Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 3185282..3185835 Replicon chromosome
Accession NZ_CP048030
Organism Sinimarinibacterium sp. NLF-5-8

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GT972_RS15145 Protein ID WP_162079368.1
Coordinates 3185542..3185835 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GT972_RS15140 Protein ID WP_162079367.1
Coordinates 3185282..3185554 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GT972_RS15115 3180466..3181395 + 930 WP_162079362.1 glycosyltransferase family 2 protein -
GT972_RS15120 3181397..3182587 - 1191 WP_162079363.1 DUF2029 domain-containing protein -
GT972_RS15125 3182591..3183751 - 1161 WP_162079364.1 hypothetical protein -
GT972_RS15130 3183872..3184108 + 237 WP_162079365.1 hypothetical protein -
GT972_RS15135 3184346..3184723 - 378 WP_162079366.1 GtrA family protein -
GT972_RS15140 3185282..3185554 + 273 WP_162079367.1 CopG family ribbon-helix-helix protein Antitoxin
GT972_RS15145 3185542..3185835 + 294 WP_162079368.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GT972_RS15150 3186202..3187416 - 1215 WP_162079369.1 SufS family cysteine desulfurase -
GT972_RS15155 3187413..3188624 - 1212 WP_162079370.1 Fe-S cluster assembly protein SufD -
GT972_RS15160 3188624..3189373 - 750 WP_162079371.1 Fe-S cluster assembly ATPase SufC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-95)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-40)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10782.28 Da        Isoelectric Point: 5.1311

>T148745 WP_162079368.1 NZ_CP048030:3185542-3185835 [Sinimarinibacterium sp. NLF-5-8]
VPQVIVTEGAADGLERCRRFLAVKAPDAARRAGQAIERQFLMLETAPDIGRPFPEMPELRELVVAFGDSGYVALYHHEPA
DDAVYVLAFRHQKEAGY

Download         Length: 294 bp

>T148745 NZ_CP063863:2342553-2342963 [Klebsiella pneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCG
TGCGCAGCCAGCGGCGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCC
GAATGGGAGATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATACCCGGCGCGG
ACAGCATCTTTGGCTGGCGGCGGACAGCATGGATGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGG
CGCAGGAGTAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10546.88 Da        Isoelectric Point: 9.0711

>AT148745 WP_162079367.1 NZ_CP048030:3185282-3185554 [Sinimarinibacterium sp. NLF-5-8]
MATSLKIDDTLKGRVQHLASQRRRSPHWIMLEAIRQYVEREEARESFGQEALAAWAAYKETGRHLTGQEVRTWLNTWGTR
DERAVPECHK

Download         Length: 273 bp

>AT148745 NZ_CP063863:2342306-2342572 [Klebsiella pneumoniae]
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References