Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PhoH-LOG/-
Location 1290500..1292830 Replicon chromosome
Accession NZ_CP047950
Organism Synechococcus sp. A15-62

Toxin (Protein)


Gene name PhoH Uniprot ID -
Locus tag SynA1562_RS07425 Protein ID WP_186493347.1
Coordinates 1291442..1292830 (-) Length 463 a.a.

Antitoxin (Protein)


Gene name LOG Uniprot ID -
Locus tag SynA1562_RS07420 Protein ID WP_186493346.1
Coordinates 1290500..1291399 (-) Length 300 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SynA1562_RS07370 1285519..1285719 - 201 WP_186495352.1 hypothetical protein -
SynA1562_RS07375 1285922..1286794 - 873 WP_186493341.1 phycobilisome rod-core linker polypeptide -
SynA1562_RS07380 1286995..1287228 - 234 WP_186493342.1 hypothetical protein -
SynA1562_RS07385 1287332..1288042 - 711 WP_186495353.1 response regulator transcription factor -
SynA1562_RS07390 1288068..1288253 - 186 WP_186493343.1 hypothetical protein -
SynA1562_RS07395 1288666..1288893 + 228 WP_186493344.1 hypothetical protein -
SynA1562_RS07400 1289444..1289614 - 171 WP_186493345.1 hypothetical protein -
SynA1562_RS07405 1289812..1289991 + 180 WP_025362229.1 hypothetical protein -
SynA1562_RS07410 1290034..1290210 + 177 WP_006851728.1 hypothetical protein -
SynA1562_RS07415 1290314..1290481 + 168 WP_170951026.1 hypothetical protein -
SynA1562_RS07420 1290500..1291399 - 900 WP_186493346.1 LOG family protein Antitoxin
SynA1562_RS07425 1291442..1292830 - 1389 WP_186493347.1 PhoH family protein Toxin
SynA1562_RS07430 1293044..1293223 - 180 WP_186493348.1 hypothetical protein -
SynA1562_RS07435 1293755..1294066 + 312 WP_186495354.1 hypothetical protein -
SynA1562_RS07440 1294525..1294701 + 177 WP_186493349.1 hypothetical protein -
SynA1562_RS07445 1295378..1295638 + 261 WP_186493350.1 hypothetical protein -
SynA1562_RS07450 1295911..1296084 + 174 WP_186495450.1 hypothetical protein -
SynA1562_RS07455 1296099..1296287 - 189 WP_186493351.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-150)

Antitoxin

LOG family

(158-286)


Sequences

Toxin        


Download         Length: 463 a.a.        Molecular weight: 50921.91 Da        Isoelectric Point: 5.6950

>T148578 WP_186493347.1 NZ_CP047950:c1292830-1291442 [Synechococcus sp. A15-62]
MKDKIVVLDTNVLLHDPEAPHRFGDLRVVIPMQVVEEIDRFKKDHSEKGRNARRISRLLDSYRARGSLADGVPIEGTNHG
MLQVIFCQAQALQDLPAELQGGGGDNNILAVALEQMRCSGLKQAPEVVLISKDINLRIKADAVGLQAEDYVNDNVSIDDL
YAGFRELSTDAETIQTLHDEDQLPLEAVADREGQHLQANEAVVLVDQHNDSHTLLGRHQGNSNIIKPLHWLNRAHLGRIK
ARNREQSFALDLLLDPSVALVTLVGKAGTGKTLLAIAAGLHQVADTHHYARLLVTRPPISLGKDIGYLPGTLEEKLGPWM
KPIIDNIDFITGSSPGEEAEQTKKQRHREPRNAWADLQGMGLLEVEAINTIRGRSIPHQFLVVDEAQNLTPLEVKTIVTR
VGEGTKVVFTGDPYQIDNPYVDAESNGLTWLVEKLKGQPLVGHMTLTKGERSELAELAANIL

Download         Length: 1389 bp

>T148578 NZ_CP063780:c3963855-3963610 [Pseudomonas sp. OST1909]
ATCGGCGACCTGATTGATATCGTGACTTTTATCGCAGCAGAAAGCCCCGGCGCTGCACGACGCATCAAGACCCGCCTGGA
AGGCGCGCCTCTACCACTGGCTGAGCACCCCTGTCTATATCCGTGCGGCCGGGTGCCAGGTACTCGTGAGGTGGTTGTAC
ATCCCAATTATGTGCTGGTGTATAGAGTGACTGCCGAGCGGATCGAAATAGTCAACGTATTGCACGCCAGGCAAGAATAT
CCCTGA

Antitoxin


Download         Length: 300 a.a.        Molecular weight: 33173.53 Da        Isoelectric Point: 5.3275

>AT148578 WP_186493346.1 NZ_CP047950:c1291399-1290500 [Synechococcus sp. A15-62]
MTVEHMTQFPNTASPEQANLDAILHSPTYRIAHEDQDLLNSNDMRGVRMLLEITKPDLHLETAGIESTIIVFGGARIVDN
DTAAAKLAQAEQRLSETPGSPVLKRHVVHAQQLVELSRFYDAAREFASLASRHGQANKGEIHGCSSHVIVTGGGPGIMEA
ANRGAFEAGCRSIGLNITLPFEQHPNPYITPDLCFKFNYFSLRKFHFVMRSIGAILFPGGFGTLDELFELLTLRQVGTKG
NMPIVLFGTEFWRRLVDFDYLAEMGLISDDDLDLIHFSDSAQEAWDFIRSRTQADPQAS

Download         Length: 900 bp

>AT148578 NZ_CP063780:c3964080-3963886 [Pseudomonas sp. OST1909]
ATGGGTGTTCAACTTTCCCCAATTGTTTCCGAGTTTGAAACCGAAGAGCAGGCGAGTAGTCATGATCTCTGGTTTCGTAA
AAAAGTCGAAAAAAGCTTGGCCAACCCCGGCCTCGGTGTACCTCATGACGAGGTCATGGCACGAGTTGAGGCGATTATTC
TGCAAGCAGAGCTTGAGCAGCGGGCCAAGGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References