Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4220555..4221074 Replicon chromosome
Accession NZ_CP048051
Organism Pseudomonas chlororaphis subsp. aurantiaca strain zm-1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GSF17_RS18920 Protein ID WP_162095625.1
Coordinates 4220555..4220836 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GSF17_RS18925 Protein ID WP_162095626.1
Coordinates 4220826..4221074 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GSF17_RS18895 4215828..4216100 + 273 WP_162095623.1 hypothetical protein -
GSF17_RS31255 4216859..4216987 - 129 Protein_3744 ATP-binding protein -
GSF17_RS18905 4217078..4217869 + 792 WP_162095624.1 methyltransferase domain-containing protein -
GSF17_RS18910 4218184..4218666 + 483 WP_009049637.1 acyl-CoA thioesterase -
GSF17_RS18915 4218723..4220372 + 1650 WP_124338633.1 FMN-binding glutamate synthase family protein -
GSF17_RS18920 4220555..4220836 - 282 WP_162095625.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GSF17_RS18925 4220826..4221074 - 249 WP_162095626.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
GSF17_RS18930 4221162..4221950 - 789 WP_162095627.1 helix-turn-helix transcriptional regulator -
GSF17_RS18935 4222035..4223033 + 999 WP_081360539.1 bile acid:sodium symporter -
GSF17_RS18940 4223248..4225011 + 1764 WP_162095628.1 hypothetical protein -
GSF17_RS18945 4225084..4225545 + 462 WP_009049642.1 YccF domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-81)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10849.64 Da        Isoelectric Point: 10.6282

>T148758 WP_162095625.1 NZ_CP048051:c4220836-4220555 [Pseudomonas chlororaphis subsp. aurantiaca]
MTYELEFSEKAWREWQKLGPTLKEQFKKKLQERLVNPHVPADRLSGLGNAYKIKLRTAGYRLVYRVVDEVLVVTVIAVGK
RERGSVYQQASKR

Download         Length: 282 bp

>T148758 NZ_CP063865:3821582-3821914 [Klebsiella pneumoniae]
ATGAAAACTTTACCTGCAACAACTCCGCAGACGGCGAAGCTATGTCTGACGTCCGCGGATACCTGGCAAATGTTACTGAC
ACGTCTGCTAGAACAGCATTATGGCCTGACACTGAACGACACGCCGTTCAGTGATGAAACTGTTATTAAGGAACATATTG
ATGCAGGGATCCCTCTGGCCGATGCAGTTAACTTTCTGGTGGATAAGTACGCACTGGTTCGTATCGATCGCAGAGGATTG
AGTTGGCAGGAGCAATCATCCTATCTCCGGCTTGTCGATACTCAGCGAACCATTAAGGTTATTGAGTTGTGGCTATTTGG
TGTAATGATGTAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8996.43 Da        Isoelectric Point: 4.7512

>AT148758 WP_162095626.1 NZ_CP048051:c4221074-4220826 [Pseudomonas chlororaphis subsp. aurantiaca]
MTHVLLSNVVASISELKKNPMGTVAAGGGSSVAILNRNEPAFYCVPAKEYEAMMERLEDMELLALCRERKNDPTIKVSLD
DL

Download         Length: 249 bp

>AT148758 NZ_CP063865:3821244-3821561 [Klebsiella pneumoniae]
ATGAGCAACATCACTTGGGGCCTGCAGCGGGATATCACGCCGTGCCTGGGATCACGTCTGGTGCAGGAGGGCAACCGGCT
GCACTATCTGGCTGACCGAGCAAGTATCACCGGTAAGTTTAGTGATGCCGAAAGCCTGAAGTTGGATGTCGTATTTCCAC
ATTTTATCAGTCAGATGGAATCGATGTTGACCACTGGTGAAATGAACCCTCGCCATGCCCACTGTGTCACCCTGTACCAC
AACGGTTTTACCTGCGAAGCCGATACTCTTGGTAGTTCCGGCTACGTATACATCGCTGTTTATCTCACCCAACGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References