Detailed information of TA system TA148542

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-StbC
• Location: 1010987..1011684
• Replicon: chromosome
• Accession: NZ_CP047932
• Organism: Synechococcus sp. WH 8101

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: SynRCC2555_RS05120
• Protein ID: WP_130130358.1
• Coordinates: 1010987..1011409 (-)
• Length: 141 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: SynRCC2555_RS05125
• Protein ID: WP_130128843.1
• Coordinates: 1011427..1011684 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SynRCC2555_RS05115	1008078..1010990	-	2913	WP_130128842.1	DUF1156 domain-containing protein	-
SynRCC2555_RS05120	1010987..1011409	-	423	WP_130130358.1	type II toxin-antitoxin system VapC family toxin	Toxin
SynRCC2555_RS05125	1011427..1011684	-	258	WP_130128843.1	plasmid stabilization protein	Antitoxin
SynRCC2555_RS05130	1011791..1012024	+	234	WP_130128844.1	addiction module protein	-
SynRCC2555_RS05135	1012005..1012307	+	303	WP_130128845.1	type II toxin-antitoxin system RelE/ParE family toxin	-
SynRCC2555_RS05140	1012319..1015846	-	3528	WP_130128846.1	DUF3883 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (2-124)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 141 a.a.
• Molecular weight: 15211.32 Da
• Isoelectric Point: 5.5743

>T148542 WP_130130358.1 NZ_CP047932:c1011409-1010987 [Synechococcus sp. WH 8101]
VIVLDTNVISELMRPQPDQRVLAWANSLDPESAAITAMNEAEILHGLARLPGGRRKQALRESWDALAADLFAGRVWAFTS
EAAHWYGELVSHRERLARPIATADAVIAAIGLAHGAPLATRNTSDFADLGLQLINPWTIP

Nucleotide

• Length: 423 bp

>T148542 NZ_CP063773:4737161-4737505 [Pectobacterium carotovorum subsp. carotovorum PCCS1]
ATGAAGTCACTCTACTGGGTTGGCAGTAGCAAAAAGGATCTCCAGTCGCTACCTGCTGATGTGCAGGATGTGTTCGGTTA
CGCACTTCATATGGCTCAGACTGGTGGTAAGCACACTCAAGCCAAGCCACTTAAAGGTTTTGGTGGTGCAGGCGTATTAG
AAGTCGTTGAGGATTATATCGGCGATACTTATCGCGCAGTCTACACCGTCAAATTTGGAGAGGCAGTATACGTTCTACAT
GCTTTTCAGAAAAAATCGTCATCTGGCATTGCGACACCGAAACCCGATATGAACACCATCCGTGAACGCCTGAAAACCGC
AGAAAACCATGCAAAAGGAGCATAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9480.67 Da
• Isoelectric Point: 6.2304

>AT148542 WP_130128843.1 NZ_CP047932:c1011684-1011427 [Synechococcus sp. WH 8101]
MATLTIRNLDERTKAQLRVQAARHGRSMEEEARTILRTAIESSQAEVQVERLGSRIHAHFAELGGVELDLLERSSAPAAA
EFEPR

Nucleotide

• Length: 258 bp

>AT148542 NZ_CP063773:4737507-4737824 [Pectobacterium carotovorum subsp. carotovorum PCCS1]
ATGAGCCAGGATATTGAAGTCAGCAGCGGTAATGTGTACGCCGACCTTGGCAACTTGCATGCTGAAGATATGTTGGTCAA
AGCGCAGCTTGCCACCCTGATTAACTCAATCATCAAAAGCCGCCGTCTCACACAAGCAGAAGCAGCGAAGCTATTGGGCA
TGCCCCAACCCAAACTATCCAACTTATTACGTGGTCAGTTCAGGGGAATCAGTGAAACCAAAATGTTGGAATGCCTCACG
AAGCTGGGACGCGATATACAGATCGTTGTAGGGAAACCGCGCCGCACACCGGGCAGTGTTAAAGTCGTGTTTGCGTAG