_CP064129:c3564423-3564157 [Klebsiella pneumoniae]
ATGAAATCAGATGTTCAACTCAACCTAAGAGCTAAAGAGTCTCAGAGAGCACTCATCGATGCCGCTGCAGAGATCCTTCA
TAAATCGCGAACCGACTTTATCCTGGAGATGGCCTGCAAGGCTGCGGAGAATGTGATCCTTGATCGCCGTGTTTTCAATT
TTAACGACGAACAGTATGCAGAGTTCATCGATATGCTCGATGCACCAGTCGAGGATGAGCCCGCCATTAATAAACTACTG
GCAAGGAAACCTCAGTGGGACGTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References