Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-RelB
Location 230591..231132 Replicon chromosome
Accession NZ_CP048405
Organism Streptacidiphilus sp. PB12-B1b

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GXW83_RS01050 Protein ID WP_182440994.1
Coordinates 230591..230857 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GXW83_RS01055 Protein ID WP_182440995.1
Coordinates 230854..231132 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GXW83_RS01035 227209..228516 + 1308 WP_182440992.1 MoxR family ATPase -
GXW83_RS01040 228660..229865 + 1206 WP_182440993.1 hypothetical protein -
GXW83_RS01045 230003..230428 - 426 WP_182447735.1 hypothetical protein -
GXW83_RS01050 230591..230857 - 267 WP_182440994.1 Txe/YoeB family addiction module toxin Toxin
GXW83_RS01055 230854..231132 - 279 WP_182440995.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
GXW83_RS01060 231166..231687 - 522 WP_182446956.1 SMI1/KNR4 family protein -
GXW83_RS01065 232124..232969 + 846 WP_182440996.1 hypothetical protein -
GXW83_RS01070 233033..233272 - 240 WP_182447736.1 hypothetical protein -
GXW83_RS01075 233449..233790 + 342 WP_182440997.1 hypothetical protein -
GXW83_RS01080 233794..234507 - 714 WP_182440998.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10542.99 Da        Isoelectric Point: 7.9008

>T149374 WP_182440994.1 NZ_CP048405:c230857-230591 [Streptacidiphilus sp. PB12-B1b]
MKIQFTDGGWTDYLYWQANDRRLLKRINQLIDDIRRNGHEGIGKPEPLRHELAGAWSRRIDQEHRLVYVLDEQADMVCVI
ACRYHYSK

Download         Length: 267 bp

>T149374 NZ_CP064048:1510771-1511121 [Anoxybacillus sediminis]
GTGATTGTCAAACGTGGCGATGTGTTTTTCGCTGACCTGTCACCGGTCGTTGGCTCTGAACAGGGAGGCGTACGGCCTGT
TTTAGTGATTCAAAACGATATTGGCAATCGCTTTAGTCCAACGGTCATCGTCGCCGCCATTACGGCGCAGATTCAGAAGG
CTAAACTGCCGACGCATGTAGAGATTGACGCAAAAACGTACGGATTTGACCGTGACTCCGTAATTCTGCTGGAACAGATT
CGAACCATTGACAAACAACGGCTGACCGATAAGATAACGCATCTGGACGACGAGATGATGGATCGCGTCAATGAATCCCT
GCAGATCAGCCTGGGACTCATTGACTTTTAA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10288.29 Da        Isoelectric Point: 4.2392

>AT149374 WP_182440995.1 NZ_CP048405:c231132-230854 [Streptacidiphilus sp. PB12-B1b]
MKTMSATELRSNLAAALDSVENDAEELVITRAGHEPLVVVSLAEYASLRETDYLLRSPANADHLRQSLRDYQEGRTQNRE
LIDPEDATEQST

Download         Length: 279 bp

>AT149374 NZ_CP064048:1510468-1510767 [Anoxybacillus sediminis]
ATGGTTGGAGGTGGATTTGTCTTGTCTAAGTCTAACACGAAACGCATCATGATCAGCTTGCCACATCACCTGCTTCAGGA
AGTGGATGGCGTTATTCAGAAAGAAAAATCCAATCGCAGCGAGTTTATTCGCCAGGCGATGCACCTTTACTTGAAAGAGC
GCAAAAAGCGTGTCATTCGCGAAACCATGCAAAAAGGTTACATGGAAATGGCGAAAATCAATCTGAAAATGGCATCGGAG
GCATTTGGCGCAGAGGAAGAGGCTGACCATACTCTTATCCGCTTAGTTAGCGGGGTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References