148577

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) PhoH-LOG/-
Location 1172053..1174383 Replicon chromosome
Accession NZ_CP047949
Organism Synechococcus sp. RS9902

Toxin (Protein)


Gene name PhoH Uniprot ID -
Locus tag SynRS9902_RS06265 Protein ID WP_186510389.1
Coordinates 1172053..1173441 (+) Length 463 a.a.

Antitoxin (Protein)


Gene name LOG Uniprot ID -
Locus tag SynRS9902_RS06270 Protein ID WP_186510390.1
Coordinates 1173484..1174383 (+) Length 300 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SynRS9902_RS06245 1168130..1168507 - 378 WP_186510387.1 hypothetical protein -
SynRS9902_RS06250 1169252..1169512 - 261 WP_186510388.1 hypothetical protein -
SynRS9902_RS06255 1170188..1170364 - 177 WP_186493349.1 hypothetical protein -
SynRS9902_RS06260 1170816..1171127 - 312 WP_186510554.1 hypothetical protein -
SynRS9902_RS06265 1172053..1173441 + 1389 WP_186510389.1 PhoH family protein Toxin
SynRS9902_RS06270 1173484..1174383 + 900 WP_186510390.1 LOG family protein Antitoxin
SynRS9902_RS06275 1174402..1174569 - 168 WP_170950626.1 hypothetical protein -
SynRS9902_RS06280 1174673..1174849 - 177 WP_006851728.1 hypothetical protein -
SynRS9902_RS06285 1174892..1175071 - 180 WP_115082421.1 hypothetical protein -
SynRS9902_RS06290 1175992..1176219 - 228 WP_115082420.1 hypothetical protein -
SynRS9902_RS06295 1176299..1177135 - 837 WP_186510391.1 DUF429 domain-containing protein -
SynRS9902_RS06300 1177336..1177755 + 420 WP_186510392.1 hypothetical protein -
SynRS9902_RS06305 1177737..1178435 + 699 WP_186510555.1 response regulator transcription factor -
SynRS9902_RS06310 1178557..1178790 + 234 WP_186510393.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(239-453)

Antitoxin

(158-286)


Sequences


Toxin        


Download         Length: 463 a.a.        Molecular weight: 50903.89 Da        Isoelectric Point: 5.8441

>T148577 WP_186510389.1 NZ_CP047949:1172053-1173441 [Synechococcus sp. RS9902]
MKDKIVVLDTNVLLHDPEAPHRFGDLRVVIPMQVVEEIDRFKKDHSEKGRNARRISRLLDSYRVRGSLADGVPIEGTNHG
MLQVVFCQAQALSALPAELQGGGGDNNILAVALEQMRCSGLTQAPEVVLISKDINLRIKADAVGLQAEDYVNDNVSIDDL
YAGFRELSTDAETIQTLHDEDQLPLEAVINSEEQHLQANEGVVLVDQRNDSHTLLGRHQGNSNSIKPLHWLHRAHLGRIK
ARNREQSFALDLLLDPSVALVTLVGKAGTGKTLLAIAAGLHQVADTHHYARLLVTRPPISLGKDIGYLPGTLEEKLGPWM
KPIIDNIDFITGSSPGENTEQTKKRRHREPRNAWADLQGMGLLEVEAINTIRGRSIPNQFLVVDEAQNLTPLEVKTIVTR
VGEATKVVFTGDPYQIDNPYVDAESNGLTWLVEKLKGQPLVGHMTLTKGERSELAELAANIL

Download         Length: 1389 bp

>T148577 NZ_CP063780:c2010055-2009741 [Pseudomonas sp. OST1909]
ATGATTTTCATAGAGACGTCAGTCTTCACCCGTCGCGTTAAAGAATTGATCGACGAGGATGCCTACACGGCTCTTCAGAA
CGTGTTGGTAGTCAACCCTTCTGCTGGCGATGTAATCGAGGGTACGGGTGGAGTTCGCAAGATACGAGTAGCGGCCAAGG
GCCATGGCAAACGTGGCGGGGCGCGGGTGATCTATTACCATTTCGTCTCGGCATCACAGATTGTTTTACTGATGATCTAT
CCCAAAAATGAACAGCAGGACTTGACTGCCGTAGAGCGCAAGTCACTGAAGGCTGCGATTGAGCACTGGAGATAG

Antitoxin


Download         Length: 300 a.a.        Molecular weight: 33278.77 Da        Isoelectric Point: 5.0448

>AT148577 WP_186510390.1 NZ_CP047949:1173484-1174383 [Synechococcus sp. RS9902]
MTVEHMFQLPSTASPEQANLDAILKSLTYRIAHEDPDLLNSNAMRGVRMLLEITKPDLHLETAGIESTIIVFGGARIVDK
DTAFAKLTQAEQRLSATPGSPVLKRQVVHAQQLVELSRFYDAAREFASLASRHGQCNREQPHDCSSHVIVTGGGPGIMEA
ANRGAFEEGCRSIGLNITLPFEQHPNPYITPDLCFKFNYFSLRKFHFVMRSIGAILFPGGFGTLDELFELLTLRQVGTKG
SMPIVLFGSEFWRRLVDFDYLAETGLISDDDLDLIHFSDSAEEAWDFICNRTQADPQAS

Download         Length: 900 bp

>AT148577 NZ_CP063780:c2009738-2009451 [Pseudomonas sp. OST1909]
ATGAGCAGATTTTTTGATGAACTGATGGAAAGCGTTCAAGAGATGAACGAGATCCTGCGCGGAGAACGCGAACCTTCTCG
TGAGTTCCATGTTGATTCAATGCGAGTCAAAGAGATCCGTAAGGCGACAGGGCTAACCCAGGCTAAATTCGCAGCGCTGA
TTGATGTGCAACTTGGCACGTTACGGAACTGGGAGCAGGGTCGTCGTGAGCCTACCGGACCAGCAAAGGCATTGTTGAAA
GCTATCCATAATGACCCAGTCCATGTACTGAATGCGTTGGCTAGCTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References