Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | PhoH-LOG/- |
Location | 1139245..1141548 | Replicon | chromosome |
Accession | NZ_CP047948 | ||
Organism | Synechococcus sp. A15-127 |
Toxin (Protein)
Gene name | PhoH | Uniprot ID | - |
Locus tag | SynA15127_RS05755 | Protein ID | WP_186485364.1 |
Coordinates | 1139245..1140633 (+) | Length | 463 a.a. |
Antitoxin (Protein)
Gene name | LOG | Uniprot ID | - |
Locus tag | SynA15127_RS05760 | Protein ID | WP_186485365.1 |
Coordinates | 1140664..1141548 (+) | Length | 295 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
SynA15127_RS05725 | 1135638..1135907 | + | 270 | WP_043690761.1 | hypothetical protein | - |
SynA15127_RS05730 | 1135950..1136354 | + | 405 | WP_186485360.1 | hypothetical protein | - |
SynA15127_RS05735 | 1136384..1136992 | + | 609 | WP_186485361.1 | hypothetical protein | - |
SynA15127_RS05740 | 1137011..1137442 | - | 432 | WP_186485362.1 | type II toxin-antitoxin system VapC family toxin | - |
SynA15127_RS05745 | 1137439..1137693 | - | 255 | WP_186485593.1 | Arc family DNA-binding protein | - |
SynA15127_RS05750 | 1137795..1138637 | - | 843 | WP_186485363.1 | DUF429 domain-containing protein | - |
SynA15127_RS05755 | 1139245..1140633 | + | 1389 | WP_186485364.1 | PhoH family protein | Toxin |
SynA15127_RS05760 | 1140664..1141548 | + | 885 | WP_186485365.1 | LOG family protein | Antitoxin |
SynA15127_RS05765 | 1141556..1141714 | - | 159 | WP_186485773.1 | hypothetical protein | - |
SynA15127_RS05770 | 1141776..1141952 | - | 177 | WP_186485366.1 | hypothetical protein | - |
SynA15127_RS05775 | 1142448..1142675 | - | 228 | WP_186485367.1 | hypothetical protein | - |
SynA15127_RS05780 | 1142920..1143750 | - | 831 | WP_186485368.1 | M20/M25/M40 family metallo-hydrolase | - |
SynA15127_RS05785 | 1144264..1144911 | + | 648 | WP_186485369.1 | ParA family protein | - |
SynA15127_RS05790 | 1144948..1145655 | + | 708 | WP_186485370.1 | response regulator transcription factor | - |
SynA15127_RS05795 | 1145903..1146130 | - | 228 | WP_186485371.1 | DUF3136 domain-containing protein | - |
SynA15127_RS05800 | 1146278..1146496 | + | 219 | WP_043690834.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 463 a.a. Molecular weight: 50758.78 Da Isoelectric Point: 5.7449
>T148575 WP_186485364.1 NZ_CP047948:1139245-1140633 [Synechococcus sp. A15-127]
MKNKIVVLDTNVLLHDPEAPHRFGDLRVVIPMQVVEEIDRFKKDHSEKGRNARRISRLLDSYRARGSLADGVPIQGSDQG
MLQVIFCQTQALNELPAELQGGGGDNNILAVALEQMRCSGLKQAPEVVLISKDINLRIKADAVGLQAEDYINDNVSIDDL
YTGFRELSVDAETIKTLHDEDQLSLPAVTAAEGQHLQANEGVVMVDQHNDSHSLLARHQGNSNTIKPLHWLNRAHLGRIK
ARNREQSFALDLLLDPSIALVTLVGKAGTGKTLLALAAGLHQVADTHQYARLLVTRPPISLGKDIGYLPGTLEEKLGPWM
KPIIDNIDFITGASPGEDADQTKKQRHREPRNAWADLQGMGLLEVEAINTIRGRSIPNQFLVVDEAQNLTPLEVKTIVTR
