Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 1155157..1155664 Replicon chromosome
Accession NZ_CP047932
Organism Synechococcus sp. WH 8101

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag SynRCC2555_RS06000 Protein ID WP_130128976.1
Coordinates 1155157..1155420 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag SynRCC2555_RS06005 Protein ID WP_130128977.1
Coordinates 1155407..1155664 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SynRCC2555_RS05965 1150542..1150739 - 198 WP_130128971.1 hypothetical protein -
SynRCC2555_RS05970 1150901..1151641 - 741 WP_130130380.1 type 1 glutamine amidotransferase -
SynRCC2555_RS05975 1151882..1152292 - 411 WP_130128972.1 hypothetical protein -
SynRCC2555_RS05980 1152843..1153328 + 486 WP_165380936.1 hypothetical protein -
SynRCC2555_RS05985 1153424..1154077 + 654 WP_130128973.1 siphovirus Gp157 family protein -
SynRCC2555_RS05990 1154070..1154267 - 198 WP_130128974.1 hypothetical protein -
SynRCC2555_RS05995 1154266..1155102 + 837 WP_130128975.1 RAD52 family DNA repair protein -
SynRCC2555_RS06000 1155157..1155420 + 264 WP_130128976.1 BrnT family toxin Toxin
SynRCC2555_RS06005 1155407..1155664 + 258 WP_130128977.1 CopG family transcriptional regulator Antitoxin
SynRCC2555_RS06010 1155761..1156000 + 240 WP_130128978.1 DUF433 domain-containing protein -
SynRCC2555_RS06015 1156000..1156320 + 321 WP_130128979.1 hypothetical protein -
SynRCC2555_RS06020 1156419..1156709 - 291 WP_130130382.1 hypothetical protein -
SynRCC2555_RS06025 1157373..1158563 + 1191 WP_130128980.1 agmatinase -
SynRCC2555_RS06030 1158567..1158947 + 381 WP_130128981.1 hydrogenase maturation nickel metallochaperone HypA -
SynRCC2555_RS06035 1158950..1159654 + 705 WP_130128982.1 hydrogenase nickel incorporation protein HypB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1138438..1164101 25663


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-80)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10125.56 Da        Isoelectric Point: 8.7288

>T148543 WP_130128976.1 NZ_CP047932:1155157-1155420 [Synechococcus sp. WH 8101]
MDFEFDPRKSQANLEKHGIDFIAAQALWGDPALLEIPARPADEPRWLVIGRIQSKHWSAVITRRGQATRLISVRRSRPEE
IQLYEQF

Download         Length: 264 bp

>T148543 NZ_CP063774:c235685-234363 [Escherichia coli O25b:H4-ST131]
ATGCCTAAACTAGTCACTTGGATGAACAACCAGCGGGTAGGCGAGTTAACGAAGTTAGCCAACGGCGCGCACACCTTTAA
GTATGCAGCTGAGTGGTTAGCCAGCCGTTATGCCAGACCGTTGTCACTTTCGCTGCCATTGCAGAGGGGGAATATCACCT
CTGATGCCGTATTTAACTTCTTCGATAACCTGTTACCCGATAGCCCGATTGTACGTGACCGGATCGTTAAACGTTATCAT
GCTAAATCCAGACAACCGTTTGATTTATTGTCAGAAATAGGGCGAGACAGCGTTGGTGCCGTGACGTTAATCCCCGAAGA
TGAAACCGTAACGTGTCCGATAATGGCATGGGAAAAGCTTACTGAAGCCAGACTTGAAGAAGTATTAACGGCTTATAAAG
CAGATATCCCGTTAGGCATGATTAGAGAAGAAAATGACTTTCGCATCTCGGTTGCTGGCGCACAGGAGAAGACTGCGCTG
CTCAGAATAGGCAATGACTGGTGCATTCCGAAGGGAATAACGCCAACGACGCACATTATCAAATTGCCGATTGGCGAAAT
CAGACAGCCCAATGCGACGCTCGATCTTAGCCAAAGCGTTGATAATGAGTATTACTGTTTGCTGCTGGCGAAAGAACTCG
GGTTGAATGTTCCGGACGCAGAAATCATTAAAGCGGGAAGGGTGCGCGCGTTAGCGGTCGAACGTTTTGACAGGCGTTGG
AATACTGAGCGAACGGTTTTACTTCGCTTGCCACAGGAGGATATGTGCCAGACATTCGGTTTACCTTCATCGGTGAAATA
TGAATCAGATGGAGGCCCCGGTATCGCGCAAATTATGGCTTTTTTGATGGGGTCCAGCGAGGCGCTGAAAGATCGCTATG
ATTTTATGAAGTTTCAGGTCTTCCAGTGGTTGATTGGCGCAACGGATGGCCATGCAAAAAACTTCTCCGTATTTATTCAG
GCTGGCGGCAGTTATCGGCTCACACCATTTTACGACATCATTTCGGCATTTCCGGTCCTTGGCGGTACGGGAATACACAT
CAGCGATCTCAAACTGGCAATGGGGCTTAACGCATCCAAAGGCAAAAAAACGGCAATCGATAAAATTTATCCGCGACATT
TTCTGGCGACAGCAAAGGTGCTGAAATTCCCGGAAGTGCAGATGCATGAAATCCTGAGTGACTTTGCCAGAATGATTCCG
GCAGCACTGGATAACGTGAAGACTTCATTACCGACAGATTTTCCGGAGAACGTGGTGACGGCAGTTGAAACCAATGTGTT
GAGGTTGCACGATCGGTTAAGCCGAGAATACGGTATTAAGTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9926.10 Da        Isoelectric Point: 5.8703

>AT148543 WP_130128977.1 NZ_CP047932:1155407-1155664 [Synechococcus sp. WH 8101]
MNSSEFDRRFDSGESVLEGLDLESARRPRLEQKRVNVDFPLWMVDQLDREASRLGVTRQSIIKVWLSERLEHQRGVDPTQ
VSGNR

Download         Length: 258 bp

>AT148543 NZ_CP063774:c235951-235685 [Escherichia coli O25b:H4-ST131]
ATGATGAGCTTTCAGAAGATCTATAGCCCAACGCAATTGGCGAATGCAATGAAACTGGTTCGCCAGCAAAACGGCTGGAC
GCAGAGCGAGTTGGCGAAAAAAATCGGCATTAAGCAGGCGACAATTTCCAATTTCGAAAACAATCCTGACAATACCTCGC
TCACGACATTTTTTAAGATTTTACAGTCGCTTGAACTCTCAATGACGCTATGCGACGCGAAAAATGCCTCGCCAGAAGCA
ACAGAACAGCAAGATCTGGAGTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References