Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-HTH_26
Location 256151..256753 Replicon chromosome
Accession NZ_CP048280
Organism Rhizobium leguminosarum bv. viciae 248

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GYN07_RS01300 Protein ID WP_020048405.1
Coordinates 256151..256396 (+) Length 82 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GYN07_RS01305 Protein ID WP_020048406.1
Coordinates 256406..256753 (+) Length 116 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GYN07_RS01260 251573..252004 + 432 WP_020048400.1 DUF2948 family protein -
GYN07_RS01265 252121..253419 + 1299 WP_020048401.1 histidinol dehydrogenase -
GYN07_RS01270 253424..253897 + 474 WP_020048402.1 UPF0262 family protein -
GYN07_RS01275 253894..254379 + 486 WP_018072487.1 low molecular weight phosphatase family protein -
GYN07_RS01280 254502..254720 + 219 WP_003545338.1 translation initiation factor IF-1 -
GYN07_RS01285 254778..255398 + 621 WP_020048403.1 Maf-like protein -
GYN07_RS01290 255431..255643 + 213 WP_020048404.1 DNA gyrase inhibitor YacG -
GYN07_RS01300 256151..256396 + 246 WP_020048405.1 cytotoxic translational repressor of toxin-antitoxin stability system Toxin
GYN07_RS01305 256406..256753 + 348 WP_020048406.1 helix-turn-helix transcriptional regulator Antitoxin
GYN07_RS01310 256915..257193 - 279 WP_003545380.1 transposase -
GYN07_RS01315 257201..258646 - 1446 WP_020048407.1 HlyD family type I secretion periplasmic adaptor subunit -
GYN07_RS01320 258661..260376 - 1716 WP_020048408.1 type I secretion system permease/ATPase -
GYN07_RS01325 260480..261055 - 576 WP_020048409.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(60-114)


Sequences

Toxin        


Download         Length: 82 a.a.        Molecular weight: 9018.59 Da        Isoelectric Point: 10.6821

>T148943 WP_020048405.1 NZ_CP048280:256151-256396 [Rhizobium leguminosarum bv. viciae 248]
MKKIAYSKAATKALRKMQPKRAAAIVAKVEAFANGETVDLKKLQGSEFFRIRVGQDRVIIDDQTLQVLVIKAGPRGDIYN
E

Download         Length: 246 bp

>T148943 NZ_CP063906:c4023733-4023515 [Klebsiella pneumoniae]
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAATAAATATGAACTGTCTGATAATGAGCTGGCGGTATTTTACTCAGCTGCCGACCATCGTCTGGCGGAAC
TGACCATGAATAAGCTATACGATAAAATTCCGACCTCTGTCTGGAAATTTATCCGCTAA

Antitoxin


Download         Length: 116 a.a.        Molecular weight: 12490.05 Da        Isoelectric Point: 4.3175

>AT148943 WP_020048406.1 NZ_CP048280:256406-256753 [Rhizobium leguminosarum bv. viciae 248]
MGEIQKLTIGGKGYVLLSEDDYQDLVDVSEARAAKARIDAGEETWPEDVVKALIAGEDPVRVFRKHRGMSIKELAEKSGL
SQPYLSEIETGKKEGSLDALRSIASALDVDLDDVA

Download         Length: 348 bp

>AT148943 NZ_CP063906:c4024134-4023760 [Klebsiella pneumoniae]
ATGGACGAATACTCGCCAAAAAGACATGATATTGCACAGCTACGCTTTCTCTGCGAAACGCTGTATCATGACTGCCTTGC
AAACCTGGAAGAGAGCAACCATGGCTGGGTCAACGACCCGACGTCGGCTGTCAATCTCCAGTTAAATGAATTGATCGAGC
ACATTGCCACATTCGCTCTTAATTATAAAATTAAGTATGCAGAGGATAATAAGCTGATCGCTCAGGTTGACGAATATCTG
GACGACACTTTTACGTTGTTCAGTAACTACGGCATTAACTCTACGGATTTGCAAAAGTGGAAAAAATCCGGTAACCGACT
ATTTCGTTGCTTTGTCAACGCCAGCCGGGAAAACCCGGCCAGTCTATCGTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References