Detailed information of TA system TA148583

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PhoH-LOG/-
• Location: 1522746..1525057
• Replicon: chromosome
• Accession: NZ_CP047959
• Organism: Synechococcus sp. SYN20

Toxin (Protein)

• Gene name: PhoH
• Uniprot ID: -
• Locus tag: SynSYN20_RS07915
• Protein ID: WP_186522798.1
• Coordinates: 1522746..1524149 (+)
• Length: 468 a.a.

Antitoxin (Protein)

• Gene name: LOG
• Uniprot ID: -
• Locus tag: SynSYN20_RS07920
• Protein ID: WP_186525525.1
• Coordinates: 1524176..1525057 (+)
• Length: 294 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SynSYN20_RS07890	1517992..1518375	+	384	WP_186522793.1	hypothetical protein	-
SynSYN20_RS07895	1518665..1520197	-	1533	WP_186522794.1	acyl--CoA ligase	-
SynSYN20_RS07900	1520339..1521016	-	678	WP_186522795.1	phosphoesterase	-
SynSYN20_RS07905	1521095..1521319	+	225	WP_186525524.1	hypothetical protein	-
SynSYN20_RS07910	1521291..1522565	-	1275	WP_186522796.1	cytochrome P450	-
SynSYN20_RS07915	1522746..1524149	+	1404	WP_186522798.1	PhoH family protein	Toxin
SynSYN20_RS07920	1524176..1525057	+	882	WP_186525525.1	LOG family protein	Antitoxin
SynSYN20_RS07925	1525391..1526176	+	786	WP_186522800.1	ATP-binding cassette domain-containing protein	-
SynSYN20_RS07930	1526214..1526780	-	567	WP_186522802.1	hypothetical protein	-
SynSYN20_RS07935	1526833..1526976	-	144	WP_186522804.1	hypothetical protein	-
SynSYN20_RS07940	1527136..1527533	+	398	Protein_1551	hypothetical protein	-
SynSYN20_RS07945	1527736..1527969	-	234	WP_186522806.1	DUF3136 domain-containing protein	-
SynSYN20_RS07950	1528498..1529478	+	981	WP_186522808.1	phosphate ABC transporter substrate-binding protein PstS	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (11-155)

Antitoxin

• LOG family (155-284)

Sequences

Toxin

Protein

• Length: 468 a.a.
• Molecular weight: 51086.29 Da
• Isoelectric Point: 5.9030

>T148583 WP_186522798.1 NZ_CP047959:1522746-1524149 [Synechococcus sp. SYN20]
MNKKVVVKKVVVLDTNVLLHDPEAPSSFGSDRIVLPIQVIEEIDRFKRDPSEKGRNSRRVARLLDGLRERGNLADGVPLT
PDGDGTLEVAFCRAETLAQLPPELRGGGGDNNILAVALEQMRAKGLSEAPEVVLITKDTNLRIKADAVGLAAQDYANDKV
AISDLYPGARGVKVSADLIDELRQNGRLSLKALPAEAVASLQPNEGVTLIDRDSSDHTFLARQHGDSGELEPLVWLKRAR
LGRLKPRNREQNFALDLLLDPSVELVTLVGKAGTGKTLLAIAAGLHQVADEHRYARLLVTRPPISLGKEIGFLPGTLDEK
LAPWMQPIVDNLDFLTGDAMSNEQKDDRRRHGGGPKSSWSDLREMGLLEVEAINYIRGRSIPHQFMVVDEAQNLTPHEVK
TIVTRVGEGTKIVFTGDPYQIDNPYVDAESNGLTWLAERLKGQTLVGHMTLTRGERSALAELAANML

Nucleotide

• Length: 1404 bp

>T148583 NZ_CP063785:5304100-5304405 [Tolypothrix sp. PCC 7712]
GTGGGTATCTCCTCTATCACTGTGGCGGAACTTGAATATGGAGTAGCCAAGAGCCAACAGCAAGAGAAAAACCGCACCGC
CCTGCTACAATTTTTGCTACCCCTAGAAATAGTTGATTTCAATCCAACAGCAGCAACGATTTACGGCAGCATTAGAAGCG
ATCTCGAAACTAGAGGAATCATTATTGGTGCAATGGATATGCTCATTGCTGCTCATGCTCTAAGTTTAGGAGTTATTCTT
GTTACTAATAATCTAAGAGAATTTTCGCGCATTCCTGCGCTGTTATTAGAGAACTGGGTTGATTAG

Antitoxin

Protein

• Length: 294 a.a.
• Molecular weight: 32598.08 Da
• Isoelectric Point: 5.1988

>AT148583 WP_186525525.1 NZ_CP047959:1524176-1525057 [Synechococcus sp. SYN20]
MDSGLPSENPARVAHNLEQIIHSDNYRLAHQDLDLLNRSSMRGVRMLLEIRKPELFLEEAGITSTIIVFGGARLQEKLAA
EASLKEAIKELDANPDSAEWKRKVSRARKMVELSSYYDAAREFAFLASHFGQSGPISGPSCSTHVIVTGGGPGIMEAANR
GAFDAGCRSIGLNIELPHEQNPNPYITPNLCFKFNYFALRKFHFVMRAVGAVLFPGGYGTLDELFELLTLRQVGTQHAMP
IVLFGKDYWSRLIDFEFMADSGLIDDEDLKLIQFADTATEAWDLIQNQTFNPG

Nucleotide

• Length: 882 bp

>AT148583 NZ_CP063785:5303777-5304004 [Tolypothrix sp. PCC 7712]
ATGAACACCGCTAAACTTAGCACTGATGGCACTCACCAAGTTGTGATTTTGCCGGAAGATTTTCAACTCACTGGCACGGA
AGTTTATATTAAAAAAATTGGTAATGCCATTATTCTCATTGCCAAAGATAACTCCTGGCAATCTCTCATTGAGAGTTTGG
ACAATTTCTCCGATGATTTCATGACTACTAGAGAGCAGCCACTAATAGACACCAGAGAGAGTTTGTAA