Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | PhoH-LOG/- |
Location | 1167117..1169410 | Replicon | chromosome |
Accession | NZ_CP047961 | ||
Organism | Synechococcus sp. PROS-9-1 |
Toxin (Protein)
Gene name | PhoH | Uniprot ID | - |
Locus tag | SynPROS91_RS06155 | Protein ID | WP_186515651.1 |
Coordinates | 1167117..1168505 (+) | Length | 463 a.a. |
Antitoxin (Protein)
Gene name | LOG | Uniprot ID | - |
Locus tag | SynPROS91_RS06160 | Protein ID | WP_186519542.1 |
Coordinates | 1168520..1169410 (+) | Length | 297 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
SynPROS91_RS06130 | 1162856..1163236 | + | 381 | WP_186515647.1 | hypothetical protein | - |
SynPROS91_RS06135 | 1163316..1163816 | - | 501 | Protein_1189 | phosphoesterase | - |
SynPROS91_RS06140 | 1163986..1164615 | + | 630 | WP_186515648.1 | CAAD domain-containing protein | - |
SynPROS91_RS06145 | 1164761..1165330 | - | 570 | WP_186515649.1 | hypothetical protein | - |
SynPROS91_RS06150 | 1165585..1166859 | - | 1275 | WP_186515650.1 | cytochrome P450 | - |
SynPROS91_RS06155 | 1167117..1168505 | + | 1389 | WP_186515651.1 | PhoH family protein | Toxin |
SynPROS91_RS06160 | 1168520..1169410 | + | 891 | WP_186519542.1 | LOG family protein | Antitoxin |
SynPROS91_RS06165 | 1169599..1169742 | - | 144 | WP_186515652.1 | hypothetical protein | - |
SynPROS91_RS06170 | 1170038..1170271 | - | 234 | WP_186515653.1 | DUF3136 domain-containing protein | - |
SynPROS91_RS06175 | 1170794..1171774 | + | 981 | WP_186519544.1 | phosphate ABC transporter substrate-binding protein PstS | - |
SynPROS91_RS06180 | 1171949..1173136 | + | 1188 | WP_186515654.1 | chromate efflux transporter | - |
SynPROS91_RS06185 | 1173289..1174242 | + | 954 | WP_186519546.1 | esterase-like activity of phytase family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 463 a.a. Molecular weight: 50616.61 Da Isoelectric Point: 5.6889
>T148585 WP_186515651.1 NZ_CP047961:1167117-1168505 [Synechococcus sp. PROS-9-1]
MNKKVVVLDTNVLLHDPEAPSSFGSDRIVLPIQVIEEIDRFKRDPSEKGRNSRRIARLLDSLRERGNLADGVPLTPNSDG
TLEVAFCRAETLAQLPPELRGGGGDNNILAVALEQMRAKGLSEAPEVVLITKDTNLRIKADAVGLAAQDYANDKVAISDL
YPGARGVKVSADLIDELHQNGRLSLKALPTETVASLQPNEGVTLIDRDSSDHTFLARQHGDSGELEPLVWLKRARLGRLK
PRNREQNFALDLLLDPSVELVTLVGKAGTGKTLLAIAAGLHQVADEHRYARLLVTRPPISLGKEIGFLPGTLDEKLAPWM
QPIVDNLDFLTGDAMSNEQKDDRRRHGGGPKSSWSDLREMGLLEVEAINYIRGRSIPHQFMVVDEAQNLTPHEVKTIVTR
VGEGTKIVFTGDPYQIDNPYVDAESNGLTWLAERLKGQALVGHMTLTRGERSALAELAANML
MNKKVVVLDTNVLLHDPEAPSSFGSDRIVLPIQVIEEIDRFKRDPSEKGRNSRRIARLLDSLRERGNLADGVPLTPNSDG
TLEVAFCRAETLAQLPPELRGGGGDNNILAVALEQMRAKGLSEAPEVVLITKDTNLRIKADAVGLAAQDYANDKVAISDL
YPGARGVKVSADLIDELHQNGRLSLKALPTETVASLQPNEGVTLIDRDSSDHTFLARQHGDSGELEPLVWLKRARLGRLK
PRNREQNFALDLLLDPSVELVTLVGKAGTGKTLLAIAAGLHQVADEHRYARLLVTRPPISLGKEIGFLPGTLDEKLAPWM
QPIVDNLDFLTGDAMSNEQKDDRRRHGGGPKSSWSDLREMGLLEVEAINYIRGRSIPHQFMVVDEAQNLTPHEVKTIVTR
