Detailed information of TA system TA148495

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-Phd
• Location: 2920839..2921404
• Replicon: chromosome
• Accession: NZ_CP047898
• Organism: Pseudarthrobacter sp. YJ56

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: GU243_RS13710
• Protein ID: WP_201762504.1
• Coordinates: 2920839..2921093 (-)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: GU243_RS13715
• Protein ID: WP_160675034.1
• Coordinates: 2921129..2921404 (-)
• Length: 92 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
GU243_RS13695	2916490..2917821	-	1332	WP_160675022.1	extracellular solute-binding protein	-
GU243_RS13700	2918005..2919003	-	999	WP_160675025.1	LacI family transcriptional regulator	-
GU243_RS13705	2919182..2920438	+	1257	WP_160675028.1	FAD-binding protein	-
GU243_RS13710	2920839..2921093	-	255	WP_201762504.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
GU243_RS13715	2921129..2921404	-	276	WP_160675034.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
GU243_RS13720	2921673..2922701	-	1029	Protein_2720	LacI family DNA-binding transcriptional regulator	-
GU243_RS13725	2922997..2924316	+	1320	WP_160675037.1	extracellular solute-binding protein	-
GU243_RS13730	2924319..2925221	+	903	WP_201762276.1	sugar ABC transporter permease	-
GU243_RS13735	2925221..2926120	+	900	WP_160675040.1	carbohydrate ABC transporter permease	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (1-81)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-71)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 9612.07 Da
• Isoelectric Point: 10.3378

>T148495 WP_201762504.1 NZ_CP047898:c2921093-2920839 [Pseudarthrobacter sp. YJ56]
IEVTSPALKGFRRLPEKAAAAIVEFVTGVLADNPRRLSKPLTNELLGLRTARRGDYRVLFTLDIEEHTSYVHRIEHRADV
YKPR

Nucleotide

• Length: 255 bp

>T148495 NZ_CP063748:307078-307362 [Klebsiella pneumoniae]
ATGACCTATAAGCTGGCCTTTAATGAATCAGCTCTGAAAGAATGGAAAAAATTGGGCCATACCATTAGGGAACAATTCAA
AAAGAAGCTCGCTGAGCGCCTGTTGAACCCACGGGTGCCCGCATCGCAACTCCATGGACGCAAAGACCAGTACAAAATAA
AGCTCCGTGGCGCAGGCTACCGACTGGTTTACAGTGTCAACGATGATGTTGTGACGGTCACCGTAATTGGCGTCGGTAAA
CGTGAGAATGATGATATTTACAATTTGACCAAACACAGAAATTAA

Antitoxin

Protein

• Length: 92 a.a.
• Molecular weight: 10164.33 Da
• Isoelectric Point: 4.7052

>AT148495 WP_160675034.1 NZ_CP047898:c2921404-2921129 [Pseudarthrobacter sp. YJ56]
MRTVPLSEAKDKLSALVEEADKTHEIIQITRHGHPSAVLMSADDLESLQETIHWLSQPGIREDLDQARRDIAEGNTVSGD
DLRHEFGLPPK

Nucleotide

• Length: 276 bp

>AT148495 NZ_CP063748:306840-307088 [Klebsiella pneumoniae]
ATGGCATTTCAGGTACTAACCACTACTGCAGCAAGCATCACAGAGCTTAAACGTGATCCTATGGGTACTTTCAATGCAGG
AGAAGGTGCCCCGGTAGCCATACTCAATCGCAACGAACCCGCTTTTTACTGTGTACCGCCTGCTCTGTATGCTCAACTGA
TGGAGCTTCTTGAAGATCAGGAGTTGGGTCGTATTGCTGATGAGCGAATTGGTGAGGCTGTAATCGAGGTCAGTCTAGAT
GACCTATAA