Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /-
Location 200885..202404 Replicon chromosome
Accession NZ_CP048469
Organism Agrobacterium tumefaciens strain Yub001

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag FY156_RS00980 Protein ID WP_262524310.1
Coordinates 200885..201400 (+) Length 172 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag FY156_RS00985 Protein ID WP_262524313.1
Coordinates 201526..202404 (+) Length 293 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FY156_RS00940 (FY156_00950) 196042..196434 - 393 WP_262526231.1 hypothetical protein -
FY156_RS00945 (FY156_00955) 196466..196711 - 246 WP_087748648.1 hypothetical protein -
FY156_RS00950 (FY156_00960) 197047..197331 - 285 WP_023102535.1 HigA family addiction module antitoxin -
FY156_RS00955 (FY156_00965) 197341..197619 - 279 WP_075208981.1 type II toxin-antitoxin system RelE/ParE family toxin -
FY156_RS00960 (FY156_00970) 197755..198312 - 558 WP_262524305.1 hypothetical protein -
FY156_RS00965 (FY156_00975) 198637..200205 - 1569 WP_262524306.1 ATP-binding protein -
FY156_RS00970 (FY156_00980) 200296..200445 + 150 WP_262524307.1 hypothetical protein -
FY156_RS00975 (FY156_00985) 200607..200885 + 279 WP_049074335.1 DUF1778 domain-containing protein -
FY156_RS00980 (FY156_00990) 200885..201400 + 516 WP_262524310.1 GNAT family N-acetyltransferase Toxin
FY156_RS00985 (FY156_00995) 201526..202404 + 879 WP_262524313.1 AraC family transcriptional regulator Antitoxin
FY156_RS00990 (FY156_01000) 202699..203430 + 732 WP_262524316.1 AzlC family ABC transporter permease -
FY156_RS00995 (FY156_01005) 203427..203738 + 312 WP_049074350.1 AzlD domain-containing protein -
FY156_RS01000 (FY156_01010) 203850..204920 + 1071 WP_262524319.1 hypothetical protein -
FY156_RS01005 (FY156_01015) 204950..206725 - 1776 WP_262524322.1 DNA cytosine methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(42-144)

Antitoxin

DNA binding HTH domain, AraC-type

(212-289)


Sequences

Toxin        


Download         Length: 172 a.a.        Molecular weight: 18899.71 Da        Isoelectric Point: 7.5182

>T149550 WP_262524310.1 NZ_CP048469:200885-201400 [Agrobacterium tumefaciens]
MALTGPSALAAFHVVDEFDCGKHSLNDWLVRHARQSQSSGSAKTYVVADDQRVVGYFSLTVGQIDTLEAPDRVRKGMGSY
PVPVVILARLAVDQRMHGHEIGVGLLQEAIRRTVIISEQAGVRAMLTHPIDDEAARFYLRFGFEASPVREQQLLLLLKDA
RKLLLPQTGHT

Download         Length: 516 bp

>T149550 NZ_CP064128:3428232-3428528 [Yersinia pestis]
ATGGAGAAACGGACTCCGCATACTCGTTTATTAAAAGTAAAAGAATTGGTATTGAAGGGGAATATTAAAACGACACGAAC
TGCCAGAGATGGGGCTGAGGAACTGGGACTGAGTTTTAGAGATATGTGTGATGCAGTTTCCGAACTGATTAGCGCCGATT
TTTATAAAAGTATGACGACACATCAAGATCATACCATTTGGCAGGATGTTTACCGTCCTATGCTTTCTTGCGGTAGAGTT
TATTTGAAAATCACGGTTATCGATGATGTTTTGAATGTCTCGTTTAAGGAGATTTAA

Antitoxin


Download         Length: 293 a.a.        Molecular weight: 33062.23 Da        Isoelectric Point: 9.6964

>AT149550 WP_262524313.1 NZ_CP048469:201526-202404 [Agrobacterium tumefaciens]
MPGSAILYKKGDRRMAGKKRIEEKARYRHLSELGGLEMLQARYVRQRFPRHVHETYCIGVIEDGAQRFYRSGGEHVAPRG
DIILVNADDVHTGCSELENGWAYRAIYPHPDLFRSISRDIRQPEGSVPWFPDAVLHDPGLAQQLMMTFTLLAQPGNTLFK
ETMLMSSLTWLMMRHGKTRLTPRELPSAEHRVMAIKELIDSCPERDVSLLELAEIAGLSPWHFLRQFKSVVGIPPHAYLV
QARVRKAKELLLKGHPIATVSTLCGFTDQSHLSRHFKGSVGITPGEFVRGFS

Download         Length: 879 bp

>AT149550 NZ_CP064128:3428528-3428926 [Yersinia pestis]
ATGATGAAATGTCCAGTTTGTGGCGGTGTAGAATTAATCCACGAAGCGCGTGACGTTCCCTTTACCTATAAAGGGCGTAA
GTTCATCGTCGAAGGCGTGATAGGGCAACATTGCCCGGCATGCGGTGAAACAGTCATGACCGAAGCCGAGTCCGATGTCT
ATGCAGCAAAAACAATGCTTTTGCGAAAAATGGTCAATACAGAATCGATTGCCCCCGCATATATTGTGCAGATCCGAAAA
AAGTTGGGCCTAAACCAGCGGGAAGCCAGTGAGATTTTTGGTGGTGGGGTTAATGCATTTTCGCGTTACGAAAAAGGTAA
GGCTTTGCCACATCCATCAACGATAAAACTGTTGCAAGTGCTTGATAAACACCCGGAGTTATTGAATGAAATTAGGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References