148548

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PhoH-LOG/-
Location 1491008..1493338 Replicon chromosome
Accession NZ_CP047938
Organism Synechococcus sp. A15-44

Toxin (Protein)


Gene name PhoH Uniprot ID -
Locus tag SynA1544_RS08410 Protein ID WP_186512960.1
Coordinates 1491950..1493338 (-) Length 463 a.a.

Antitoxin (Protein)


Gene name LOG Uniprot ID -
Locus tag SynA1544_RS08405 Protein ID WP_186512959.1
Coordinates 1491008..1491907 (-) Length 300 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SynA1544_RS08365 1487250..1487477 + 228 WP_186512950.1 hypothetical protein -
SynA1544_RS08370 1487775..1487945 - 171 WP_186512951.1 hypothetical protein -
SynA1544_RS08375 1488143..1488322 + 180 WP_186512952.1 hypothetical protein -
SynA1544_RS08380 1488325..1488516 + 192 WP_186512954.1 hypothetical protein -
SynA1544_RS08385 1488617..1488772 + 156 WP_186512955.1 hypothetical protein -
SynA1544_RS08390 1488949..1489905 + 957 WP_186512956.1 orange carotenoid-binding protein -
SynA1544_RS08395 1489895..1490638 + 744 WP_186512957.1 fatty acid desaturase -
SynA1544_RS08400 1490687..1491007 + 321 WP_186512958.1 hypothetical protein -
SynA1544_RS08405 1491008..1491907 - 900 WP_186512959.1 LOG family protein Antitoxin
SynA1544_RS08410 1491950..1493338 - 1389 WP_186512960.1 PhoH family protein Toxin
SynA1544_RS08415 1494266..1494577 + 312 WP_186512961.1 hypothetical protein -
SynA1544_RS08420 1495038..1495214 + 177 WP_186512962.1 hypothetical protein -
SynA1544_RS08425 1495874..1496134 + 261 WP_186512963.1 hypothetical protein -
SynA1544_RS08430 1496789..1497253 + 465 WP_186512965.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-150)

Antitoxin

LOG family

(158-286)


Sequences

Toxin        


Download         Length: 463 a.a.        Molecular weight: 50773.67 Da        Isoelectric Point: 5.5739

>T148548 WP_186512960.1 NZ_CP047938:c1493338-1491950 [Synechococcus sp. A15-44]
MKDKIVVLDTNVLLHDPEAPHRFGDFRVVIPMQVVEEIDRFKKDHSEKGRNARRISRLLDSCRARGSLADGVPIEGTNHG
MLQVVFCQAQALQDLPAELQGGGGDNNILAVALEQMRCSGLKQAPEVVLISKDINLRIKADAVGLHAEDYVNDNVSIDDL
YAGFRELSTDAETIQTLHDEDQLPVEAVADPEGQHLQANEGVVLVDQRNDSHTLLARHQGNSNTIKPLHWLNRAHLGRIK
ARNREQSFALDLLLDPSVALVTLVGKAGTGKTLLAIAAGLHQVADTHHYARLLVTRPPISLGKDIGYLPGTLEEKLGPWM
KPIIDNIDFITGSSPGEDADQSKKQRQREPRNAWADLQGMGLLEVEAINTIRGRSIPHQFLVVDEAQNLTPLEVKTIVTR
VGEGTKVVFTGDPYQIDNPYVDAESNGLTWLVEKLKGQPLVGHMTLTKGERSELAELAANIL

Download         Length: 1389 bp

>T148548 NZ_CP063774:c1711358-1710951 [Escherichia coli O25b:H4-ST131]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATTCCCTGGCCGCTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGCATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCGCCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGACAGCGGAAAACGGCA
ACATTTATGGCTGGCAGCTGACAGCATGGACGAAGCCGAATGGCGGGATTTACGGCGGATATTGTTGCAACAAGAGACGC
AAAGATAA

Antitoxin


Download         Length: 300 a.a.        Molecular weight: 33172.57 Da        Isoelectric Point: 4.7479

>AT148548 WP_186512959.1 NZ_CP047938:c1491907-1491008 [Synechococcus sp. A15-44]
MTVEQMTQFPNTASPEQANLDAILNSPTYRIAHEDSDLLNSNDMRGVRMLLEITKPDLHLETAGIESTIIVFGGARIVDQ
VTAAAKLAQAEQLLSATPGSSALQRQVVHAKQLVELSRFYDAAREFACLASRHGQCNREQPHDCSSHVIVTGGGPGIMEA
ANRGAFDAGCRSIGLNITLPFEQHPNPYITPDLCFKFNYFSLRKFHFVMRSIGAILFPGGFGTLDELFELLTLRQVGTKG
SMPIVLFGTEFWRRLVDFDYLAEMSLISDDDLDLIHFSDTAEEAWEFIRSRTQAEPEAS

Download         Length: 900 bp

>AT148548 NZ_CP063774:c1711605-1711339 [Escherichia coli O25b:H4-ST131]
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCACCTTTATTCGTCTGCTGGAATGTGACGATCCGGACC
TGTTTAACTGGCTGATGAATCACGGTAAACCAGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References