Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(antitoxin)
Location 4422316..4422875 Replicon chromosome
Accession NZ_CP048409
Organism Draconibacterium sp. M1

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag G0Q07_RS17985 Protein ID WP_163348456.1
Coordinates 4422630..4422875 (-) Length 82 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag G0Q07_RS17980 Protein ID WP_163348455.1
Coordinates 4422316..4422639 (-) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G0Q07_RS17965 4418239..4418874 + 636 WP_163348452.1 DNA-3-methyladenine glycosylase 2 family protein -
G0Q07_RS17970 4418923..4419426 + 504 WP_163348453.1 hypothetical protein -
G0Q07_RS17975 4419514..4422114 + 2601 WP_163348454.1 TonB-dependent receptor -
G0Q07_RS17980 4422316..4422639 - 324 WP_163348455.1 type II toxin-antitoxin system PemK/MazF family toxin Antitoxin
G0Q07_RS17985 4422630..4422875 - 246 WP_163348456.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Toxin
G0Q07_RS17990 4423171..4423419 - 249 WP_163348457.1 hypothetical protein -
G0Q07_RS17995 4423618..4424916 - 1299 WP_163348458.1 hypothetical protein -
G0Q07_RS18000 4425827..4426567 + 741 WP_163348459.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

mRNA interferase PemK-like

(2-102)


Sequences

Toxin        


Download         Length: 82 a.a.        Molecular weight: 9351.84 Da        Isoelectric Point: 5.1708

>T149387 WP_163348456.1 NZ_CP048409:c4422875-4422630 [Draconibacterium sp. M1]
MEISVIKIGNSKGIRLSKTLLDRYNIKDTVDLIMDKGQIIIKPISKPRKGWEKAFEKMAKSGDDNLLIDDVFDDENLEEW
K

Download         Length: 246 bp

>T149387 NZ_CP064056:898102-898458 [Staphylococcus lloydii]
ATGAGAAGAGGAGATGTATATCTAGCTGATTTATCACCAGTACAAGGGTCTGAACAAGGGGGAGTAAGACCGGTAGTTAT
CATACAAAATGATACTGGTAATAAATATAGTCCTACCGTAATTGTGGCTGCAATTACTGGTAGGATTAATAAAGCTAAAA
TCCCAACGCACGTAGAAATAGAAAAGAAAAAGTATAAGCTGGATAAAGATTCGGTTATACTACTTGAACAAATAAGAACG
TTAGATAAAAAGAGACTAAAAGAAAAATTAACGTATTTATCAGAAGACAAGATGAAAGAAGTCAATAATGCGCTTGATAT
TAGTTTAGGATTACATAATGTTAGAAATCACAAATAA

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 12564.88 Da        Isoelectric Point: 10.0755

>AT149387 WP_163348455.1 NZ_CP048409:c4422639-4422316 [Draconibacterium sp. M1]
MEIKQYQIILVNLDPTIGSEIKKTRPCVVISPNEMNKYLRTVVIAPMTTSSKKYPTRVKVKHDKKMGWIVLDQIRTIDRQ
RIIKVFGELQDFEIQELKSVLKETYID

Download         Length: 324 bp

>AT149387 NZ_CP064056:897932-898102 [Staphylococcus lloydii]
ATGTCAAGTTTTAACCAAAGTAGAAACCATAATATAGAACAATCTTTAAAAGAAGGCTATTCTCAAATGGCTGATTTGAA
TCTCTCCCTTGCAGCAGAAGCTTTTCCCTTTGAATGTGAAGCTTGTGATTGCAATGAATCTTATATTAGTTCAAATAACA
CAAGTGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References