Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PhoH-LOG/- |
| Location | 1216690..1219020 | Replicon | chromosome |
| Accession | NZ_CP047954 | ||
| Organism | Synechococcus sp. M16.1 | ||
Toxin (Protein)
| Gene name | PhoH | Uniprot ID | - |
| Locus tag | SynM161_RS07060 | Protein ID | WP_186540494.1 |
| Coordinates | 1217632..1219020 (-) | Length | 463 a.a. |
Antitoxin (Protein)
| Gene name | LOG | Uniprot ID | - |
| Locus tag | SynM161_RS07055 | Protein ID | WP_186542585.1 |
| Coordinates | 1216690..1217574 (-) | Length | 295 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SynM161_RS07010 | 1211765..1212475 | - | 711 | WP_186540484.1 | response regulator transcription factor | - |
| SynM161_RS07015 | 1212501..1212686 | - | 186 | WP_186540486.1 | hypothetical protein | - |
| SynM161_RS07020 | 1212884..1213111 | + | 228 | WP_186540488.1 | hypothetical protein | - |
| SynM161_RS07025 | 1213777..1213956 | + | 180 | WP_115009186.1 | hypothetical protein | - |
| SynM161_RS07030 | 1213991..1214182 | + | 192 | WP_115009187.1 | hypothetical protein | - |
| SynM161_RS07035 | 1214286..1214441 | + | 156 | WP_170951393.1 | hypothetical protein | - |
| SynM161_RS07040 | 1214618..1215574 | + | 957 | WP_186540490.1 | orange carotenoid-binding protein | - |
| SynM161_RS07045 | 1215495..1216307 | + | 813 | WP_186540492.1 | fatty acid desaturase | - |
| SynM161_RS07050 | 1216357..1216677 | + | 321 | WP_115161907.1 | hypothetical protein | - |
| SynM161_RS07055 | 1216690..1217574 | - | 885 | WP_186542585.1 | LOG family protein | Antitoxin |
| SynM161_RS07060 | 1217632..1219020 | - | 1389 | WP_186540494.1 | PhoH family protein | Toxin |
| SynM161_RS07065 | 1219988..1220299 | + | 312 | WP_186540496.1 | hypothetical protein | - |
| SynM161_RS07070 | 1221599..1221859 | + | 261 | WP_186540498.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 463 a.a. Molecular weight: 50904.91 Da Isoelectric Point: 5.5920
>T148581 WP_186540494.1 NZ_CP047954:c1219020-1217632 [Synechococcus sp. M16.1]
MKDKVVVLDTNVLLHDPEAPHRFGDLRVVIPMQVVEEIDRFKKDHSEKGRNARRISRLLDSYRARGSLADGVPIEGTNHG
MLQVIFCQAQALQDLPAELQGGGGDNNILAVALEQMRCSGLKQAPEVVLISKDINLRIKADAVGLQAEDYVNDNVSIDDL
YTGFRELSTDAETIKTLHDEEQLPLEAVADPEGQHLQANEGVVLVDQRNDSHTLLARHQGNSNTIKPLHWLQRAHLGRIK
ARNREQSFALDLLLDPSVALVTLVGKAGTGKTLLAIAAGLHQVADTHHYARLLVTRPPISLGKDIGYLPGTLEEKLGPWM
KPIIDNIDFITGSTPGEEADQTKKQRQREPRNAWADLQGMGLLEVEAINTIRGRSIPHQFLVVDEAQNLTPLEVKTIVTR
VGEGTKVVFTGDPYQIDNPYVDAESNGLTWLVEKLKGQPLVGHMTLTKGERSELAELAANIL
MKDKVVVLDTNVLLHDPEAPHRFGDLRVVIPMQVVEEIDRFKKDHSEKGRNARRISRLLDSYRARGSLADGVPIEGTNHG
