Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1902436..1902581 Replicon chromosome
Accession NZ_CP047700
Organism Klebsiella pneumoniae strain Kpn-14

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1902472..1902574 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1902436..1902581 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GVI79_RS09405 1897566..1899626 + 2061 WP_004151449.1 oligopeptidase B -
GVI79_RS09410 1899630..1900289 - 660 WP_002911407.1 exodeoxyribonuclease X -
GVI79_RS09415 1900368..1900598 - 231 WP_002911406.1 DNA polymerase III subunit theta -
GVI79_RS09420 1900711..1901085 + 375 WP_004151448.1 CopC domain-containing protein YobA -
GVI79_RS09425 1901089..1901958 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
GVI79_RS09430 1901975..1902313 + 339 WP_002911404.1 YebY family protein -
- 1902436..1902581 - 146 - - Antitoxin
- 1902472..1902574 + 103 - - Toxin
GVI79_RS09435 1902948..1903091 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
GVI79_RS09440 1903196..1904164 - 969 WP_004151446.1 VirK/YbjX family protein -
GVI79_RS09445 1904321..1904974 + 654 WP_197348489.1 protein-serine/threonine phosphatase -
GVI79_RS09450 1904971..1905162 - 192 WP_002911395.1 YebW family protein -
GVI79_RS09455 1905260..1905499 - 240 WP_002911393.1 YebV family protein -
GVI79_RS09460 1905615..1907048 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T147349 NZ_CP047700:1902472-1902574 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT147349 NZ_CP047700:c1902581-1902436 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References