Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4402208..4402743 Replicon chromosome
Accession NZ_CP048388
Organism Citrobacter portucalensis strain PNUCL1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GZH81_RS20700 Protein ID WP_048227467.1
Coordinates 4402456..4402743 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID D4BKM9
Locus tag GZH81_RS20695 Protein ID WP_006688247.1
Coordinates 4402208..4402459 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GZH81_RS20665 (4397685) 4397685..4398443 + 759 WP_003844769.1 phosphonate C-P lyase system protein PhnK -
GZH81_RS20670 (4398565) 4398565..4399251 + 687 WP_003826708.1 phosphonate C-P lyase system protein PhnL -
GZH81_RS20675 (4399248) 4399248..4400384 + 1137 WP_103015272.1 alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase -
GZH81_RS20680 (4400387) 4400387..4400941 + 555 WP_008786953.1 ribose 1,5-bisphosphokinase -
GZH81_RS20685 (4400928) 4400928..4401362 + 435 WP_048215113.1 aminoalkylphosphonate N-acetyltransferase -
GZH81_RS20690 (4401371) 4401371..4402129 + 759 WP_103015271.1 phosphonate metabolism protein PhnP -
GZH81_RS20695 (4402208) 4402208..4402459 + 252 WP_006688247.1 plasmid stabilization protein Antitoxin
GZH81_RS20700 (4402456) 4402456..4402743 + 288 WP_048227467.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GZH81_RS20705 (4402740) 4402740..4403069 - 330 WP_003031807.1 DDRRRQL repeat protein YjdP -
GZH81_RS20710 (4403139) 4403139..4405403 - 2265 WP_212024479.1 hybrid sensor histidine kinase/response regulator -
GZH81_RS20715 (4405518) 4405518..4407041 + 1524 WP_212024481.1 sugar ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11165.14 Da        Isoelectric Point: 10.3527

>T149343 WP_048227467.1 NZ_CP048388:4402456-4402743 [Citrobacter portucalensis]
MSYTVKFREDALKEWQKLDKAIQQQFAKKLKKCCENPHIPSAKLRGIKDCYKIKLRTSGFRLVYQVIDDTLVIVVVAVGK
RERSEVYNLASERFR

Download         Length: 288 bp

>T149343 NZ_CP064005:908441-908575 [Xanthomonas translucens pv. translucens]
ATGAAGCGTACTTTCGCGTGGATGCTGCTGGCGATGTTCTCGGTGGGCCTGCTGTCGGGCTGCAACACGGTTGCCGGTGC
CGGCAAGGACGTGAAGAGCGCCGGCGAGAAGGTCGAAGACGCCGCCAAGAACTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9215.53 Da        Isoelectric Point: 4.2965

>AT149343 WP_006688247.1 NZ_CP048388:4402208-4402459 [Citrobacter portucalensis]
MPHIILSDTTASVSELKKNPMATVSAGDGFPVAILNRNQPAFYCVPAELYEKMLDALDDQQLVKLVHERSQQPLVDVDLD
SYL

Download         Length: 252 bp

>AT149343 NZ_CP064005:908190-908342 [Xanthomonas translucens pv. translucens]
ATGAAGCGACTGTTCACCTTGACGATGCTGACCCTGTTTTGTGCAGGCATGCTGACCGGCTGCAACACCATGGCCGGCGC
CGGTAAGGACATGCAGAAGGCCGGCGATAAGGTGGAAACCAAGGCCGACGACTGTAAAGACGGCAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7X1BT32

References