148907

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1032720..1033255 Replicon chromosome
Accession NZ_CP048243
Organism Ewingella americana strain B6-1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GXP68_RS04825 Protein ID WP_185689427.1
Coordinates 1032720..1033007 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GXP68_RS04830 Protein ID WP_185689428.1
Coordinates 1033004..1033255 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GXP68_RS04805 1028481..1029364 + 884 Protein_939 DMT family transporter -
GXP68_RS04810 1029468..1030112 + 645 WP_034792307.1 adenylate kinase -
GXP68_RS04815 1030346..1031308 + 963 WP_185689425.1 ferrochelatase -
GXP68_RS04820 1031335..1032654 + 1320 WP_185689426.1 inosine/guanosine kinase -
GXP68_RS04825 1032720..1033007 - 288 WP_185689427.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GXP68_RS04830 1033004..1033255 - 252 WP_185689428.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
GXP68_RS04835 1033379..1034155 - 777 WP_034792301.1 SDR family oxidoreductase -
GXP68_RS04840 1034356..1035282 + 927 WP_185689429.1 LysR family transcriptional regulator -
GXP68_RS04845 1035469..1035813 + 345 WP_034792297.1 carboxymuconolactone decarboxylase family protein -
GXP68_RS04850 1035865..1036545 + 681 WP_185689430.1 cupin domain-containing protein -
GXP68_RS04855 1036542..1037666 + 1125 WP_185689431.1 FAD-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11043.95 Da        Isoelectric Point: 10.6276

>T148907 WP_185689427.1 NZ_CP048243:c1033007-1032720 [Ewingella americana]
MTYAVKFRESAFKEWNKLDKAVQQQFAKKLKKCSENPHIPSAKLRGLPNCYKIKLRASGFRLVYEVIDNQLIISVVAVGK
RERSEVYNLASERLR

Download         Length: 288 bp

>T148907 NZ_CP063900:c4366888-4366670 [Klebsiella quasipneumoniae]
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAACAAATATGAACTTTCTGATAATGAGCTGGCGGTATTTTACTCAGCCGCCGATCATCGTCTGGCTGAAC
TGACTATGAATAAGCTGTACGATAAAATCCCGACGTCCGTCTGGAAATTTATCCGCTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9121.38 Da        Isoelectric Point: 4.1789

>AT148907 WP_185689428.1 NZ_CP048243:c1033255-1033004 [Ewingella americana]
MPHAILSDTTASVSELKKNPMATVSAGAGYPVAILNRNQPAFYCIPAELYEKMLEALDDNELARLVGERQNQPLIDVDLD
SYL

Download         Length: 252 bp

>AT148907 NZ_CP063900:c4367289-4366915 [Klebsiella quasipneumoniae]
ATGGACGAATACTCGCCAAAAAGACATGATATCGCACAACTACGCTTTCTCTGCGAAACGCTGTATCATGACTGCCTTGC
AAACCTGGAAGAGAGCAACCATGGCTGGGTCAACGACCCGACATCGGCTGTCAATCTCCAGTTAAATGAACTGATCGAGC
ACATTGCCACATTCGCCCTTAATTATAAAATTAAGTACGCTGAGGATAATAAGCTGATCGCTCAGGTTGACGAATATCTG
GACGACACATTTACGTTGTTCAGTAACTACGGCATTAACTCTACGGATTTGCAAAAGTGGAAAAAATCCGGTAATCGGTT
ATTTCGTTGTTTTGTCAACGCCAGCCGGGAAAATCCGGCCAGTCTTTCGTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References