Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 3185282..3185835 Replicon chromosome
Accession NZ_CP048030
Organism Sinimarinibacterium sp. NLF-5-8

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GT972_RS15145 Protein ID WP_162079368.1
Coordinates 3185542..3185835 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GT972_RS15140 Protein ID WP_162079367.1
Coordinates 3185282..3185554 (+) Length 91 a.a.

Genomic Context

GT972_RS15115GT972_RS15130GT972_RS15140GT972_RS15145GT972_RS15120GT972_RS15125GT972_RS15135GT972_RS15150GT972_RS15155GT972_RS15160
Location: 3180466..3181395 (930 bp)
Type: Others
Protein ID: WP_162079362.1
Location: 3183872..3184108 (237 bp)
Type: Others
Protein ID: WP_162079365.1
Location: 3185282..3185554 (273 bp)
Type: Antitoxin
Protein ID: WP_162079367.1
Location: 3185542..3185835 (294 bp)
Type: Toxin
Protein ID: WP_162079368.1
Location: 3181397..3182587 (1191 bp)
Type: Others
Protein ID: WP_162079363.1
Location: 3182591..3183751 (1161 bp)
Type: Others
Protein ID: WP_162079364.1
Location: 3184346..3184723 (378 bp)
Type: Others
Protein ID: WP_162079366.1
Location: 3186202..3187416 (1215 bp)
Type: Others
Protein ID: WP_162079369.1
Location: 3187413..3188624 (1212 bp)
Type: Others
Protein ID: WP_162079370.1
Location: 3188624..3189373 (750 bp)
Type: Others
Protein ID: WP_162079371.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
GT972_RS151153180466..3181395+930WP_162079362.1glycosyltransferase family 2 protein-
GT972_RS151203181397..3182587-1191WP_162079363.1DUF2029 domain-containing protein-
GT972_RS151253182591..3183751-1161WP_162079364.1hypothetical protein-
GT972_RS151303183872..3184108+237WP_162079365.1hypothetical protein-
GT972_RS151353184346..3184723-378WP_162079366.1GtrA family protein-
GT972_RS151403185282..3185554+273WP_162079367.1CopG family ribbon-helix-helix proteinAntitoxin
GT972_RS151453185542..3185835+294WP_162079368.1type II toxin-antitoxin system RelE/ParE family toxinToxin
GT972_RS151503186202..3187416-1215WP_162079369.1SufS family cysteine desulfurase-
GT972_RS151553187413..3188624-1212WP_162079370.1Fe-S cluster assembly protein SufD-
GT972_RS151603188624..3189373-750WP_162079371.1Fe-S cluster assembly ATPase SufC-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-95)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-40)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10782.28 Da        Isoelectric Point: 5.1311

>T148745 WP_162079368.1 NZ_CP048030:3185542-3185835 [Sinimarinibacterium sp. NLF-5-8]
VPQVIVTEGAADGLERCRRFLAVKAPDAARRAGQAIERQFLMLETAPDIGRPFPEMPELRELVVAFGDSGYVALYHHEPA
DDAVYVLAFRHQKEAGY

Download         Length: 294 bp

>T148745 NZ_CP063863:2342553-2342963 [Klebsiella pneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCG
TGCGCAGCCAGCGGCGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCC
GAATGGGAGATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATACCCGGCGCGG
ACAGCATCTTTGGCTGGCGGCGGACAGCATGGATGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGG
CGCAGGAGTAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10546.88 Da        Isoelectric Point: 9.0711

>AT148745 WP_162079367.1 NZ_CP048030:3185282-3185554 [Sinimarinibacterium sp. NLF-5-8]
MATSLKIDDTLKGRVQHLASQRRRSPHWIMLEAIRQYVEREEARESFGQEALAAWAAYKETGRHLTGQEVRTWLNTWGTR
DERAVPECHK

Download         Length: 273 bp

>AT148745 NZ_CP063863:2342306-2342572 [Klebsiella pneumoniae]
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References