Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 28319..29118 Replicon plasmid unnamed1
Accession NZ_CP048424
Organism Rhizobium daejeonense strain KACC 13094

Toxin (Protein)


Gene name TacT3 Uniprot ID -
Locus tag GT349_RS00170 Protein ID WP_163897145.1
Coordinates 28594..29118 (+) Length 175 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID -
Locus tag GT349_RS00165 Protein ID WP_163897143.1
Coordinates 28319..28597 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GT349_RS00130 23891..24525 - 635 Protein_25 IS3 family transposase -
GT349_RS00135 24518..25333 - 816 Protein_26 extracellular solute-binding protein -
GT349_RS00140 25321..25455 + 135 Protein_27 IS3 family transposase -
GT349_RS00145 25559..26269 - 711 WP_163897135.1 autoinducer binding domain-containing protein -
GT349_RS00150 26502..27275 - 774 WP_163897137.1 winged helix-turn-helix domain-containing protein -
GT349_RS00155 27426..27632 + 207 WP_163897139.1 hypothetical protein -
GT349_RS00160 27803..28123 + 321 WP_163897141.1 hypothetical protein -
GT349_RS00165 28319..28597 + 279 WP_163897143.1 DUF1778 domain-containing protein Antitoxin
GT349_RS00170 28594..29118 + 525 WP_163897145.1 GNAT family N-acetyltransferase Toxin
GT349_RS00175 29785..30501 + 717 WP_163897147.1 response regulator transcription factor -
GT349_RS00180 30498..31859 + 1362 WP_163897149.1 amidohydrolase family protein -
GT349_RS00185 31929..33377 - 1449 WP_163897152.1 MmgE/PrpD family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..256449 256449
- flank IS/Tn - - 24193..24369 176


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(35-145)

Antitoxin

Vibrio phage ICP1, Orf50

(13-87)


Sequences

Toxin        


Download         Length: 175 a.a.        Molecular weight: 18807.59 Da        Isoelectric Point: 9.1674

>T149414 WP_163897145.1 NZ_CP048424:28594-29118 [Rhizobium daejeonense]
MTAWHEEAIGKHHDRKNFDCGDPELNHFLQKYAPQSHDHGGSKTFLAVRDDASKQILGFCSLTPPSIDPGKVPVAVRKGL
GQHEVPGFRLTRLGVDRPQQGKGMGGQLMLAAGKRCLRAASEVGGVVLAIDAKNDRVAEWYRTYGAIRLVDSPLSLVIPL
ATIPEALKAAGHTL

Download         Length: 525 bp

>T149414 NZ_CP064094:c3616227-3616135 [Bacillus subtilis]
ATGTCAACATTCCAGGCATTAATGCTAATGCTTGCAATCGGGTCGTTTATAATCGCCCTATTGACGTATATAGAAAAAAT
AGACCTCCCTTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10059.56 Da        Isoelectric Point: 6.3300

>AT149414 WP_163897143.1 NZ_CP048424:28319-28597 [Rhizobium daejeonense]
MPSIANENNELVSLRIPAAAKAKLVRAAALRNIDLTNFVTQSALREADAVIEQAESIKVSERDFLRILDLLENPPAPNEQ
LRAAARSLPKSI

Download         Length: 279 bp

>AT149414 NZ_CP064094:3615981-3616154 [Bacillus subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References