Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PhoH-LOG/-
Location 1491710..1494027 Replicon chromosome
Accession NZ_CP047946
Organism Synechococcus sp. ROS8604

Toxin (Protein)


Gene name PhoH Uniprot ID -
Locus tag SynROS8604_RS07820 Protein ID WP_186543548.1
Coordinates 1491710..1493119 (+) Length 470 a.a.

Antitoxin (Protein)


Gene name LOG Uniprot ID -
Locus tag SynROS8604_RS07825 Protein ID WP_186543549.1
Coordinates 1493134..1494027 (+) Length 298 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SynROS8604_RS07780 1487033..1487260 - 228 WP_186545887.1 hypothetical protein -
SynROS8604_RS07785 1487629..1487769 - 141 WP_186543540.1 hypothetical protein -
SynROS8604_RS07790 1487773..1487958 + 186 WP_186543541.1 hypothetical protein -
SynROS8604_RS07795 1488028..1488240 - 213 WP_186543542.1 hypothetical protein -
SynROS8604_RS07800 1488239..1488463 + 225 WP_186543543.1 hypothetical protein -
SynROS8604_RS07805 1490197..1490760 + 564 WP_186545888.1 HupE/UreJ family protein -
SynROS8604_RS07810 1491075..1491245 + 171 WP_186543545.1 hypothetical protein -
SynROS8604_RS07815 1491242..1491538 + 297 WP_186543546.1 hypothetical protein -
SynROS8604_RS07820 1491710..1493119 + 1410 WP_186543548.1 PhoH family protein Toxin
SynROS8604_RS07825 1493134..1494027 + 894 WP_186543549.1 LOG family protein Antitoxin
SynROS8604_RS07830 1494055..1494288 - 234 WP_186543550.1 DUF3136 domain-containing protein -
SynROS8604_RS07835 1494404..1495090 - 687 WP_186543551.1 response regulator transcription factor -
SynROS8604_RS07840 1495154..1495372 - 219 WP_186543552.1 hypothetical protein -
SynROS8604_RS07845 1495518..1495745 + 228 WP_186543553.1 DUF3136 domain-containing protein -
SynROS8604_RS07850 1495755..1495955 + 201 WP_186546080.1 hypothetical protein -
SynROS8604_RS07855 1496522..1496653 - 132 WP_186543555.1 DUF3721 domain-containing protein -
SynROS8604_RS07860 1496897..1497454 + 558 WP_186543556.1 efflux RND transporter periplasmic adaptor subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PhoH-like protein

(246-455)

Antitoxin

LOG family

(160-288)


Sequences

Toxin        


Download         Length: 470 a.a.        Molecular weight: 51403.78 Da        Isoelectric Point: 6.3024

>T148574 WP_186543548.1 NZ_CP047946:1491710-1493119 [Synechococcus sp. ROS8604]
MEGKRFVVNKKVVVLDTNVLLHDPEAPKSFGADRIVLPIQVIEEIDRFKRDPSEKGRNSRHIARLLDGLRERGNLADGVP
LTPDGEGTLEVAFCRAETLAQLPPELRGGGGDNNILAVALEQMRAKGLSEPPEVVLITKDTNLRIKADAVGLAAQDYSND
KVAISDLYPGSRGVKVSADVIDELHQKGRLSVKALPADVMASLQPNEGLTLIDRDSADHTFLARHRGNSGEVEPLVWLKR
ARLGRLKPRNREQNFALDLLLDPSVELVTLVGKAGTGKTLLAIAAGLHQVADQHLYARLLVTRPPISLGKEIGFLPGSLE
EKLAPWMQPIVDNLDFLTGDTMSNEPKDDRRRHGGGPKSSWADLREMGLLEVEAINYIRGRSIPHQFMVVDEAQNLTPHE
VKTIVTRVGEGTKIVFTGDPYQIDNPYVDAESNGLTWLAERLKGQTLVGHMTLTRGERSALAELAANML

Download         Length: 1410 bp

>T148574 NZ_CP063780:c895055-894768 [Pseudomonas sp. OST1909]
ATGACTGAATTTACCGACTTCGATGTAGCGGAACACCTCAAAACCCCCGGGGACATGGCCGAATATCTTGAAGCCTGTTT
CGAGGAGGATGCGGGTGATGGCTTGCTTATTCGTTCAGCTCTCAACGACATCGCCCGTGCCCAAGGCATGACCCAAGTAG
CCCGTGATGCCGGCCTTGGACGTGAAAGCTTGTACAAAGCCCTCTCCAGCACGGGCAATCCCGAGTTTGGGACTATCATG
AAAGTCATGAAAGCATTGGGCCTCAAGCTTCATGCCACAGCGATCTGA

Antitoxin


Download         Length: 298 a.a.        Molecular weight: 33226.81 Da        Isoelectric Point: 5.5684

>AT148574 WP_186543549.1 NZ_CP047946:1493134-1494027 [Synechococcus sp. ROS8604]
MKSDAIDSTWPSDDPTRVADNLQQIIHSDTYRLAHQDLALLNTSSMRGVRMLLEISKPELHFEEIGISSTIIVFGGARLK
ERSAAEAHLEKAIRELDTDPNSKQLQRKVSRAKKLLELSPFYDAAREFAFLASRFGQSDTSTRPCCSSHVIVTGGGPGIM
EAANRGAFDAGCRSIGLNIELPHEQNPNPFITPELCFKFNYFALRKFHFVMRAVGAVLFPGGYGTLDELFEVLTLRQVGT
QHAMPIILFGKDYWTRLIDFEFMADSGLIDDQDLGLIQFADTATEAWDLLRDHPLHP

Download         Length: 894 bp

>AT148574 NZ_CP063780:c895358-895059 [Pseudomonas sp. OST1909]
ATGAATCACTTCAAGAAGTCAAAACCTTTTCAGGAGTGGCTTGACGCGTTACGCAGTGAACCTGCCCGGGCACGCATATT
GGCAAGGTTGAAAAACGCACAATCAGGCAATTTCGGGGACTGTGAAGCAGTAGGAAATGGCGTATCGGAAATGCGCATTC
ATTACGGGCCTGGATACCGAGTTTATTTCATACGTAGAGACGAGGTGATTTATCTGTTGTTGATAGGAGGCGACAAATCA
ACGCAGAAACGAGACATCCAACGAGCAAAGCAAATTGCAGAAAGATTTGAAAAGGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References