Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2007115..2007386 Replicon chromosome
Accession NZ_CP048344
Organism Escherichia coli strain 124

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2007245..2007348 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2007115..2007386 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GZS11_RS09580 2003670..2004332 - 663 WP_000944256.1 exodeoxyribonuclease X -
GZS11_RS09585 2004356..2005012 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
GZS11_RS09590 2005114..2005344 - 231 WP_000916763.1 DNA polymerase III subunit theta -
GZS11_RS09595 2005483..2005857 + 375 WP_000204699.1 CopC domain-containing protein YobA -
GZS11_RS09600 2005861..2006733 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
GZS11_RS09605 2006746..2007087 + 342 WP_000976492.1 YebY family protein -
- 2007115..2007386 - 272 - - Antitoxin
- 2007245..2007348 + 104 - - Toxin
GZS11_RS09610 2007483..2008139 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
GZS11_RS09615 2008140..2008331 - 192 WP_001296140.1 YebW family protein -
GZS11_RS09620 2008436..2008672 - 237 WP_001295499.1 DUF1480 family protein -
GZS11_RS09625 2008790..2010229 - 1440 WP_000057023.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T149151 NZ_CP048344:2007245-2007348 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT149151 NZ_CP048344:c2007386-2007115 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References