Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PhoH-LOG/-
Location 1301837..1304148 Replicon chromosome
Accession NZ_CP047942
Organism Synechococcus sp. MVIR-18-1

Toxin (Protein)


Gene name PhoH Uniprot ID -
Locus tag SynMVIR181_RS06835 Protein ID WP_186522798.1
Coordinates 1301837..1303240 (+) Length 468 a.a.

Antitoxin (Protein)


Gene name LOG Uniprot ID -
Locus tag SynMVIR181_RS06840 Protein ID WP_186588715.1
Coordinates 1303252..1304148 (+) Length 299 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SynMVIR181_RS06810 1297470..1298015 - 546 WP_186588712.1 ureidoglycolate lyase -
SynMVIR181_RS06815 1298400..1298780 + 381 WP_186588713.1 hypothetical protein -
SynMVIR181_RS06820 1299198..1300025 - 828 Protein_1327 ATPase -
SynMVIR181_RS06825 1300186..1300410 + 225 WP_186525524.1 hypothetical protein -
SynMVIR181_RS06830 1300382..1301656 - 1275 WP_186588714.1 cytochrome P450 -
SynMVIR181_RS06835 1301837..1303240 + 1404 WP_186522798.1 PhoH family protein Toxin
SynMVIR181_RS06840 1303252..1304148 + 897 WP_186588715.1 LOG family protein Antitoxin
SynMVIR181_RS06845 1304482..1305267 + 786 WP_186588716.1 ATP-binding cassette domain-containing protein -
SynMVIR181_RS06850 1305305..1305871 - 567 WP_186588717.1 hypothetical protein -
SynMVIR181_RS06855 1305924..1306067 - 144 WP_186522804.1 hypothetical protein -
SynMVIR181_RS06860 1306187..1306624 + 438 Protein_1335 hypothetical protein -
SynMVIR181_RS06865 1306827..1307060 - 234 WP_186588718.1 DUF3136 domain-containing protein -
SynMVIR181_RS06870 1307590..1308570 + 981 WP_186522808.1 phosphate ABC transporter substrate-binding protein PstS -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(11-155)

Antitoxin

LOG family

(160-289)


Sequences

Toxin        


Download         Length: 468 a.a.        Molecular weight: 51086.29 Da        Isoelectric Point: 5.9030

>T148562 WP_186522798.1 NZ_CP047942:1301837-1303240 [Synechococcus sp. MVIR-18-1]
MNKKVVVKKVVVLDTNVLLHDPEAPSSFGSDRIVLPIQVIEEIDRFKRDPSEKGRNSRRVARLLDGLRERGNLADGVPLT
PDGDGTLEVAFCRAETLAQLPPELRGGGGDNNILAVALEQMRAKGLSEAPEVVLITKDTNLRIKADAVGLAAQDYANDKV
AISDLYPGARGVKVSADLIDELRQNGRLSLKALPAEAVASLQPNEGVTLIDRDSSDHTFLARQHGDSGELEPLVWLKRAR
LGRLKPRNREQNFALDLLLDPSVELVTLVGKAGTGKTLLAIAAGLHQVADEHRYARLLVTRPPISLGKEIGFLPGTLDEK
LAPWMQPIVDNLDFLTGDAMSNEQKDDRRRHGGGPKSSWSDLREMGLLEVEAINYIRGRSIPHQFMVVDEAQNLTPHEVK
TIVTRVGEGTKIVFTGDPYQIDNPYVDAESNGLTWLAERLKGQTLVGHMTLTRGERSALAELAANML

Download         Length: 1404 bp

>T148562 NZ_CP063774:3830547-3830699 [Escherichia coli O25b:H4-ST131]
ATGCCACAGCGAACGTTTTTAATGATGTTAATCGTCGTCTGTGTGACGATTCTGTGTTTTGTCTGGATGGTGAGGGATTC
GCTTTGCGGACTCCGGCTCCAGCAGGGAAACACAGTGCTTGTGGCAACGTTAGCCTACGAAGTTAAACGTTAA

Antitoxin


Download         Length: 299 a.a.        Molecular weight: 33046.60 Da        Isoelectric Point: 5.6083

>AT148562 WP_186588715.1 NZ_CP047942:1303252-1304148 [Synechococcus sp. MVIR-18-1]
MVSNFLDSGLPSEDPTRVAHNLEQIIHSDNYRLAHQDLDLLNRSSMRGVRMLLEISKPELFLEEAGITSTIIVFGGARLQ
EKTAAEASLKEAIKELDANPDSAEWKRKVSRARKMVKLSSYYDAAREFAFLASHFGQSGPISGPSCSTHVIVTGGGPGIM
EAANRGAFDAGCRSIGLNIELPHEQNPNPYITPNLCFKFNYFALRKFHFVMRAVGAVLFPGGYGTLDELFELLTLRQVGT
QHAMPIVLFGKDYWSRLIDFEFMADSGLIDDKDLKLIQFADTATEAWDLIQNQTSNPG

Download         Length: 897 bp

>AT148562 NZ_CP063774:c3830495-3830435 [Escherichia coli O25b:H4-ST131]
GAGGCATTACAGTAGAGCCCTTGGTTGATTGATAAAAAAATCTCCAGGGGCTTTCTGCTGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References