VGEGTKVVFTGDPYQIDNPYVDAESNGLTWLVEKLKGQPLVGHMTLTKGERSELAELAANIL
MKNKIVVLDTNVLLHDPEAPHRFGDLRVVIPMQVVEEIDRFKKDHSEKGRNARRISRLLDSYRARGSLADGVPIQGSDQG
MLQVIFCQTQALNELPAELQGGGGDNNILAVALEQMRCSGLKQAPEVVLISKDINLRIKADAVGLQAEDYINDNVSIDDL
YTGFRELSVDAETIKTLHDEDQLSLPAVTAAEGQHLQANEGVVMVDQHNDSHSLLARHQGNSNTIKPLHWLNRAHLGRIK
ARNREQSFALDLLLDPSIALVTLVGKAGTGKTLLALAAGLHQVADTHQYARLLVTRPPISLGKDIGYLPGTLEEKLGPWM
KPIIDNIDFITGASPGEDADQTKKQRHREPRNAWADLQGMGLLEVEAINTIRGRSIPNQFLVVDEAQNLTPLEVKTIVTR
VGEGTKVVFTGDPYQIDNPYVDAESNGLTWLVEKLKGQPLVGHMTLTKGERSELAELAANIL
Download Length: 1389 bp
>T148575 NZ_CP063780:c895358-895059 [Pseudomonas sp. OST1909]
ATGAATCACTTCAAGAAGTCAAAACCTTTTCAGGAGTGGCTTGACGCGTTACGCAGTGAACCTGCCCGGGCACGCATATT
GGCAAGGTTGAAAAACGCACAATCAGGCAATTTCGGGGACTGTGAAGCAGTAGGAAATGGCGTATCGGAAATGCGCATTC
ATTACGGGCCTGGATACCGAGTTTATTTCATACGTAGAGACGAGGTGATTTATCTGTTGTTGATAGGAGGCGACAAATCA
ACGCAGAAACGAGACATCCAACGAGCAAAGCAAATTGCAGAAAGATTTGAAAAGGAATAA
ATGAATCACTTCAAGAAGTCAAAACCTTTTCAGGAGTGGCTTGACGCGTTACGCAGTGAACCTGCCCGGGCACGCATATT
GGCAAGGTTGAAAAACGCACAATCAGGCAATTTCGGGGACTGTGAAGCAGTAGGAAATGGCGTATCGGAAATGCGCATTC
ATTACGGGCCTGGATACCGAGTTTATTTCATACGTAGAGACGAGGTGATTTATCTGTTGTTGATAGGAGGCGACAAATCA
ACGCAGAAACGAGACATCCAACGAGCAAAGCAAATTGCAGAAAGATTTGAAAAGGAATAA
Antitoxin
Download Length: 295 a.a. Molecular weight: 32639.88 Da Isoelectric Point: 4.9546
>AT148575 WP_186485365.1 NZ_CP047948:1140664-1141548 [Synechococcus sp. A15-127]
MPGFNDQSNGEQANLDAILKSSTYRIAHEDPDLLNNNAMRGVRMLLEITKPDLDLETAGVESTIIVFGGARIVDRETALK
GLEEAERCLSENPGSSTLKRQVAHAEHRVVLSRFYDSAREFARLASQHGQANHKQCHGCASHVIVTGGGPGIMEAANRGA
FEAGCRSIGLNITLPFEQHPNPYITPDLCFRFNYFSLRKFHFVMRSIAAILFPGGFGTLDELFELLTLRQVGTKGSMPIV
LFGTEFWTKLVNFDYLAEMGLISDDDLDLIHFSDTAEEAWNFIRSQTLAEPEES
MPGFNDQSNGEQANLDAILKSSTYRIAHEDPDLLNNNAMRGVRMLLEITKPDLDLETAGVESTIIVFGGARIVDRETALK
GLEEAERCLSENPGSSTLKRQVAHAEHRVVLSRFYDSAREFARLASQHGQANHKQCHGCASHVIVTGGGPGIMEAANRGA
FEAGCRSIGLNITLPFEQHPNPYITPDLCFRFNYFSLRKFHFVMRSIAAILFPGGFGTLDELFELLTLRQVGTKGSMPIV
LFGTEFWTKLVNFDYLAEMGLISDDDLDLIHFSDTAEEAWNFIRSQTLAEPEES
Download Length: 885 bp
>AT148575 NZ_CP063780:c895055-894768 [Pseudomonas sp. OST1909]
ATGACTGAATTTACCGACTTCGATGTAGCGGAACACCTCAAAACCCCCGGGGACATGGCCGAATATCTTGAAGCCTGTTT
CGAGGAGGATGCGGGTGATGGCTTGCTTATTCGTTCAGCTCTCAACGACATCGCCCGTGCCCAAGGCATGACCCAAGTAG
CCCGTGATGCCGGCCTTGGACGTGAAAGCTTGTACAAAGCCCTCTCCAGCACGGGCAATCCCGAGTTTGGGACTATCATG
AAAGTCATGAAAGCATTGGGCCTCAAGCTTCATGCCACAGCGATCTGA
ATGACTGAATTTACCGACTTCGATGTAGCGGAACACCTCAAAACCCCCGGGGACATGGCCGAATATCTTGAAGCCTGTTT
CGAGGAGGATGCGGGTGATGGCTTGCTTATTCGTTCAGCTCTCAACGACATCGCCCGTGCCCAAGGCATGACCCAAGTAG
CCCGTGATGCCGGCCTTGGACGTGAAAGCTTGTACAAAGCCCTCTCCAGCACGGGCAATCCCGAGTTTGGGACTATCATG
AAAGTCATGAAAGCATTGGGCCTCAAGCTTCATGCCACAGCGATCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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