Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 760872..761040 Replicon chromosome
Accession NZ_CP048108
Organism Klebsiella michiganensis strain BD177

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 760930..761033 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 760872..761040 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GW952_RS03595 755999..758059 + 2061 WP_162121255.1 oligopeptidase B -
GW952_RS03600 758066..758725 - 660 WP_162121256.1 exodeoxyribonuclease X -
GW952_RS03605 758804..759034 - 231 WP_004103351.1 DNA polymerase III subunit theta -
GW952_RS03610 759170..759544 + 375 WP_160741056.1 CopC domain-containing protein YobA -
GW952_RS03615 759549..760418 + 870 WP_160741057.1 copper homeostasis membrane protein CopD -
GW952_RS03620 760435..760773 + 339 WP_162121257.1 YebY family protein -
- 760872..761040 - 169 - - Antitoxin
- 760930..761033 + 104 - - Toxin
GW952_RS03625 761669..761812 - 144 WP_009651986.1 Ecr family regulatory small membrane protein -
GW952_RS03630 761924..762868 - 945 WP_160741058.1 VirK/YbjX family protein -
GW952_RS03635 763033..763686 + 654 WP_160741059.1 protein-serine/threonine phosphatase -
GW952_RS03640 763683..763874 - 192 WP_004122014.1 YebW family protein -
GW952_RS03645 763972..764211 - 240 WP_004852069.1 YebV family protein -
GW952_RS03650 764327..765760 - 1434 WP_160741060.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T148872 NZ_CP048108:760930-761033 [Klebsiella michiganensis]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 169 bp

>AT148872 NZ_CP048108:c761040-760872 [Klebsiella michiganensis]
AACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGTCCGTGACAAAAGTG
GACGAATAA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References