148540

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PhoH-LOG/-
Location 957615..959924 Replicon chromosome
Accession NZ_CP047931
Organism Synechococcus sp. A15-28

Toxin (Protein)


Gene name PhoH Uniprot ID -
Locus tag SynA1528_RS05195 Protein ID WP_186588003.1
Coordinates 957615..959003 (+) Length 463 a.a.

Antitoxin (Protein)


Gene name LOG Uniprot ID -
Locus tag SynA1528_RS05200 Protein ID WP_186588004.1
Coordinates 959028..959924 (+) Length 299 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SynA1528_RS05165 952984..953367 - 384 WP_186588001.1 hypothetical protein -
SynA1528_RS05170 953563..953865 + 303 WP_186588292.1 DUF1330 domain-containing protein -
SynA1528_RS05175 953859..954071 - 213 WP_186588002.1 hypothetical protein -
SynA1528_RS05180 954108..954320 - 213 WP_186586303.1 hypothetical protein -
SynA1528_RS05185 955149..955451 - 303 WP_186498750.1 hypothetical protein -
SynA1528_RS05190 956084..956266 - 183 WP_186483279.1 hypothetical protein -
SynA1528_RS05195 957615..959003 + 1389 WP_186588003.1 PhoH family protein Toxin
SynA1528_RS05200 959028..959924 + 897 WP_186588004.1 LOG family protein Antitoxin
SynA1528_RS05205 960331..960573 + 243 WP_186586302.1 hypothetical protein -
SynA1528_RS05210 960616..960903 - 288 WP_186588005.1 hypothetical protein -
SynA1528_RS05215 960869..961249 - 381 WP_186588293.1 hypothetical protein -
SynA1528_RS05220 961384..961554 + 171 WP_186498747.1 conjugal transfer protein TrbI -
SynA1528_RS05225 961991..962338 - 348 WP_186588006.1 hypothetical protein -
SynA1528_RS05230 962367..962564 - 198 WP_186588294.1 hypothetical protein -
SynA1528_RS05235 962648..963202 + 555 WP_186588007.1 hypothetical protein -
SynA1528_RS05240 963795..964112 + 318 WP_186588295.1 DUF3303 domain-containing protein -
SynA1528_RS05245 964325..964555 - 231 WP_186588008.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 952758..964555 11797


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PhoH-like protein

(239-454)

Antitoxin

LOG family

(158-288)


Sequences

Toxin        


Download         Length: 463 a.a.        Molecular weight: 50669.51 Da        Isoelectric Point: 5.4471

>T148540 WP_186588003.1 NZ_CP047931:957615-959003 [Synechococcus sp. A15-28]
MKNKIVVLDTNVLLHDPEAPHRFGDLRVVIPMQVVEEIDRFKKDHSEKGRNARRISRLLDSFRDRGCLADGVPIEGTNHG
LLQVIFCQAHALDALPAELQGGGGDNNILAVALEQLRCGGLKQAPEVVLISKDINLRIKADAVGLQAEDYVNDNVSIDDL
YAGFRELSTDAVTISSLHDEGQLPLDAVTDPEGQHPQANEGVVLVDERNDSHTLLARRQGNSNSLEPLHWLNRAHLGRIK
ARNREQSFALDLLLDPSVALVTLVGKAGTGKTLLAIAAGLHQVADTHHYARLLVTRPPISLGKDIGYLPGTLEEKLGPWM
KPIIDNIDFITGSSPGEESEQTKKQRHREPRNAWADLQGMGLLEVEAINTIRGRSIPQQFLVVDEAQNLTPLEVKTIVTR
VGDGTKVVFTGDPHQIDNPYVDAESNGLTWLVEKLKDQPLVGHITLTKGERSELAELAANIL

Download         Length: 1389 bp

>T148540 NZ_CP063773:c4407565-4407161 [Pectobacterium carotovorum subsp. carotovorum PCCS1]
ATGCTGAAATATCTACTTGATACCAATATCTGTATTTACACTATCAAGAACAAACCGCAAGAAGTCAGAGACGCTTTCTA
CCTCCATTACGGGCAGTTTGCTATCAGTTCTATCACGCTGATGGAACTGATCTATGGTGCGGAGAAATCGATAAATCCAG
AAAAGAATCTCGCCGTAATTGAAGGGTTTTCTGCACGTATGGAAGTGCAAACTTATGGTTTTGACGCCGCCGTACATACG
GGGCAAATTCGTGCGGAACTGGCAAGACAAGGAGCACCCATCGGCCCGTATGATGCCATGTTAGCGGGGCAAGCACGGTC
CGCAGGCTTGATTCTGGTAACGAACAATGTGCGTGAGTTTGAGCGTGTGCCAGGATTGCGCGTAGAAAACTGGGTTGGTA
GATAG

Antitoxin


Download         Length: 299 a.a.        Molecular weight: 33181.64 Da        Isoelectric Point: 5.5579

>AT148540 WP_186588004.1 NZ_CP047931:959028-959924 [Synechococcus sp. A15-28]
MTVEHMTQFPETSTPEQANLDAILNSPTYRIAHEDPELMNSNVMRGVRMLLEITKPDLHLETAGIESTIIVFGGARIVDR
DTAHQQLKDAEKNLNQDPNSSTLKRKVINAQHLIELSRFYDAARQFAYLASQHGQASKGQGHGCASHVIVTGGGPGIMEA
ANRGAFEAGCRSIGLNIALPFEQHPNAYITQDLCFKFNYFSLRKFHFVMRSVGAILFPGGFGTLDELFELLTLRQVGTKG
RMPIVLFGTEFWTKLVDFDYLAELGLISNDDLALIRFSDTAEEAWEYIQSSTEPVRGQ

Download         Length: 897 bp

>AT148540 NZ_CP063773:c4407795-4407565 [Pectobacterium carotovorum subsp. carotovorum PCCS1]
ATGGAAAAAACTACAGTATTTAAAAGCAATCGCAGTCAGGCGGTACGACTCCCTAAAGCCGTTGCACTGCCGGATGATGT
GAAGCAGGTTGATATCGTTGCGATTGGCCGTACACGTATTATCACGCCAGCAGGCGAAAGCTGGGATAGTTGGTTTGAAG
GGGAGAGCGTAACACCTGACTTCATGATCACCAGGGAGCAGCCCGATGATCAGATCAGGGAAGATTTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References