Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 319579..320282 Replicon chromosome
Accession NZ_CP047932
Organism Synechococcus sp. WH 8101

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag SynRCC2555_RS01430 Protein ID WP_130128276.1
Coordinates 319579..320019 (-) Length 147 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag SynRCC2555_RS01435 Protein ID WP_130128277.1
Coordinates 320016..320282 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SynRCC2555_RS01405 315540..316757 - 1218 WP_130130288.1 DegT/DnrJ/EryC1/StrS family aminotransferase -
SynRCC2555_RS01410 316830..317381 + 552 WP_165380897.1 hypothetical protein -
SynRCC2555_RS01415 317362..317805 - 444 WP_130128273.1 hypothetical protein -
SynRCC2555_RS01420 317805..318683 - 879 WP_130128274.1 deoxyribodipyrimidine photo-lyase -
SynRCC2555_RS01425 318760..319542 + 783 WP_130128275.1 enoyl-ACP reductase FabI -
SynRCC2555_RS01430 319579..320019 - 441 WP_130128276.1 PIN domain-containing protein Toxin
SynRCC2555_RS01435 320016..320282 - 267 WP_130128277.1 DUF2191 domain-containing protein Antitoxin
SynRCC2555_RS01440 320408..321013 + 606 WP_130130290.1 imidazoleglycerol-phosphate dehydratase HisB -
SynRCC2555_RS01445 321090..322622 + 1533 WP_130128278.1 carotenoid oxygenase family protein -
SynRCC2555_RS01450 322576..323487 - 912 WP_130128279.1 hypothetical protein -
SynRCC2555_RS01455 323627..324355 + 729 WP_165380898.1 SIMPL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-134)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 147 a.a.        Molecular weight: 16368.84 Da        Isoelectric Point: 6.6853

>T148541 WP_130128276.1 NZ_CP047932:c320019-319579 [Synechococcus sp. WH 8101]
VILIDTNLWLYASLRETPHHSAAKAWLEATLNGDEAIALPWSVVLAVLCISTQHRLMLHPLKPEQALDLVEGWLQHPLVE
VLQPSRTHWDRLRLLLQDAGTAGNRTSDAHLAALAIEHNCLLCSADSDFRRFAGLRFCNPLRAAER

Download         Length: 441 bp

>T148541 NZ_CP063773:c4409160-4408840 [Pectobacterium carotovorum subsp. carotovorum PCCS1]
ATGCAAACATCACCTGCAATCCCTCCACGGGAGGATAACCTCTGTCCGTCACCTATAACCGTCCGGCAACAACTACTGAC
CTACCTGCTGGAAAAGCACTACGGCCTGACGCTGAATGACACACCATTCTGTGAGGAAAACGTGATTCAGGAGCATATCG
ATGCTGGCATCACGCTGGTCAATGCCGTCAATTTTCTGGTGGAGAAATACGAACTGGTGCGTATCGATCGCAACGGCTTT
AACTGGCAGGAGCAATCGCCGTTTCTTACCGCCGTTGATGTTCTCCGTGCCAGGCGTGCTACTGGTTTGCTCAAGGCATA
A

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9684.12 Da        Isoelectric Point: 10.3533

>AT148541 WP_130128277.1 NZ_CP047932:c320282-320016 [Synechococcus sp. WH 8101]
MRTTLSIDDVLLRQLRQKALDSGKPFKQVVNDTLRAGLHQAASPQRQPYRCPTFSIGALAPGVDLSKANQLAAGLEDEAL
LEKLRQSR

Download         Length: 267 bp

>AT148541 NZ_CP063773:c4409564-4409229 [Pectobacterium carotovorum subsp. carotovorum PCCS1]
ATGCCATCATCGGATACCCCGGAATGGGGACTAAAATGTGCCATCACTCCGCGATTCGGAGCCAGACTGGTGCAGGAAGG
CAACCGTCTGCACTATCTGGCAGACCGGGCCAGCGTTGTCGGTACGTTCAGTAAAACAGAAGCCCGTCATCTGGAACACG
TCTTCCCTGAGCTGATTAAGCAGTTGGAGCAGAAACTACGAACGGGAAAACTGAACCCCTGTCAGCAAGGCTGCATCGTG
CTGCATTGCAACGAATGGACCTGTGAAGCCGATACGCTGGGCAGTGTTGGCTACGTGTATATTGCTATTTATCCCTCTTC
AGCGGCAACACAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References