148753

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4680567..4680928 Replicon chromosome
Accession NZ_CP048044
Organism Xanthomonas citri strain UnB-Xtec2D

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag FYK61_RS19915 Protein ID WP_005914328.1
Coordinates 4680567..4680701 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag FYK61_RS19920 Protein ID WP_003486606.1
Coordinates 4680776..4680928 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FYK61_RS19900 4677597..4678640 - 1044 WP_194272002.1 MBL fold metallo-hydrolase -
FYK61_RS19905 4678670..4679959 - 1290 WP_194272003.1 tryptophan--tRNA ligase -
FYK61_RS19910 4680132..4680341 - 210 WP_016904514.1 CsbD family protein -
FYK61_RS19915 4680567..4680701 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
FYK61_RS19920 4680776..4680928 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
FYK61_RS19925 4681035..4681958 - 924 WP_007966941.1 arginase -
FYK61_RS19930 4682279..4682731 + 453 WP_007974175.1 roadblock/LC7 domain-containing protein -
FYK61_RS19935 4682795..4683154 + 360 WP_003486613.1 hypothetical protein -
FYK61_RS19940 4683251..4684168 + 918 WP_089096274.1 hypothetical protein -
FYK61_RS19945 4684165..4684707 + 543 WP_003486615.1 GTPase -
FYK61_RS19950 4685187..4685870 + 684 WP_007966938.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T148753 WP_005914328.1 NZ_CP048044:c4680701-4680567 [Xanthomonas citri]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T148753 NZ_CP063865:c2821101-2820754 [Klebsiella pneumoniae]
ATGTGGGATGTAGAAACGACGGATACGTTTGATACCTGGTTCGAATTACAAAGTAGAGCTTTAAAAGAGGATATGTTGGC
CACGATGCTCATCCTGTCTGAGTTTGCTCCGCAGCTTGGGCGCCCGTATGTTGATACGGTGAAAGATTCAACGTTTCAGA
ATATGAAAGAACTGCGGGTTCAGCATCATGGGCTCCCCATCCGCGCCTTTTTTGCTTTTGATCCTCTGCGGAAAGCTATC
GTTTTATGTGCGGGCAATAAGGATGGCATGAATGAGAAACGTTTTTACAAAGAGATGATTACTCTGGCTGACAGAGAATT
CAGCCAACACCTGACTAAGGAGCGATAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT148753 WP_003486606.1 NZ_CP048044:c4680928-4680776 [Xanthomonas citri]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT148753 NZ_CP063865:c2820754-2820455 [Klebsiella pneumoniae]
ATGGCCACGCTAAAAGAACTCATGGCGAAACAGAGTCCTGATAGCCAGCAGCGTATTGCAGCGAAAGCGGCAGAGATACG
CCAGTCTGTCGCTTTAAACTTGCTTCGAGAAGAGTTGCAAATGTCGCAAACAGAGATGGCTGCGGCTATGGGGGTAAAGC
AGCCAACGATCGCTAAAATGGAACAGGCTGATAACGACCCTCGGCTTTCGACCCTAAAACGCTACATTGCGGCATGGGGG
GGAGAACTCAGTATAAATGTCACATTGCCGACTGGAAAAAAAGTCTCGTTTAATTTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References