Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1977902..1978047 Replicon chromosome
Accession NZ_CP048389
Organism Klebsiella pneumoniae strain S01

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1977938..1978040 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1977902..1978047 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GZH33_RS09510 1973032..1975092 + 2061 WP_004151449.1 oligopeptidase B -
GZH33_RS09515 1975096..1975755 - 660 WP_002911407.1 exodeoxyribonuclease X -
GZH33_RS09520 1975834..1976064 - 231 WP_002911406.1 DNA polymerase III subunit theta -
GZH33_RS09525 1976177..1976551 + 375 WP_004151448.1 CopC domain-containing protein YobA -
GZH33_RS09530 1976555..1977424 + 870 WP_009307538.1 copper homeostasis membrane protein CopD -
GZH33_RS09535 1977441..1977779 + 339 WP_009307539.1 YebY family protein -
- 1977902..1978047 - 146 - - Antitoxin
- 1977938..1978040 + 103 - - Toxin
GZH33_RS09540 1978416..1978559 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
GZH33_RS09545 1978664..1979632 - 969 WP_004151446.1 VirK/YbjX family protein -
GZH33_RS09550 1979789..1980442 + 654 WP_009307541.1 protein-serine/threonine phosphatase -
GZH33_RS09555 1980439..1980630 - 192 WP_002911395.1 YebW family protein -
GZH33_RS09560 1980728..1980967 - 240 WP_002911393.1 YebV family protein -
GZH33_RS09565 1981083..1982516 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T149350 NZ_CP048389:1977938-1978040 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT149350 NZ_CP048389:c1978047-1977902 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References