148585

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) PhoH-LOG/-
Location 1167117..1169410 Replicon chromosome
Accession NZ_CP047961
Organism Synechococcus sp. PROS-9-1

Toxin (Protein)


Gene name PhoH Uniprot ID -
Locus tag SynPROS91_RS06155 Protein ID WP_186515651.1
Coordinates 1167117..1168505 (+) Length 463 a.a.

Antitoxin (Protein)


Gene name LOG Uniprot ID -
Locus tag SynPROS91_RS06160 Protein ID WP_186519542.1
Coordinates 1168520..1169410 (+) Length 297 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SynPROS91_RS06130 1162856..1163236 + 381 WP_186515647.1 hypothetical protein -
SynPROS91_RS06135 1163316..1163816 - 501 Protein_1189 phosphoesterase -
SynPROS91_RS06140 1163986..1164615 + 630 WP_186515648.1 CAAD domain-containing protein -
SynPROS91_RS06145 1164761..1165330 - 570 WP_186515649.1 hypothetical protein -
SynPROS91_RS06150 1165585..1166859 - 1275 WP_186515650.1 cytochrome P450 -
SynPROS91_RS06155 1167117..1168505 + 1389 WP_186515651.1 PhoH family protein Toxin
SynPROS91_RS06160 1168520..1169410 + 891 WP_186519542.1 LOG family protein Antitoxin
SynPROS91_RS06165 1169599..1169742 - 144 WP_186515652.1 hypothetical protein -
SynPROS91_RS06170 1170038..1170271 - 234 WP_186515653.1 DUF3136 domain-containing protein -
SynPROS91_RS06175 1170794..1171774 + 981 WP_186519544.1 phosphate ABC transporter substrate-binding protein PstS -
SynPROS91_RS06180 1171949..1173136 + 1188 WP_186515654.1 chromate efflux transporter -
SynPROS91_RS06185 1173289..1174242 + 954 WP_186519546.1 esterase-like activity of phytase family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(239-448)

Antitoxin

(160-289)


Sequences


Toxin        


Download         Length: 463 a.a.        Molecular weight: 50616.61 Da        Isoelectric Point: 5.6889

>T148585 WP_186515651.1 NZ_CP047961:1167117-1168505 [Synechococcus sp. PROS-9-1]
MNKKVVVLDTNVLLHDPEAPSSFGSDRIVLPIQVIEEIDRFKRDPSEKGRNSRRIARLLDSLRERGNLADGVPLTPNSDG
TLEVAFCRAETLAQLPPELRGGGGDNNILAVALEQMRAKGLSEAPEVVLITKDTNLRIKADAVGLAAQDYANDKVAISDL
YPGARGVKVSADLIDELHQNGRLSLKALPTETVASLQPNEGVTLIDRDSSDHTFLARQHGDSGELEPLVWLKRARLGRLK
PRNREQNFALDLLLDPSVELVTLVGKAGTGKTLLAIAAGLHQVADEHRYARLLVTRPPISLGKEIGFLPGTLDEKLAPWM
QPIVDNLDFLTGDAMSNEQKDDRRRHGGGPKSSWSDLREMGLLEVEAINYIRGRSIPHQFMVVDEAQNLTPHEVKTIVTR
VGEGTKIVFTGDPYQIDNPYVDAESNGLTWLAERLKGQALVGHMTLTRGERSALAELAANML

Download         Length: 1389 bp

>T148585 NZ_CP063789:c35271-34753 [Tolypothrix sp. PCC 7712]
GTGACAGGCTCTCAAGAACAACAAATTCAGGCTCCAGAACCTCTCAATGCCGAGCATCAATTAGAAAACTTTGATTCCGG
TAATGCCGAACTGGATGAGTGGTTAAAAAAACGTGCTTTGAAAAACGAAGCTAGCGGAGCTTCCAGAACTTACGTGGTAA
CGGTGGGTCAGAAAGCGATCGCCTATTATTGTTTAGCAAATGGCAGTGTCATCAATACCACCGCTCCTGGTAAAGTCCGG
CGCAATATGCCAGACCCGATTCCCGTGATGGTCATTGGTCGGCTGGCGGTAGATATTAATTGGCAAGGGCAAGGTCTTGG
GTATGCTCTAGTGCGTGATGCAGTGCTTCGTACCCTCCAGGCAGCAAAGATTGCCGGAATCAGGGCGATTCTTGTTCATG
CCATTTCTGTTGAAGCGAAGCAGTTCTATGAGAAATGCGGTTTTATCCCCTCACCTGTTGCGCCGATGACCCTCATGGTA
ACGATCGCAGATGCGCTACAAGCGTTTGGAGTTGGGTAG

Antitoxin


Download         Length: 297 a.a.        Molecular weight: 32577.87 Da        Isoelectric Point: 4.6048

>AT148585 WP_186519542.1 NZ_CP047961:1168520-1169410 [Synechococcus sp. PROS-9-1]
MTSNIMDPGLPSDDPARVAGNLEQIIHSDNYRLAHQDLDLLNSSSMRGVRMLLEISKPELYFAEAGITSTIIVFGGARLQ
EKSAAEASLKEAIRELDADPDSTAWKRKVSRARKMLELSSFYDAAREFAFLASHFGQSGSNSGPCCSSHVIVTGGGPGIM
EAANRGAFDAGCRSIGLNIELPNEQNPNPYITPDLCFKFNYFALRKFHFVMRAVGAVLFPGGYGTLDELFELLTLRQVGT
QHAMPIVLFGKDYWSRLVDFEFMADSGLIDDEDLQLIQFADTAAEAWDLIRECSSS

Download         Length: 891 bp

>AT148585 NZ_CP063789:c35583-35275 [Tolypothrix sp. PCC 7712]
ATGCAGCCCCAAACAGGATCGTCCAACCATCAAAACCGTGATGTCACTATCAACATCAGGGCACACCAGGGACAACGGGA
TTTAATTGACCGAGCAGCAGAAGCCCTGGGCAAGAACCGTTCCGATTTCATGCTGGAGACCGCCTGTCGAGAAGCAGAAG
CAGTTTTGCTAGATCGGCGGCTGTTTATGCTGGATGATGAAAAGTTTCAGCAATTTGTCGAATTACTGGATCAGCCACCT
GCCACCAATGCCAACCTCCGGAAGTTGCTCACCAAGAAAGCACCTTGGGAACAGGGCGTGGGGGAGTAG

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References