Detailed information of TA system
Overview
TA module
Type | II | Classification (family/domain) | TsdAT/- |
Location | 2741602..2742116 | Replicon | chromosome |
Accession | NZ_CP047794 | ||
Organism | Staphylococcus aureus strain UP_551 |
Toxin (Protein)
Gene name | TsdT | Uniprot ID | T1YA99 |
Locus tag | E3S81_RS13470 | Protein ID | WP_000581792.1 |
Coordinates | 2741907..2742116 (+) | Length | 70 a.a. |
Antitoxin (Protein)
Gene name | TsdA | Uniprot ID | W8UW13 |
Locus tag | E3S81_RS13465 | Protein ID | WP_000138932.1 |
Coordinates | 2741602..2741895 (+) | Length | 98 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
E3S81_RS13440 | 2737047..2737688 | + | 642 | WP_000483160.1 | thiamine phosphate synthase | - |
E3S81_RS13445 | 2737774..2738646 | + | 873 | WP_000725802.1 | membrane protein insertase YidC | - |
E3S81_RS13455 | 2739277..2739924 | - | 648 | WP_001187620.1 | HD domain-containing protein | - |
E3S81_RS13460 | 2739952..2741436 | - | 1485 | WP_000571551.1 | cardiolipin synthase | - |
E3S81_RS13465 | 2741602..2741895 | + | 294 | WP_000138932.1 | copper-sensing transcriptional repressor CsoR | Antitoxin |
E3S81_RS13470 | 2741907..2742116 | + | 210 | WP_000581792.1 | heavy-metal-associated domain-containing protein | Toxin |
E3S81_RS13475 | 2742244..2742381 | + | 138 | WP_000828354.1 | hypothetical protein | - |
E3S81_RS13480 | 2742645..2743847 | - | 1203 | WP_070867581.1 | rod shape-determining protein RodA | - |
E3S81_RS13485 | 2744165..2745235 | + | 1071 | WP_000159631.1 | D-alanine--D-alanine ligase | - |
E3S81_RS13490 | 2745250..2746608 | + | 1359 | WP_047213666.1 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 70 a.a. Molecular weight: 7843.77 Da Isoelectric Point: 4.1008
>T147821 WP_000581792.1 NZ_CP047794:2741907-2742116 [Staphylococcus aureus]
MIHQNTIYTAGIETEEQVSQLTERISNMIGVHQVNINIIDGQVTVSYETPANLNSIEKEIYDEGYKIVF
MIHQNTIYTAGIETEEQVSQLTERISNMIGVHQVNINIIDGQVTVSYETPANLNSIEKEIYDEGYKIVF
Download Length: 210 bp
>T147821 NZ_CP063332:c203113-203006 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA
Antitoxin
Download Length: 98 a.a. Molecular weight: 11197.82 Da Isoelectric Point: 6.2243
>AT147821 WP_000138932.1 NZ_CP047794:2741602-2741895 [Staphylococcus aureus]
MTEQDNAHHSEQIKTNLKSRLNRIEGQVRAINRMIEEDVYCDDVLTQIRATRSALNSVAIKLLEQHMKSCIMNKVNQGAQ
EEAMEELLVTFQKLIKD
MTEQDNAHHSEQIKTNLKSRLNRIEGQVRAINRMIEEDVYCDDVLTQIRATRSALNSVAIKLLEQHMKSCIMNKVNQGAQ
EEAMEELLVTFQKLIKD
Download Length: 294 bp
>AT147821 NZ_CP063332:203161-203227 [Escherichia coli]
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTGTACCTCTCAACGTGCGGGGGTTTTCTC
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTGTACCTCTCAACGTGCGGGGGTTTTCTC
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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