149326

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 826213..826867 Replicon chromosome
Accession NZ_CP048388
Organism Citrobacter portucalensis strain PNUCL1

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag GZH81_RS03970 Protein ID WP_003825515.1
Coordinates 826460..826867 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag GZH81_RS03965 Protein ID WP_003825514.1
Coordinates 826213..826479 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GZH81_RS03940 (821369) 821369..822802 - 1434 WP_212024920.1 6-phospho-beta-glucosidase BglA -
GZH81_RS03945 (822922) 822922..823650 - 729 WP_008785744.1 MurR/RpiR family transcriptional regulator -
GZH81_RS03950 (823703) 823703..824014 + 312 WP_008785743.1 N(4)-acetylcytidine aminohydrolase -
GZH81_RS03955 (824178) 824178..824840 + 663 WP_006686898.1 hemolysin III family protein -
GZH81_RS03960 (824972) 824972..825955 - 984 WP_008785741.1 tRNA-modifying protein YgfZ -
GZH81_RS03965 (826213) 826213..826479 + 267 WP_003825514.1 FAD assembly factor SdhE Antitoxin
GZH81_RS03970 (826460) 826460..826867 + 408 WP_003825515.1 protein YgfX Toxin
GZH81_RS03975 (826969) 826969..827490 - 522 WP_003026933.1 flavodoxin FldB -
GZH81_RS03980 (827604) 827604..828500 + 897 WP_212024923.1 site-specific tyrosine recombinase XerD -
GZH81_RS03985 (828524) 828524..829237 + 714 WP_048225463.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
GZH81_RS03990 (829243) 829243..830976 + 1734 WP_212024925.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15882.76 Da        Isoelectric Point: 11.3523

>T149326 WP_003825515.1 NZ_CP048388:826460-826867 [Citrobacter portucalensis]
VVQWQSDLRVSWRAQWLSLLIHGLVAVFILLMPWPLSYTPLWLVLLSLVVFDSVRSQRRINACQGEIRLLMDGRLRWQGQ
EWSIVSAPWMVKTGMMLRLRSDAGKRQHLWLAADSMDDAEWRDLRRLMLQKAKQG

Download         Length: 408 bp

>T149326 NZ_CP064002:786289-786441 [Xanthomonas translucens pv. translucens]
ATGAAGCGACTGTTCACCTTGACGATGCTGACCCTGTTTTGTGCAGGCATGCTGACCGGCTGCAACACCATGGCCGGCGC
CGGTAAGGACATGCAGAAGGCCGGCGATAAGGTGGAAACCAAGGCCGACGACTGTAAAGACGGCAAGTGCTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10615.14 Da        Isoelectric Point: 5.1700

>AT149326 WP_003825514.1 NZ_CP048388:826213-826479 [Citrobacter portucalensis]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFIRLLECDDPDLFNWLMNHGKPADEQLEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT149326 NZ_CP064002:786540-786674 [Xanthomonas translucens pv. translucens]
ATGAAGCGTACTTTCGCGTGGATGCTGCTGGCGATGTTCTCGGTGGGCCTGCTGTCGGGCTGCAACACGGTTGCCGGTGC
CGGCAAGGACGTGAAGAGCGCCGGCGAGAAGGTCGAAGACGCCGCCAAGAACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References