Detailed information of TA system TA148755

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-StbC
• Location: 323284..323954
• Replicon: chromosome
• Accession: NZ_CP048051
• Organism: Pseudomonas chlororaphis subsp. aurantiaca strain zm-1

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: GSF17_RS01415
• Protein ID: WP_081362979.1
• Coordinates: 323284..323712 (-)
• Length: 143 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: GSF17_RS01420
• Protein ID: WP_162094241.1
• Coordinates: 323709..323954 (-)
• Length: 82 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GSF17_RS01400	318403..320661	+	2259	WP_162094240.1	TonB-dependent receptor	-
GSF17_RS01405	320708..322033	+	1326	WP_081362981.1	LLM class flavin-dependent oxidoreductase	-
GSF17_RS01410	322118..323155	+	1038	WP_016702559.1	L-glyceraldehyde 3-phosphate reductase	-
GSF17_RS01415	323284..323712	-	429	WP_081362979.1	type II toxin-antitoxin system VapC family toxin	Toxin
GSF17_RS01420	323709..323954	-	246	WP_162094241.1	plasmid stabilization protein	Antitoxin
GSF17_RS01425	324094..324933	-	840	WP_162094242.1	taurine dioxygenase	-
GSF17_RS01430	325170..326009	-	840	WP_009046455.1	taurine ABC transporter permease TauC	-
GSF17_RS01435	326006..326800	-	795	WP_023970012.1	taurine ABC transporter ATP-binding subunit	-
GSF17_RS01440	326896..327873	-	978	WP_124307429.1	taurine ABC transporter substrate-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (2-124)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 143 a.a.
• Molecular weight: 15853.36 Da
• Isoelectric Point: 5.4927

>T148755 WP_081362979.1 NZ_CP048051:c323712-323284 [Pseudomonas chlororaphis subsp. aurantiaca]
MIVLDTNVLSELMRPQPDTAVLLWIEAQPVEDLYISAMTMAEILHGIARLPHGKRKQTLHASAVAMFEEDFIDRIVPFGT
QAALYYAHLVSHRERSGQPINLVDAQIAAICRVHDAAIATRNTKDFTDTGLIVINPWLPLEV

Nucleotide

• Length: 429 bp

>T148755 NZ_CP063865:3248961-3249344 [Klebsiella pneumoniae]
ATGACCTCCGGATCTGCGCTTTTTGATACCAATATTCTTATTGATTTATTTAGCGGGCGTCGCGAAGCCAAACAGGCGCT
GGAGGCCTGGCCACCGCAGAATGCGATCAGTCTGATTACCTGGATGGAGGTGATGGTTGGCGCTAAAAAATATCACCAGG
AGCAGCGCACGCGAATGGCGCTGAGCACCTTTAATATCATTAACATCTCACAGGATATTGCAGAGCGAAGCGTTGCGCTG
CGGCAGGAGTATAAGCTTAAGCTGCCGGATGCCATCATTCTGGCGACGGCGCAACTCCATCGTCTGGAACTAATTACGCG
GAATACGAAGGATTTTACCGGTATTCCTGGCGTAGTCACGCCGTACGAAATCCACCCTGAATAA

Antitoxin

Protein

• Length: 82 a.a.
• Molecular weight: 9128.41 Da
• Isoelectric Point: 7.3226

>AT148755 WP_162094241.1 NZ_CP048051:c323954-323709 [Pseudomonas chlororaphis subsp. aurantiaca]
MASLTIRNLDDHIKERLRIKAAHNGHSMEEEARLILRRALIRTADSQGLGSRIRARFAETGGVELELPERTEPARLVDLG
E

Nucleotide

• Length: 246 bp

>AT148755 NZ_CP063865:3248719-3248961 [Klebsiella pneumoniae]
ATGATGGCTGAAAGGGATATGGGCAGAATTCTTCTCGATTTATCAGACGATGTCATTCAACGTCTCGATGACCTCAAAGT
GCAGCGTAACATTCCGCGAGCGGAACTGTTACGTGAAGCGGTTGAACAATATCTGGAGAAACAAGATCGAGCTAAAGATA
CCATCTCCAGTGCGCTGGGTCTGTGGCAAGACTGCGAAGAAGACGGCATGGAATATCAACGTCAGCTACGCAAGGAGTGG
TAA