Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2153610..2153881 Replicon chromosome
Accession NZ_CP048337
Organism Escherichia coli strain 142

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2153740..2153843 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2153610..2153881 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GZS12_RS10045 2150165..2150827 - 663 WP_000944256.1 exodeoxyribonuclease X -
GZS12_RS10050 2150851..2151507 - 657 WP_000011651.1 carbon-nitrogen hydrolase family protein -
GZS12_RS10055 2151609..2151839 - 231 WP_000916763.1 DNA polymerase III subunit theta -
GZS12_RS10060 2151978..2152352 + 375 WP_022645803.1 CopC domain-containing protein YobA -
GZS12_RS10065 2152356..2153228 + 873 WP_022645802.1 copper homeostasis membrane protein CopD -
GZS12_RS10070 2153241..2153582 + 342 WP_000976472.1 YebY family protein -
- 2153610..2153881 - 272 - - Antitoxin
- 2153740..2153843 + 104 - - Toxin
GZS12_RS10075 2153978..2154634 + 657 WP_022645801.1 protein-serine/threonine phosphatase -
GZS12_RS10080 2154635..2154826 - 192 WP_001296140.1 YebW family protein -
GZS12_RS10085 2154931..2155167 - 237 WP_001295499.1 DUF1480 family protein -
GZS12_RS10090 2155285..2156724 - 1440 WP_024181822.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T149110 NZ_CP048337:2153740-2153843 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT149110 NZ_CP048337:c2153881-2153610 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References