Detailed information of TA system TA149383

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 2575051..2575531
• Replicon: chromosome
• Accession: NZ_CP048408
• Organism: Pseudomonas fluorescens strain DR397

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: GZH78_RS11555
• Protein ID: WP_080770598.1
• Coordinates: 2575051..2575335 (-)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: GZH78_RS11560
• Protein ID: WP_103387228.1
• Coordinates: 2575325..2575531 (-)
• Length: 69 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GZH78_RS11515	2570263..2570736	+	474	WP_011333434.1	type II secretion system GspH family protein	-
GZH78_RS11520	2570742..2571116	+	375	WP_011333435.1	type II secretion system GspH family protein	-
GZH78_RS11525	2571091..2571642	+	552	WP_163974570.1	type II secretion system GspH family protein	-
GZH78_RS11530	2571639..2572031	+	393	WP_064378911.1	curli production assembly/transport protein CsgE	-
GZH78_RS11535	2572028..2572459	+	432	WP_007956141.1	curli production assembly protein CsgF	-
GZH78_RS11540	2572489..2573349	+	861	WP_064378912.1	curli production assembly/transport protein CsgG	-
GZH78_RS11545	2574267..2574647	+	381	WP_163974572.1	hypothetical protein	-
GZH78_RS11550	2574719..2574910	+	192	WP_163974574.1	antitoxin	-
GZH78_RS11555	2575051..2575335	-	285	WP_080770598.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
GZH78_RS11560	2575325..2575531	-	207	WP_103387228.1	antitoxin	Antitoxin
GZH78_RS11565	2575801..2577252	-	1452	WP_103387229.1	curlin	-
GZH78_RS11570	2577279..2577743	-	465	WP_007956150.1	curlin	-
GZH78_RS11575	2577813..2580047	-	2235	WP_163974575.1	cadherin-like domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-88)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 10918.75 Da
• Isoelectric Point: 10.9931

>T149383 WP_080770598.1 NZ_CP048408:c2575335-2575051 [Pseudomonas fluorescens]
MQIKWRPKARVELSKILKYIGERNFVAATALHKSVVKTTSALPWHPHLYRKGRSPGTREIVVSPNYLVVYQVADRIEIVS
ILHARQEYPRRDPS

Nucleotide

• Length: 285 bp

>T149383 NZ_CP064054:c3928339-3927833 [Morganella morganii subsp. morganii]
TTGAACTTAACGGCACCGGAACCCTTGCAGCAGCATCATGATTTTACCGTTTTTCAGTCAGGTGAGGAGTCCCTTAACCA
TTGGCTGAAAACCCGCGCATTGCAAAATCAGCAATCCGGAGCCTCACGGACATTTGTCGTCTGCCACCATAACCGGATAA
TGGCCTATTATGCATTATCGACAGGCGTTATTACCTGTTCACAGGCGGCGGGTCGTTTCAGACGTAATATGCCCCCGGAA
ATTCCGGTTATCCTGCCGGGACGTCTTGCTGTTGACGAAAGCGTAAAAGGCAGAGGGATCGGACGGGGTCTGATAAAAGA
TGCCGCACTGCGGGTCTTGCAGGCGGCCGGGATTGTGGGTATCCGCGGTATTGTTGTCCGTGCTCTGTCTGATAATGCCA
GACGTTTTTATGAGCATACCGGTTTTATGCCGTCACCGGCTGACCCGATGCTGCTGATGATTACATTACGGGATCTGCAG
CTGGCAACCGGCATCTATTCTGAATAG

Antitoxin

Protein

• Length: 69 a.a.
• Molecular weight: 7556.46 Da
• Isoelectric Point: 3.9012

>AT149383 WP_103387228.1 NZ_CP048408:c2575531-2575325 [Pseudomonas fluorescens]
MIDPSLIDPLCPVVSDLGPEEQAASYDRWFRAEVQASLDDPRPSIPHEQVMAEINALMESMRKSADAD

Nucleotide

• Length: 207 bp

>AT149383 NZ_CP064054:c3928650-3928342 [Morganella morganii subsp. morganii]
ATGACAAAACACACAGATGAGCAGCATCCTGTGTCCGGCGTGAATATCACCCGTTCAACACTGAATTTACGCATCAAACC
GGAAGATAAAATTCTGATTGATCGCGCAGCGCATGCTGCCGGTAAAAACAGAACCGAGTTCGTACTGGAAGCTGCGCGGC
GTGCCGCCGAAGAAACACTGGCAGATTTACGGGTTATTGATGTCAGTACCGATGTCTATCAGCAGTTTATTACCAGACTG
GATATGGCACCACAGTCCGGTGAGGCGCTGAAGAAGACCATGCTGACGAAGGCGCCGTGGGAGAAGTAA