Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 159984..160509 Replicon chromosome
Accession NZ_CP048029
Organism Caldichromatium japonicum strain No.7

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GWK36_RS00760 Protein ID WP_166269231.1
Coordinates 159984..160262 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag GWK36_RS00765 Protein ID WP_166269233.1
Coordinates 160252..160509 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GWK36_RS00720 (GWK36_00715) 155149..155493 - 345 WP_166268949.1 hypothetical protein -
GWK36_RS00725 (GWK36_00720) 155579..156109 - 531 WP_166269221.1 hypothetical protein -
GWK36_RS00730 (GWK36_00725) 156248..156406 - 159 WP_166269223.1 hypothetical protein -
GWK36_RS00735 (GWK36_00730) 156393..156767 - 375 WP_166269225.1 hypothetical protein -
GWK36_RS00740 (GWK36_00735) 156769..157137 + 369 WP_166269227.1 hypothetical protein -
GWK36_RS00745 (GWK36_00740) 157107..157649 - 543 WP_210756811.1 DUF3489 domain-containing protein -
GWK36_RS00750 (GWK36_00745) 157755..158006 - 252 WP_166269229.1 hypothetical protein -
GWK36_RS15155 (GWK36_00750) 158218..159974 + 1757 Protein_154 phage terminase large subunit family protein -
GWK36_RS00760 (GWK36_00755) 159984..160262 - 279 WP_166269231.1 Txe/YoeB family addiction module toxin Toxin
GWK36_RS00765 (GWK36_00760) 160252..160509 - 258 WP_166269233.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
GWK36_RS00770 (GWK36_00765) 160588..160800 + 213 WP_166269235.1 hypothetical protein -
GWK36_RS00775 (GWK36_00770) 160800..161051 + 252 WP_210756814.1 phage portal protein -
GWK36_RS00780 (GWK36_00775) 161315..162553 - 1239 Protein_159 IS1182 family transposase -
GWK36_RS00785 (GWK36_00780) 162790..163602 + 813 WP_166269237.1 SDR family oxidoreductase -
GWK36_RS00795 (GWK36_00790) 163851..164948 + 1098 Protein_161 IS3 family transposase -
GWK36_RS00800 (GWK36_00795) 164989..165309 + 321 WP_246237871.1 major capsid protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(9-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 11008.66 Da        Isoelectric Point: 7.2126

>T148740 WP_166269231.1 NZ_CP048029:c160262-159984 [Caldichromatium japonicum]
MPIEDKLLKLTWTLAAWDDYEYWQGQDRKTLKRINALIKDCLRHPFEGVGKPEPLKENLSGFWSRRIDDTHRLVYCVDEQ
ALVVIACRYHYQ

Download         Length: 279 bp

>T148740 NZ_CP063863:c1145459-1144542 [Klebsiella pneumoniae]
ATGGATATACAGGCGCCTTATTATCGGCAGGTTGCTCTGCTAATGCAGGTTTTACCCTATGTTGCTGTCGAACGGGAATT
TGCGCTGAAAGGTGGCACTGCAATCAATCTCTTTATCCGCGATTTCCCTCGATTATCGGTGGATATCGACCTCGCCTGGG
TGCCCCTGGAAAGCAGAGCCATCGCTTTACCTCATATACGGGATGCGCTTGCACGTATTGCCGCCAATCTGCAACAACAG
GCAGGTATGAGCGCTGTATTACAAGCTAATCGTTCAGATGAGATGCGTGTCATTGTTACTACCGATAGCGCGCAAATAAA
GATAGAGGTTTCACCGGTCGCCCGGGGAACATTATATCCACCACAGGAGCGAGAAGTGGTGGGGGCGGTAGAGGACGTTT
TTGGCTATGCCAGCCTTCCAGTGGTTTCGTTGCCTGACCTCTACGGTGGAAAATTATGCGCGGCGCTGGATCGCCAGCAT
CCCAGAGATTTTTATGACGTGAAATTACTTCTTGATGCGCAGGAGCTTGACCGTCCCATTTTCAATGGGTTTATCGCGTA
TTTACTGAGCCATAATCGGCCTCTGGCTGAAGTGCTGAGTCCTCGCTGGAAAGATATTGCTGAACCTTTTTACCGTGAAT
TCAGCGGGATGACATTTGAGACGATAGCCCTGGAGGAACTGACAGCAGTCCCCAACAGGATGATTGCTGCGTTAAAATCC
TGTTTCACACAACAGGATGTCGATTTTTTACTGTCATTTAAACGAGGCGAACCAGACTGGCGTTTAGCGCCGGAAATGCG
TATTCAGGATTTGCCTGCCGTGCAGTGGAAATTGCGCAATATTCATCAGATGCCAGCGATAAAACGCGCTGAGTCATTAG
ATAAACTGGAAAAGGTGCTGGCCGAGTGGCGCAGTTAG

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9526.79 Da        Isoelectric Point: 5.6448

>AT148740 WP_166269233.1 NZ_CP048029:c160509-160252 [Caldichromatium japonicum]
MRVVNFSEARNNLKKVIDQVIDDADYTVIARRDAPDAVVMSLDTFNGLMETVHLLKSPANAAHLARSIDQYRQGKVKQQD
LVDAD

Download         Length: 258 bp

>AT148740 NZ_CP063863:c1146223-1145465 [Klebsiella pneumoniae]
ATGGCAACAAAATTAAACTGGCTGCTGCAAAACAGCGCTCCCGGAGATGTGATCCTTCAGTCCTGGTTAAGCCAGCATGC
CATCTCTCCCTCTCTGGCCTTTAAATACGCGCAAAGTGGCTGGTTAAAAAAAAGAGGCAACGGCGTATATGCGCGTGCGG
GACGTGAGCCGGAGTGGAACGATGCATTAGCATGTTTGCAAAATCAGCTTGCCGCTCCGGTGTATGTTGCGGGGCTCAGT
AGCTTAGTCTGGCAGGGCCGTTCACACTATCTACAGCTAAAACAAAGCCAGTGCTGGCTTAGTGTGGAAAATAAAGCGCT
GCTGCCGAAATGGTTCAGGGAATTCCCGGGTGTGGAGTGGATAGTCATATCGGGGAAAAAACTGCCGGTGCTGGATGATA
GATACCGTGTAACGCTTGATATAAAAGGGAAAAAACTCATCGGCAGTGCGCCAGAACTGGCTGCTTACGAGTTGCTGAGC
GCGGTGCCGGGGACCCTCTCATTTAACCACGCTGCAGAGCTTTTCCAGGGGCTGGTTAATCTTAATCCTCGTAAAGTAGA
GTATCTTCTTTCCGTCAGCCAGTCCGTGCAGGCCAAGCGTTTGTATCTCTTCTTCGCCAGTTTTTACGAGCATGGCTGGC
TCAAACGAATCGATAGCCAAAAAATCGATCTGGGAGCGGGCAAGCGGCAAATCGTGGAAAATGGAAAGTTCAATGCTCAA
TACCAAATCACAGTGCCTGAACGCTTTCAAAAGGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References