Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1813831..1813976 Replicon chromosome
Accession NZ_CP047707
Organism Klebsiella pneumoniae strain Kpn-13

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1813867..1813969 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1813831..1813976 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GVI78_RS08800 1808961..1811021 + 2061 WP_004151449.1 oligopeptidase B -
GVI78_RS08805 1811025..1811684 - 660 WP_002911407.1 exodeoxyribonuclease X -
GVI78_RS08810 1811763..1811993 - 231 WP_002911406.1 DNA polymerase III subunit theta -
GVI78_RS08815 1812106..1812480 + 375 WP_004151448.1 CopC domain-containing protein YobA -
GVI78_RS08820 1812484..1813353 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
GVI78_RS08825 1813370..1813708 + 339 WP_016529031.1 YebY family protein -
- 1813831..1813976 - 146 - - Antitoxin
- 1813867..1813969 + 103 - - Toxin
GVI78_RS08830 1814345..1814488 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
GVI78_RS08835 1814593..1815561 - 969 WP_004151446.1 VirK/YbjX family protein -
GVI78_RS08840 1815718..1816371 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
GVI78_RS08845 1816368..1816559 - 192 WP_002911395.1 YebW family protein -
GVI78_RS08850 1816657..1816896 - 240 WP_002911393.1 YebV family protein -
GVI78_RS08855 1817012..1818445 - 1434 WP_048292090.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T147368 NZ_CP047707:1813867-1813969 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT147368 NZ_CP047707:c1813976-1813831 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References