148579

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PhoH-LOG/-
Location 957268..959574 Replicon chromosome
Accession NZ_CP047951
Organism Synechococcus sp. PROS-U-1

Toxin (Protein)


Gene name PhoH Uniprot ID -
Locus tag SynPROSU1_RS05130 Protein ID WP_186572256.1
Coordinates 958186..959574 (-) Length 463 a.a.

Antitoxin (Protein)


Gene name LOG Uniprot ID -
Locus tag SynPROSU1_RS05125 Protein ID WP_186571804.1
Coordinates 957268..958182 (-) Length 305 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SynPROSU1_RS05095 953715..954671 + 957 WP_186571800.1 ornithine carbamoyltransferase -
SynPROSU1_RS05100 954677..954985 + 309 WP_186571801.1 hypothetical protein -
SynPROSU1_RS05105 954997..955221 + 225 WP_186571802.1 hypothetical protein -
SynPROSU1_RS05110 955288..955911 + 624 WP_186571803.1 transcriptional repressor LexA -
SynPROSU1_RS05120 956379..956594 + 216 WP_186572255.1 hypothetical protein -
SynPROSU1_RS05125 957268..958182 - 915 WP_186571804.1 LOG family protein Antitoxin
SynPROSU1_RS05130 958186..959574 - 1389 WP_186572256.1 PhoH family protein Toxin
SynPROSU1_RS05135 960031..960237 - 207 WP_186572441.1 hypothetical protein -
SynPROSU1_RS05140 960280..960453 - 174 WP_186571805.1 hypothetical protein -
SynPROSU1_RS05145 960552..960779 - 228 WP_115023604.1 DUF3136 domain-containing protein -
SynPROSU1_RS05150 960825..961217 - 393 WP_186571806.1 RidA family protein -
SynPROSU1_RS05155 961281..962030 - 750 WP_186571807.1 hydroxyacylglutathione hydrolase -
SynPROSU1_RS05160 962071..962724 + 654 WP_186571812.1 ATP phosphoribosyltransferase -
SynPROSU1_RS05165 962724..964502 + 1779 WP_186571814.1 ABC transporter ATP-binding protein/permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-150)

Antitoxin

LOG family

(162-292)


Sequences

Toxin        


Download         Length: 463 a.a.        Molecular weight: 50829.09 Da        Isoelectric Point: 5.5349

>T148579 WP_186572256.1 NZ_CP047951:c959574-958186 [Synechococcus sp. PROS-U-1]
MKEKIVVLDTNVLLHDPDAPKRFGDLRVVIPMQVIEEIDRFKKDHSERGRNARRVARLLDAYRRRGSLADGVAIEGNTNG
ILQVVFCQANALKDLPVELQGGGGDNNILAVALEQSQCSGLKDAPEVVLISKDINLRIKADAVGLQAEDYINDNVSIDNL
YTGFRELNADAETMKTLLDEDQLSIASLGTIEGEQLTPNEGVVMVDQQNNSHTLLTRLQGTSKTLKPLHWLKRSHLGRIK
ARNREQSFSLDLLLDPSIALVTLVGKAGTGKTMLALAAGLHQVADTHQYTRLLVTRPPISLGKDIGYLPGTLEEKLGPWM
KPIIDNIDFITGAAPGDKSDQTKRQKNREPRNAWADLQGMGLLEVEAINTIRGRSIPNQFLVVDEAQNLTPLEVKTIVTR
VGEGTKVVFTGDPYQIDNPYVDAECNGLTWLVDKLKDQPLVGHMTLTKGERSELAELAANIL

Download         Length: 1389 bp

>T148579 NZ_CP063780:4322550-4323122 [Pseudomonas sp. OST1909]
ATGGACATGGAAAAAATCAAAGGCCGTCTCGATTTTCTGCGCGAAGCGGAAAAACTCAAGGATGTGCTCAGAAGTGCCCA
CACGGCTTCGGGCCGCACTGAAAGCACGGCCGAACACAGTTGGCGCCTGTGTCTGATGGCGATGGTGTTCGCCGATCAAT
TGCCCGGCCTGGACCTGCTGAAAATCCTCAAGATGTGCGTTATCCATGATTTGGGCGAAGCCATCCACGGCGATATCCCG
GCGGTCAGCCAGGCGGCCTTTCCCAACAAGGGCGAACAGGAGCGACTCGACCTGCTGCTGTTGGCGCAGTCCCTGGACAG
CCCCCTGAAAGCCGAGATCCTGACGTTATGGGATGACTACGAGAACGCGCGCTCGCCGGAAGCAAAAGCCGTCAAGGCCA
TGGACAAGCTGGAGACCCTGCTGCAGCACACCCAAGGACTGAACCCGCCCGATTTCGATTACGCCTTCAACCTGGCCTAC
GGCAAAAAACACACAGATGCCGACCCTTTGTTCGAAGCGCTGCGGGCGTTGATCGATCGGGCGACAGAGCAAAGGCTCCA
CGCCGCAGAGTGA

Antitoxin


Download         Length: 305 a.a.        Molecular weight: 33935.53 Da        Isoelectric Point: 6.2783

>AT148579 WP_186571804.1 NZ_CP047951:c958182-957268 [Synechococcus sp. PROS-U-1]
MKTNPEYQHMAQVADQVNTQTSNLDAILKSPTYRIAHEDPTLLNSNAMRGVRMLLEITKPDLGLETAGIESTIIVFGGAR
IVDRETAAQRLKEAEKCLSKNPKSTALKRKVIHHQHLLELSRFYDSAQKFAFLASQHGQANSDQNNGCSSHVIVTGGGPG
IMEAANRGAFEAGCRSIGLNISLPFEQHPNPYITPELCFKFNYFSLRKFHFVMRSVGAILFPGGFGTLDELFELLTLRQV
GTKGSMPIVLFGQNFWTRLVDFEYLTETGLISDDDLELIHFSDTAEEAWEYIRSHTEAGQKIPE

Download         Length: 915 bp

>AT148579 NZ_CP063780:4321906-4322463 [Pseudomonas sp. OST1909]
ATGCCTCACTCGTTGCTCAAGCCTGCCTTGCCCGGCGTTGCGCTGCGGCGATGGCGTTTGCTGCACCGCATCAAGCAAAG
TCATGCAGCGCAGTTGTTCAACGTCACACAATCGACTATTTCGCGCTGGGAAAGTGGCGTACAAGCGATGGATCCGGCTG
CGCACCAACAGCTTGAGCAGTTGTTGGCAGCCCGACTTGATGCAGCCGCCGATCAGGCATTGGCCCGGCTGGTCAGCGAG
AGTTCGCAAGCGATGCACTTGGTGTGCGACCTGACGCACCGCCTGCTCGCGTGCTCGCCCTCCCGCGCACGCCAGTTCAG
CAGCCCGCTCGCCGAGCTTATGGGCCAGTCGTTGTGGCGCTTCGCAACGCCGCAAATCCAGCTGATCGAAGCCAGCCTGG
AGCATACCGGCTGGCGTGAAACCCAGGCACCACCGGCCCTTGAATTCACCACTGGAAGCAACGACTCCAATCTCGTGCCC
ATACGCCCAAGCCTGTGTCGCTGGACACGCATGACCCTGAGCGATGGCAGCGCAGCACGCCTGGTCGAGACACTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References