Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1997486..1997757 Replicon chromosome
Accession NZ_CP048376
Organism Escherichia coli strain 38

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1997616..1997719 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1997486..1997757 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GZS06_RS09495 1994041..1994703 - 663 WP_000944256.1 exodeoxyribonuclease X -
GZS06_RS09500 1994727..1995383 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
GZS06_RS09505 1995485..1995715 - 231 WP_000916763.1 DNA polymerase III subunit theta -
GZS06_RS09510 1995854..1996228 + 375 WP_000204699.1 CopC domain-containing protein YobA -
GZS06_RS09515 1996232..1997104 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
GZS06_RS09520 1997117..1997458 + 342 WP_000976492.1 YebY family protein -
- 1997486..1997757 - 272 - - Antitoxin
- 1997616..1997719 + 104 - - Toxin
GZS06_RS09525 1997854..1998510 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
GZS06_RS09530 1998511..1998702 - 192 WP_001296140.1 YebW family protein -
GZS06_RS09535 1998807..1999043 - 237 WP_001295499.1 DUF1480 family protein -
GZS06_RS09540 1999161..2000600 - 1440 WP_000057023.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1954573..2013595 59022


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T149285 NZ_CP048376:1997616-1997719 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT149285 NZ_CP048376:c1997757-1997486 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References