Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2028904..2029175 Replicon chromosome
Accession NZ_CP048010
Organism Escherichia coli strain RUT3575

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2029034..2029137 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2028904..2029175 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GW576_RS10000 2025459..2026121 - 663 WP_000944256.1 exodeoxyribonuclease X -
GW576_RS10005 2026145..2026801 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
GW576_RS10010 2026903..2027133 - 231 WP_000916763.1 DNA polymerase III subunit theta -
GW576_RS10015 2027272..2027646 + 375 WP_000204699.1 CopC domain-containing protein YobA -
GW576_RS10020 2027650..2028522 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
GW576_RS10025 2028535..2028876 + 342 WP_000976492.1 YebY family protein -
- 2028904..2029175 - 272 - - Antitoxin
- 2029034..2029137 + 104 - - Toxin
GW576_RS10030 2029272..2029928 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
GW576_RS10035 2029929..2030120 - 192 WP_001296140.1 YebW family protein -
GW576_RS10040 2030225..2030461 - 237 WP_001295499.1 DUF1480 family protein -
GW576_RS10045 2030579..2032018 - 1440 WP_000057023.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T148668 NZ_CP048010:2029034-2029137 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT148668 NZ_CP048010:c2029175-2028904 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References