MLQVIFCQAQALQDLPAELQGGGGDNNILAVALEQMRCSGLKQAPEVVLISKDINLRIKADAVGLQAEDYVNDNVSIDDL
YTGFRELSTDAETIKTLHDEEQLPLEAVADPEGQHLQANEGVVLVDQRNDSHTLLARHQGNSNTIKPLHWLQRAHLGRIK
ARNREQSFALDLLLDPSVALVTLVGKAGTGKTLLAIAAGLHQVADTHHYARLLVTRPPISLGKDIGYLPGTLEEKLGPWM
KPIIDNIDFITGSTPGEEADQTKKQRQREPRNAWADLQGMGLLEVEAINTIRGRSIPHQFLVVDEAQNLTPLEVKTIVTR
VGEGTKVVFTGDPYQIDNPYVDAESNGLTWLVEKLKGQPLVGHMTLTKGERSELAELAANIL
Download Length: 1389 bp
>T148581 NZ_CP063785:c3840749-3840456 [Tolypothrix sp. PCC 7712]
ATGATAGTATCATTTAAGAACAAAGCAACTGAAGACATTTTTGATGGTAATGACTCAAAGGAAGCCCGAAAACAGTGTCC
CATAAATTGTTGGGGAGTTGCACAGAGAAAATTAGATCAACTCAATGCAGCGTTCTCTTTGGATGATATGAAAGTTCCTC
CAGGTAATAGGTTAGAAGCTTTAAAAGGTGACCGCAAGGGTCAGCATAGCATTCGGATTAATGACCAATACCGGATTTGC
TTTACATGGATACCTGAAGGAGTATCAGAAGTTGAAATAGTAGACTACCATTAG
ATGATAGTATCATTTAAGAACAAAGCAACTGAAGACATTTTTGATGGTAATGACTCAAAGGAAGCCCGAAAACAGTGTCC
CATAAATTGTTGGGGAGTTGCACAGAGAAAATTAGATCAACTCAATGCAGCGTTCTCTTTGGATGATATGAAAGTTCCTC
CAGGTAATAGGTTAGAAGCTTTAAAAGGTGACCGCAAGGGTCAGCATAGCATTCGGATTAATGACCAATACCGGATTTGC
TTTACATGGATACCTGAAGGAGTATCAGAAGTTGAAATAGTAGACTACCATTAG
Antitoxin
Download Length: 295 a.a. Molecular weight: 32691.83 Da Isoelectric Point: 4.7627
>AT148581 WP_186542585.1 NZ_CP047954:c1217574-1216690 [Synechococcus sp. M16.1]
MTQFPNTSSPEQANLDAILTSPTYRIAHEDQELLNSNDMRGVRMLLEITKPDLHLETAGIESTIIVFGGARIVDNDTAAA
KLAQAEQRLSENPGSPLLKRQVVHAQQLVELSRFYDAAREFASLASRHGQCNREQPHDCSSHVIVTGGGPGIMEAANRGA
FEAGCRSIGLNITLPFEQHPNPYITPDLCFKFNYFSLRKFHFVMRSIGAILFPGGFGTLDELFELLTLRQVGTKGSMPIV
LFGTEFWRRLVDFDYLAETGLISDDDLDLIHFSDSAEEAWDFIRSRTGAEPESN
MTQFPNTSSPEQANLDAILTSPTYRIAHEDQELLNSNDMRGVRMLLEITKPDLHLETAGIESTIIVFGGARIVDNDTAAA
KLAQAEQRLSENPGSPLLKRQVVHAQQLVELSRFYDAAREFASLASRHGQCNREQPHDCSSHVIVTGGGPGIMEAANRGA
FEAGCRSIGLNITLPFEQHPNPYITPDLCFKFNYFSLRKFHFVMRSIGAILFPGGFGTLDELFELLTLRQVGTKGSMPIV
LFGTEFWRRLVDFDYLAETGLISDDDLDLIHFSDSAEEAWDFIRSRTGAEPESN
Download Length: 885 bp
>AT148581 NZ_CP063785:c3840442-3840128 [Tolypothrix sp. PCC 7712]
ATGAGAGTTCCAAAGCATAGATCCCCCTCACATCCTGGGGAAATATTATTGAAAGATTTCTTAGAAGAAATGGGAATATC
ACAACGAGAACTTGCAGATGCAATACATGTTCCTTATCAGCGAATTAACGAGATTGTAAATCAAAAGCGGGGTATTACAC
CTAGTACAGCATTACGATTAGCTAAATTTTTTGGGAATAGTTCAGAGTTTTGGTTAAACCTCCAACAAAATTGGGAACTC
TACCATGTTTTGTTAGCAGAAGAAGCAGAATTAAAAAATATTAAACAGTTCAAAAGTTCTGAAGCAACGGCTTGA
ATGAGAGTTCCAAAGCATAGATCCCCCTCACATCCTGGGGAAATATTATTGAAAGATTTCTTAGAAGAAATGGGAATATC
ACAACGAGAACTTGCAGATGCAATACATGTTCCTTATCAGCGAATTAACGAGATTGTAAATCAAAAGCGGGGTATTACAC
CTAGTACAGCATTACGATTAGCTAAATTTTTTGGGAATAGTTCAGAGTTTTGGTTAAACCTCCAACAAAATTGGGAACTC
TACCATGTTTTGTTAGCAGAAGAAGCAGAATTAAAAAATATTAAACAGTTCAAAAGTTCTGAAGCAACGGCTTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|