VGEGTKIVFTGDPYQIDNPYVDAESNGLTWLAERLKGQALVGHMTLTRGERSALAELAANML
Download Length: 1389 bp
>T148585 NZ_CP063789:c35271-34753 [Tolypothrix sp. PCC 7712]
GTGACAGGCTCTCAAGAACAACAAATTCAGGCTCCAGAACCTCTCAATGCCGAGCATCAATTAGAAAACTTTGATTCCGG
TAATGCCGAACTGGATGAGTGGTTAAAAAAACGTGCTTTGAAAAACGAAGCTAGCGGAGCTTCCAGAACTTACGTGGTAA
CGGTGGGTCAGAAAGCGATCGCCTATTATTGTTTAGCAAATGGCAGTGTCATCAATACCACCGCTCCTGGTAAAGTCCGG
CGCAATATGCCAGACCCGATTCCCGTGATGGTCATTGGTCGGCTGGCGGTAGATATTAATTGGCAAGGGCAAGGTCTTGG
GTATGCTCTAGTGCGTGATGCAGTGCTTCGTACCCTCCAGGCAGCAAAGATTGCCGGAATCAGGGCGATTCTTGTTCATG
CCATTTCTGTTGAAGCGAAGCAGTTCTATGAGAAATGCGGTTTTATCCCCTCACCTGTTGCGCCGATGACCCTCATGGTA
ACGATCGCAGATGCGCTACAAGCGTTTGGAGTTGGGTAG
GTGACAGGCTCTCAAGAACAACAAATTCAGGCTCCAGAACCTCTCAATGCCGAGCATCAATTAGAAAACTTTGATTCCGG
TAATGCCGAACTGGATGAGTGGTTAAAAAAACGTGCTTTGAAAAACGAAGCTAGCGGAGCTTCCAGAACTTACGTGGTAA
CGGTGGGTCAGAAAGCGATCGCCTATTATTGTTTAGCAAATGGCAGTGTCATCAATACCACCGCTCCTGGTAAAGTCCGG
CGCAATATGCCAGACCCGATTCCCGTGATGGTCATTGGTCGGCTGGCGGTAGATATTAATTGGCAAGGGCAAGGTCTTGG
GTATGCTCTAGTGCGTGATGCAGTGCTTCGTACCCTCCAGGCAGCAAAGATTGCCGGAATCAGGGCGATTCTTGTTCATG
CCATTTCTGTTGAAGCGAAGCAGTTCTATGAGAAATGCGGTTTTATCCCCTCACCTGTTGCGCCGATGACCCTCATGGTA
ACGATCGCAGATGCGCTACAAGCGTTTGGAGTTGGGTAG
Antitoxin
Download Length: 297 a.a. Molecular weight: 32577.87 Da Isoelectric Point: 4.6048
>AT148585 WP_186519542.1 NZ_CP047961:1168520-1169410 [Synechococcus sp. PROS-9-1]
MTSNIMDPGLPSDDPARVAGNLEQIIHSDNYRLAHQDLDLLNSSSMRGVRMLLEISKPELYFAEAGITSTIIVFGGARLQ
EKSAAEASLKEAIRELDADPDSTAWKRKVSRARKMLELSSFYDAAREFAFLASHFGQSGSNSGPCCSSHVIVTGGGPGIM
EAANRGAFDAGCRSIGLNIELPNEQNPNPYITPDLCFKFNYFALRKFHFVMRAVGAVLFPGGYGTLDELFELLTLRQVGT
QHAMPIVLFGKDYWSRLVDFEFMADSGLIDDEDLQLIQFADTAAEAWDLIRECSSS
MTSNIMDPGLPSDDPARVAGNLEQIIHSDNYRLAHQDLDLLNSSSMRGVRMLLEISKPELYFAEAGITSTIIVFGGARLQ
EKSAAEASLKEAIRELDADPDSTAWKRKVSRARKMLELSSFYDAAREFAFLASHFGQSGSNSGPCCSSHVIVTGGGPGIM
EAANRGAFDAGCRSIGLNIELPNEQNPNPYITPDLCFKFNYFALRKFHFVMRAVGAVLFPGGYGTLDELFELLTLRQVGT
QHAMPIVLFGKDYWSRLVDFEFMADSGLIDDEDLQLIQFADTAAEAWDLIRECSSS
Download Length: 891 bp
>AT148585 NZ_CP063789:c35583-35275 [Tolypothrix sp. PCC 7712]
ATGCAGCCCCAAACAGGATCGTCCAACCATCAAAACCGTGATGTCACTATCAACATCAGGGCACACCAGGGACAACGGGA
TTTAATTGACCGAGCAGCAGAAGCCCTGGGCAAGAACCGTTCCGATTTCATGCTGGAGACCGCCTGTCGAGAAGCAGAAG
CAGTTTTGCTAGATCGGCGGCTGTTTATGCTGGATGATGAAAAGTTTCAGCAATTTGTCGAATTACTGGATCAGCCACCT
GCCACCAATGCCAACCTCCGGAAGTTGCTCACCAAGAAAGCACCTTGGGAACAGGGCGTGGGGGAGTAG
ATGCAGCCCCAAACAGGATCGTCCAACCATCAAAACCGTGATGTCACTATCAACATCAGGGCACACCAGGGACAACGGGA
TTTAATTGACCGAGCAGCAGAAGCCCTGGGCAAGAACCGTTCCGATTTCATGCTGGAGACCGCCTGTCGAGAAGCAGAAG
CAGTTTTGCTAGATCGGCGGCTGTTTATGCTGGATGATGAAAAGTTTCAGCAATTTGTCGAATTACTGGATCAGCCACCT
GCCACCAATGCCAACCTCCGGAAGTTGCTCACCAAGAAAGCACCTTGGGAACAGGGCGTGGGGGAGTAG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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