Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PhoH-LOG/-
Location 907472..909802 Replicon chromosome
Accession NZ_CP047937
Organism Synechococcus sp. TAK9802

Toxin (Protein)


Gene name PhoH Uniprot ID -
Locus tag SynTAK9802_RS05160 Protein ID WP_186497622.1
Coordinates 907472..908860 (+) Length 463 a.a.

Antitoxin (Protein)


Gene name LOG Uniprot ID -
Locus tag SynTAK9802_RS05165 Protein ID WP_186497624.1
Coordinates 908903..909802 (+) Length 300 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SynTAK9802_RS05135 904669..904857 + 189 WP_186497614.1 hypothetical protein -
SynTAK9802_RS05140 905318..905578 - 261 WP_186497616.1 hypothetical protein -
SynTAK9802_RS05145 905979..906215 + 237 WP_186497618.1 hypothetical protein -
SynTAK9802_RS05150 906232..906543 - 312 WP_186498039.1 hypothetical protein -
SynTAK9802_RS05155 907078..907257 + 180 WP_186497620.1 hypothetical protein -
SynTAK9802_RS05160 907472..908860 + 1389 WP_186497622.1 PhoH family protein Toxin
SynTAK9802_RS05165 908903..909802 + 900 WP_186497624.1 LOG family protein Antitoxin
SynTAK9802_RS05170 909821..909988 - 168 WP_170951026.1 hypothetical protein -
SynTAK9802_RS05175 910092..910268 - 177 WP_186497626.1 hypothetical protein -
SynTAK9802_RS05180 910318..910497 - 180 WP_114989333.1 hypothetical protein -
SynTAK9802_RS05185 911163..911390 - 228 WP_186497629.1 hypothetical protein -
SynTAK9802_RS05190 911588..911773 + 186 WP_186497631.1 hypothetical protein -
SynTAK9802_RS05195 911976..912209 + 234 WP_186498040.1 hypothetical protein -
SynTAK9802_RS05200 912385..913254 + 870 WP_186497633.1 phycobilisome rod-core linker polypeptide -
SynTAK9802_RS05205 913698..914306 + 609 WP_186497635.1 hypothetical protein -
SynTAK9802_RS05210 914319..914543 + 225 WP_011364493.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PhoH-like protein

(239-453)

Antitoxin

LOG family

(158-286)


Sequences

Toxin        


Download         Length: 463 a.a.        Molecular weight: 50798.79 Da        Isoelectric Point: 5.7494

>T148545 WP_186497622.1 NZ_CP047937:907472-908860 [Synechococcus sp. TAK9802]
MKDKIVVLDTNVLLHDPEAPHRFGDLRVVIPMQVVEEIDRFKKDHSEKGRNARRISRLLDSYRARGSLADGVPIEGTNHG
MLQVIFCQAQALNALPAELQGGGGDNNILAVALEQMRCSGLTQAPEVVLISKDINLRIKADAVGLQAEDYVNDNVSIDDL
YAGFRELSTDAETIKTLHDEDQLPLEAVINSEEQHLQANEGVVLVDKRNDSHSLLARHQGNSNTIKPLHWLNRAHLGRIK
ARNREQNFALDLLLDPSVALVTLVGKAGTGKTLLAIAAGLHQVADTHHYARLLVTRPPISLGKDIGYLPGTLEEKLGPWM
KPIIDNIDFITGSSPGGDAEQTKKQRQREPRNSWADLQGMGLLEVEAINTIRGRSIPNQFLVVDEAQNLTPLEVKTIVTR
VGEGTKVVFTGDPYQIDNPYVDAESNGLTWLVEKLKGQPLVGHMTLTKGERSELAELAANIL

Download         Length: 1389 bp

>T148545 NZ_CP063774:777157-777531 [Escherichia coli O25b:H4-ST131]
ATGAAAACATTACCTGTATTACCCGGGCAGGCGGCCAGTTCTCGCCCGTCTCCTGTTGAAATCTGGCAGATACTGCTGTC
CCGACTGCTGGACCAGCACTATGGCCTCACACTGAATGACACACCGTTTGCCGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCGCCTGTACCCGCTCTCAGTTAATAAACAGCATCGATATCCTCCGGGCTCGCAGGGCGACCGGCCTGATGACCAGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAGTATCCGGAGGCGAAATGA

Antitoxin


Download         Length: 300 a.a.        Molecular weight: 33215.61 Da        Isoelectric Point: 5.0664

>AT148545 WP_186497624.1 NZ_CP047937:908903-909802 [Synechococcus sp. TAK9802]
MTVEHMTQFPSTASPEQANLDAILKSPTYRIAHEDPDLLNSNAMRGVRMLLEITKPDLHLETAGIESTIIVFGGARIVES
DTAAAKLAQAEQRLSETPSSPVLKRQVAHAQQLVELSRFYDAAREFASLASRHGQCNREQPHDCSSHVIVTGGGPGIMEA
ANRGAFEAGCRSIGLNITLPFEQHPNPYITPDLCFKFNYFSLRKFHFVMRSIGAILFPGGFGTLDELFELLTLRQVGTKG
SMPIVLFGTDFWKRLVDFDYLAETGLISDEDLDLIHFSDSADEAWEFIRSRTQAEPEAR

Download         Length: 900 bp

>AT148545 NZ_CP063774:776700-777068 [Escherichia coli O25b:H4-ST131]
GTGTCAGACAAACTCCATGAGACAAATTATCCCGACGACCATAACGACCGCCTCTGGTGGGGACTGCCCTGCACCGTGAC
GCCCTGTTTCGGGGCACGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGCCTGT
TCAGCGATGCAGATGCGTACCACCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCAAAAGGGCTGACCTGCAAAGCCGATACCCTCAGCAGTTG
TGGTTACGTTTATCTGGCTGTTTATCCGACGCCCGAAATGAAAAATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References