Detailed information of TA system TA149327

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): yfjZ-ypjF/CbtA-CbeA
• Location: 1151954..1152612
• Replicon: chromosome
• Accession: NZ_CP048388
• Organism: Citrobacter portucalensis strain PNUCL1

Toxin (Protein)

• Gene name: ypjF
• Uniprot ID: -
• Locus tag: GZH81_RS05370
• Protein ID: WP_212025038.1
• Coordinates: 1151954..1152274 (-)
• Length: 107 a.a.

Antitoxin (Protein)

• Gene name: yfjZ
• Uniprot ID: -
• Locus tag: GZH81_RS05375
• Protein ID: WP_212025040.1
• Coordinates: 1152295..1152612 (-)
• Length: 106 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GZH81_RS05365 (1147840)	1147840..1151382	-	3543	WP_212025035.1	inverse autotransporter beta domain-containing protein	-
GZH81_RS05370 (1151954)	1151954..1152274	-	321	WP_212025038.1	TA system toxin CbtA family protein	Toxin
GZH81_RS05375 (1152295)	1152295..1152612	-	318	WP_212025040.1	type IV toxin-antitoxin system YeeU family antitoxin	Antitoxin
GZH81_RS05380 (1152631)	1152631..1152852	-	222	WP_212025042.1	DUF987 domain-containing protein	-
GZH81_RS05385 (1152861)	1152861..1153337	-	477	WP_212025044.1	RadC family protein	-
GZH81_RS05390 (1153353)	1153353..1153832	-	480	WP_212025046.1	antirestriction protein	-
GZH81_RS05395 (1154592)	1154592..1155467	-	876	WP_212025048.1	plasmid partitioning protein RepB C-terminal domain-containing protein	-
GZH81_RS05400 (1155470)	1155470..1156354	-	885	WP_212025050.1	ParB/RepB/Spo0J family partition protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• CbtA toxin of type IV toxin-antitoxin system (1-104)

Antitoxin

• Antitoxin CbeA (5-104)

Sequences

Toxin

Protein

• Length: 107 a.a.
• Molecular weight: 11999.89 Da
• Isoelectric Point: 7.1656

>T149327 WP_212025038.1 NZ_CP048388:c1152274-1151954 [Citrobacter portucalensis]
MKTLPATTPQAAKPCLSPVAVWQMLLSRLLDQHYGLTLNDTPFSDETAIKEHIDAGISLADAVNFLVEKYELVRIDRKGF
SWQEQSPFITAVDILKARRAIREMRT

Nucleotide

• Length: 321 bp

>T149327 NZ_CP064002:786540-786674 [Xanthomonas translucens pv. translucens]
ATGAAGCGTACTTTCGCGTGGATGCTGCTGGCGATGTTCTCGGTGGGCCTGCTGTCGGGCTGCAACACGGTTGCCGGTGC
CGGCAAGGACGTGAAGAGCGCCGGCGAGAAGGTCGAAGACGCCGCCAAGAACTGA

Antitoxin

Protein

• Length: 106 a.a.
• Molecular weight: 11788.38 Da
• Isoelectric Point: 6.2009

>AT149327 WP_212025040.1 NZ_CP048388:c1152612-1152295 [Citrobacter portucalensis]
MSNITWGLQLDITPHLGARLIQEGNRLHYLADRASITGKFSDAECLKLDEAFPHFISQIESMLTTGEMNPRHAHCVTLYH
NGFTCEADTLGSCGYIYIAVYPTQR

Nucleotide

• Length: 318 bp

>AT149327 NZ_CP064002:786289-786441 [Xanthomonas translucens pv. translucens]
ATGAAGCGACTGTTCACCTTGACGATGCTGACCCTGTTTTGTGCAGGCATGCTGACCGGCTGCAACACCATGGCCGGCGC
CGGTAAGGACATGCAGAAGGCCGGCGATAAGGTGGAAACCAAGGCCGACGACTGTAAAGACGGCAAGTGCTGA