Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PhoH-LOG/-
Location 1139245..1141548 Replicon chromosome
Accession NZ_CP047948
Organism Synechococcus sp. A15-127

Toxin (Protein)


Gene name PhoH Uniprot ID -
Locus tag SynA15127_RS05755 Protein ID WP_186485364.1
Coordinates 1139245..1140633 (+) Length 463 a.a.

Antitoxin (Protein)


Gene name LOG Uniprot ID -
Locus tag SynA15127_RS05760 Protein ID WP_186485365.1
Coordinates 1140664..1141548 (+) Length 295 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SynA15127_RS05725 1135638..1135907 + 270 WP_043690761.1 hypothetical protein -
SynA15127_RS05730 1135950..1136354 + 405 WP_186485360.1 hypothetical protein -
SynA15127_RS05735 1136384..1136992 + 609 WP_186485361.1 hypothetical protein -
SynA15127_RS05740 1137011..1137442 - 432 WP_186485362.1 type II toxin-antitoxin system VapC family toxin -
SynA15127_RS05745 1137439..1137693 - 255 WP_186485593.1 Arc family DNA-binding protein -
SynA15127_RS05750 1137795..1138637 - 843 WP_186485363.1 DUF429 domain-containing protein -
SynA15127_RS05755 1139245..1140633 + 1389 WP_186485364.1 PhoH family protein Toxin
SynA15127_RS05760 1140664..1141548 + 885 WP_186485365.1 LOG family protein Antitoxin
SynA15127_RS05765 1141556..1141714 - 159 WP_186485773.1 hypothetical protein -
SynA15127_RS05770 1141776..1141952 - 177 WP_186485366.1 hypothetical protein -
SynA15127_RS05775 1142448..1142675 - 228 WP_186485367.1 hypothetical protein -
SynA15127_RS05780 1142920..1143750 - 831 WP_186485368.1 M20/M25/M40 family metallo-hydrolase -
SynA15127_RS05785 1144264..1144911 + 648 WP_186485369.1 ParA family protein -
SynA15127_RS05790 1144948..1145655 + 708 WP_186485370.1 response regulator transcription factor -
SynA15127_RS05795 1145903..1146130 - 228 WP_186485371.1 DUF3136 domain-containing protein -
SynA15127_RS05800 1146278..1146496 + 219 WP_043690834.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-150)

Antitoxin

LOG family

(153-281)


Sequences

Toxin        


Download         Length: 463 a.a.        Molecular weight: 50758.78 Da        Isoelectric Point: 5.7449

>T148575 WP_186485364.1 NZ_CP047948:1139245-1140633 [Synechococcus sp. A15-127]
MKNKIVVLDTNVLLHDPEAPHRFGDLRVVIPMQVVEEIDRFKKDHSEKGRNARRISRLLDSYRARGSLADGVPIQGSDQG
MLQVIFCQTQALNELPAELQGGGGDNNILAVALEQMRCSGLKQAPEVVLISKDINLRIKADAVGLQAEDYINDNVSIDDL
YTGFRELSVDAETIKTLHDEDQLSLPAVTAAEGQHLQANEGVVMVDQHNDSHSLLARHQGNSNTIKPLHWLNRAHLGRIK
ARNREQSFALDLLLDPSIALVTLVGKAGTGKTLLALAAGLHQVADTHQYARLLVTRPPISLGKDIGYLPGTLEEKLGPWM
KPIIDNIDFITGASPGEDADQTKKQRHREPRNAWADLQGMGLLEVEAINTIRGRSIPNQFLVVDEAQNLTPLEVKTIVTR
VGEGTKVVFTGDPYQIDNPYVDAESNGLTWLVEKLKGQPLVGHMTLTKGERSELAELAANIL

Download         Length: 1389 bp

>T148575 NZ_CP063780:c895358-895059 [Pseudomonas sp. OST1909]
ATGAATCACTTCAAGAAGTCAAAACCTTTTCAGGAGTGGCTTGACGCGTTACGCAGTGAACCTGCCCGGGCACGCATATT
GGCAAGGTTGAAAAACGCACAATCAGGCAATTTCGGGGACTGTGAAGCAGTAGGAAATGGCGTATCGGAAATGCGCATTC
ATTACGGGCCTGGATACCGAGTTTATTTCATACGTAGAGACGAGGTGATTTATCTGTTGTTGATAGGAGGCGACAAATCA
ACGCAGAAACGAGACATCCAACGAGCAAAGCAAATTGCAGAAAGATTTGAAAAGGAATAA

Antitoxin


Download         Length: 295 a.a.        Molecular weight: 32639.88 Da        Isoelectric Point: 4.9546

>AT148575 WP_186485365.1 NZ_CP047948:1140664-1141548 [Synechococcus sp. A15-127]
MPGFNDQSNGEQANLDAILKSSTYRIAHEDPDLLNNNAMRGVRMLLEITKPDLDLETAGVESTIIVFGGARIVDRETALK
GLEEAERCLSENPGSSTLKRQVAHAEHRVVLSRFYDSAREFARLASQHGQANHKQCHGCASHVIVTGGGPGIMEAANRGA
FEAGCRSIGLNITLPFEQHPNPYITPDLCFRFNYFSLRKFHFVMRSIAAILFPGGFGTLDELFELLTLRQVGTKGSMPIV
LFGTEFWTKLVNFDYLAEMGLISDDDLDLIHFSDTAEEAWNFIRSQTLAEPEES

Download         Length: 885 bp

>AT148575 NZ_CP063780:c895055-894768 [Pseudomonas sp. OST1909]
ATGACTGAATTTACCGACTTCGATGTAGCGGAACACCTCAAAACCCCCGGGGACATGGCCGAATATCTTGAAGCCTGTTT
CGAGGAGGATGCGGGTGATGGCTTGCTTATTCGTTCAGCTCTCAACGACATCGCCCGTGCCCAAGGCATGACCCAAGTAG
CCCGTGATGCCGGCCTTGGACGTGAAAGCTTGTACAAAGCCCTCTCCAGCACGGGCAATCCCGAGTTTGGGACTATCATG
AAAGTCATGAAAGCATTGGGCCTCAAGCTTCATGCCACAGCGATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References