Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 3067557..3068188 Replicon chromosome
Accession NZ_CP048427
Organism Rhizobium daejeonense strain KACC 13094

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag GT349_RS17775 Protein ID WP_163903795.1
Coordinates 3067790..3068188 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag GT349_RS17770 Protein ID WP_163903793.1
Coordinates 3067557..3067793 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GT349_RS17740 3062618..3063634 - 1017 WP_163903783.1 polyprenyl synthetase family protein -
GT349_RS17745 3063742..3063972 + 231 WP_163903785.1 DUF2007 domain-containing protein -
GT349_RS17750 3064077..3064766 + 690 WP_163906119.1 methyltransferase -
GT349_RS17755 3064787..3066133 - 1347 WP_163903787.1 Nramp family divalent metal transporter -
GT349_RS17760 3066419..3067285 + 867 WP_163903789.1 S49 family peptidase -
GT349_RS17765 3067301..3067492 + 192 WP_163903791.1 hypothetical protein -
GT349_RS17770 3067557..3067793 + 237 WP_163903793.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
GT349_RS17775 3067790..3068188 + 399 WP_163903795.1 PIN domain-containing protein Toxin
GT349_RS17780 3068289..3069248 + 960 WP_163903797.1 glycine--tRNA ligase subunit alpha -
GT349_RS17785 3069372..3071192 + 1821 WP_163903799.1 DUF2207 domain-containing protein -
GT349_RS17790 3071322..3071873 + 552 WP_163903800.1 LemA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-114)

Antitoxin

SpoVT-AbrB domain

(5-36)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14477.74 Da        Isoelectric Point: 4.2790

>T149416 WP_163903795.1 NZ_CP048427:3067790-3068188 [Rhizobium daejeonense]
MNPPLLDTNILIYAFSDDQKAGRAQECLAQPFVLSTQALNEFANVALRKLGMTAPEVRIAIADICLLAEDIFPLDRRTHE
MALDIAERYRLSFYDSLMLSAACLAGCPSCLSEDMQHGLLIEGGTTVANPFI

Download         Length: 399 bp

>T149416 NZ_CP064095:c1440439-1440089 [Bacillus subtilis]
TTGATTGTGAAACGCGGCGATGTTTATTTTGCTGATTTATCTCCTGTTGTTGGCTCAGAGCAAGGCGGGGTGCGCCCGGT
TTTAGTGATCCAAAATGACATCGGAAATCGCTTCAGCCCAACTGCTATTGTTGCAGCCATAACAGCACAAATACAGAAAG
CGAAATTACCAACCCACGTCGAAATCGATGCAAAACGCTACGGTTTTGAAAGAGATTCCGTTATTTTGCTGGAGCAAATT
CGGACGATTGACAAGCAAAGGTTAACGGATAAGATTACTCATCTGGATGATGAAATGATGGATAAGGTTGATGAAGCCTT
ACAAATCAGTTTGGCACTCATTGATTTTTAG

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8810.83 Da        Isoelectric Point: 6.3503

>AT149416 WP_163903793.1 NZ_CP048427:3067557-3067793 [Rhizobium daejeonense]
MQVSRWGNSLAIRIPVAVAEALELKEGDEVNVRVSGSRTFEIGREDSREQALTRIRNARISLPAGWTFDRDEANERRG

Download         Length: 237 bp

>AT149416 NZ_CP064095:c1440725-1440444 [Bacillus subtilis]
TTGTCTGAATCCAGCGCAAGAACCGAAATGAAAATCAGCTTGCCCGAAAACCTAGTAGCTGAATTGGATGGTGTAGCGAT
GCGGGAGAAACGAAGCAGAAACGAACTGATATCACAAGCAGTGAGAGCGTATGTCAGCGAACGAACAACTCGTCACAACC
GTGATTTGATGAGACGCGGCTATATGGAAATGGCGAAAATCAACCTGAATATTTCTTCTGAGGCTCACTTTGCGGAGTGC
GAGGCTGAAACGACAGTTGAGCGCTTAGTCAGCGGAGGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References