148614

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 2531162..2531482 Replicon chromosome
Accession NZ_CP047970
Organism Cobetia pacifica strain GPM2

Toxin (Protein)


Gene name EcnB Uniprot ID -
Locus tag FX986_RS10660 Protein ID WP_077378694.1
Coordinates 2531351..2531482 (+) Length 44 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID -
Locus tag FX986_RS10655 Protein ID WP_077378691.1
Coordinates 2531162..2531293 (+) Length 44 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FX986_RS10640 2526812..2528992 + 2181 WP_191236496.1 TRAP transporter permease -
FX986_RS10645 2529178..2529957 + 780 WP_191236497.1 TSUP family transporter -
FX986_RS10650 2530101..2531096 + 996 WP_084209433.1 zinc-dependent alcohol dehydrogenase family protein -
FX986_RS10655 2531162..2531293 + 132 WP_077378691.1 entericidin A/B family lipoprotein Antitoxin
FX986_RS10660 2531351..2531482 + 132 WP_077378694.1 entericidin A/B family lipoprotein Toxin
FX986_RS10665 2531635..2531766 + 132 WP_077378697.1 entericidin A/B family lipoprotein -
FX986_RS10670 2531962..2532849 + 888 WP_077378700.1 LysR family transcriptional regulator -
FX986_RS10675 2532924..2533997 - 1074 WP_084209430.1 rhodanese-related sulfurtransferase -
FX986_RS10680 2534313..2535089 + 777 WP_191236498.1 formate dehydrogenase accessory sulfurtransferase FdhD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 44 a.a.        Molecular weight: 4597.30 Da        Isoelectric Point: 4.1319

>T148614 WP_077378694.1 NZ_CP047970:2531351-2531482 [Cobetia pacifica]
MRRFMMMTGTALLFGLMLGGCNTVEGFGEDLEHLGGSIEESAS

Download         Length: 132 bp

>T148614 NZ_CP063804:c2182104-2181775 [Mycobacterium orygis]
GTGACCGCACTTCCGGCGCGCGGAGAGGTGTGGTGGTGTGAGATGGCTGAGATCGGTCGGCGACCAGTCGTCGTGCTGTC
GCGCGATGCCGCGATCCCTCGGCTGCGACGCGCACTTGTCGCGCCCTGCACCACGACCATCCGAGGGCTAGCCAGTGAGG
TTGTTCTTGAACCCGGTTCCGACCCGATCCCGCGCCGTTCCGCGGTGAATTTGGACTCAGTCGAAAGTGTCTCGGTCGCG
GTATTGGTGAATCGGCTTGGCCGCCTCGCCGACATCCGGATGCGCGCCATCTGCACGGCCCTCGAGGTCGCCGTCGATTG
CTCTCGATGA

Antitoxin


Download         Length: 44 a.a.        Molecular weight: 4404.20 Da        Isoelectric Point: 8.0302

>AT148614 WP_077378691.1 NZ_CP047970:2531162-2531293 [Cobetia pacifica]
MRVTRLMMAALLVASVALTGCNTVAGFGKDLEHLGGKIDNAAS

Download         Length: 132 bp

>AT148614 NZ_CP063804:c2182478-2182101 [Mycobacterium orygis]
GTGAAGACGGCCCGGTTGCAGGTGACGTTGCGCTGCGCGGTAGACCTCATCAATTCGTCCAGCGACCAATGTTTCGCCCG
TATCGAGCACGTTGCGTCCGATCAGGCGGATCCACGCCCCGGAGTGTGGCATAGTAGTGGCATGAATCGCATACGGCTGA
GCACTACTGTCGACGCCGCACTCTTGACAAGTGCGCGCGACATGCGGGCAGGAATCACTGACGCAGCCCTCATCGATGAG
GCCCTTGCGGCATTACTGGCTCGTCATCGATCGGCCGAGGTGGATGCCAGCTATGCGGCCTACGACAAGCACCCGGTCGA
TGAGCCCGACGAGTGGGGCGATCTAGCGTCGTGGCGGCGGGCGGCTGGAGACTCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References